product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
Munc 13-1
catalog :
126 111
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
266B1
reactivity :
mouse, rat, zebrafish
application :
western blot, ELISA, immunoprecipitation
more info or order :
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; loading ...; fig s6a
Wang Y, Figueiredo D, Sun X, Dong Z, Chen W, Cui W, et al. Controlling of glutamate release by neuregulin3 via inhibiting the assembly of the SNARE complex. Proc Natl Acad Sci U S A. 2018;115:2508-2513 pubmed publisher
Emperador Melero J, Huson V, Van Weering J, Bollmann C, Fischer von Mollard G, Toonen R, et al. Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi. Nat Commun. 2018;9:3421 pubmed publisher
de Jong A, Roggero C, Ho M, Wong M, Brautigam C, Rizo J, et al. RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes. Neuron. 2018;98:335-349.e7 pubmed publisher
Ram rez Franco J, Alonso B, Bartolom Mart n D, S nchez Prieto J, Torres M. Studying synaptic efficiency by post-hoc immunolabelling. BMC Neurosci. 2013;14:127 pubmed publisher
Kaeser Woo Y, Younts T, Yang X, Zhou P, Wu D, Castillo P, et al. Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP. J Neurosci. 2013;33:9769-80 pubmed publisher
Dudenhöffer Pfeifer M, Schirra C, Pattu V, Halimani M, Maier Peuschel M, Marshall M, et al. Different Munc13 isoforms function as priming factors in lytic granule release from murine cytotoxic T lymphocytes. Traffic. 2013;14:798-809 pubmed publisher
Maas C, Torres V, Altrock W, Leal Ortiz S, Wagh D, Terry Lorenzo R, et al. Formation of Golgi-derived active zone precursor vesicles. J Neurosci. 2012;32:11095-108 pubmed publisher
Oh E, Kalwat M, Kim M, Verhage M, Thurmond D. Munc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoforms. J Biol Chem. 2012;287:25821-33 pubmed publisher
Bartolomé Martín D, Ramírez Franco J, Castro E, Sánchez Prieto J, Torres M. Efficient synaptic vesicle recycling after intense exocytosis concomitant with the accumulation of non-releasable endosomes at early developmental stages. J Cell Sci. 2012;125:422-34 pubmed publisher
Martín R, Bartolomé Martín D, Torres M, Sánchez Prieto J. Non-additive potentiation of glutamate release by phorbol esters and metabotropic mGlu7 receptor in cerebrocortical nerve terminals. J Neurochem. 2011;116:476-85 pubmed publisher
Ren Q, Wimmer C, Chicka M, Ye S, Ren Y, Hughson F, et al. Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis. Blood. 2010;116:869-77 pubmed publisher
Martín R, Durroux T, Ciruela F, Torres M, Pin J, Sánchez Prieto J. The metabotropic glutamate receptor mGlu7 activates phospholipase C, translocates munc-13-1 protein, and potentiates glutamate release at cerebrocortical nerve terminals. J Biol Chem. 2010;285:17907-17 pubmed publisher
Groffen A, Martens S, Díez Arazola R, Cornelisse L, Lozovaya N, de Jong A, et al. Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release. Science. 2010;327:1614-8 pubmed publisher
Takamori S, Holt M, Stenius K, Lemke E, Gr Nborg M, Riedel D, et al. Molecular anatomy of a trafficking organelle. Cell. 2006;127:831-46 pubmed publisher
Deguchi Tawarada M, Inoue E, Takao Rikitsu E, Inoue M, Kitajima I, Ohtsuka T, et al. Active zone protein CAST is a component of conventional and ribbon synapses in mouse retina. J Comp Neurol. 2006;495:480-96 pubmed
product information
Cat. Nr. :
126 111
Antigen :
Munc 13-1
Synonyms :
Munc 13-1, Munc 13-2, Munc 13-3
Host Species :
mouse
Tpye :
monoclonal
Form :
purified IgG
Cell Line :
266B1
Subtype :
IgG2b
Immunogen :
Recombinant protein corresponding to AA 3 to 317 from rat Munc13-1 (UniProt Id: Q62768)
Reactivity :
rat, mouse, zebrafish
WB :
y
IP :
y
ICC :
lim
IHC :
?
IHC P :
?
ELISA :
y
KO :
1
Quantity :
100 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany