product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
PSD95
catalog :
124 011
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1,08E+12
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section
more info or order :
citations: 33
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:5000; loading ...; fig 4d
Zhang R, Liakath Ali K, Sudhof T. Latrophilin-2 and latrophilin-3 are redundantly essential for parallel-fiber synapse function in cerebellum. elife. 2020;9: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 3s1a
Kaczmarek Hájek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, et al. Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. elife. 2018;7: pubmed publisher
  • western blot; mouse; loading ...; fig 4c
Barad Z, Grattan D, Leitch B. NMDA Receptor Expression in the Thalamus of the Stargazer Model of Absence Epilepsy. Sci Rep. 2017;7:42926 pubmed publisher
  • immunohistochemistry; mouse; 1 mg/l; loading ...; fig 3b
Sohn J, Okamoto S, Kataoka N, Kaneko T, Nakamura K, Hioki H. Differential Inputs to the Perisomatic and Distal-Dendritic Compartments of VIP-Positive Neurons in Layer 2/3 of the Mouse Barrel Cortex. Front Neuroanat. 2016;10:124 pubmed publisher
  • western blot; mouse; 1:1000
Sun X, Li L, Liu F, Huang Z, Bean J, Jiao H, et al. Lrp4 in astrocytes modulates glutamatergic transmission. Nat Neurosci. 2016;19:1010-8 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 1b
Hensel N, Schön A, Konen T, Lübben V, Förthmann B, Baron O, et al. Fibroblast growth factor 23 signaling in hippocampal cells: impact on neuronal morphology and synaptic density. J Neurochem. 2016;137:756-69 pubmed publisher
  • western blot; rat; 1:1000; fig 1
Schoen M, Reichel J, Demestre M, Putz S, Deshpande D, Proepper C, et al. Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons. Front Cell Neurosci. 2015;9:496 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6a
Valenza M, Chen J, Di Paolo E, Ruozi B, Belletti D, Ferrari Bardile C, et al. Cholesterol-loaded nanoparticles ameliorate synaptic and cognitive function in Huntington's disease mice. EMBO Mol Med. 2015;7:1547-64 pubmed publisher
Inagaki R, Moriguchi S, Fukunaga K. Kir6.1 Heterozygous Mice Exhibit Aberrant Amygdala-Dependent Cued Fear Memory. Mol Neurobiol. 2019;: pubmed publisher
Klotz L, Wendler O, Frischknecht R, Shigemoto R, Schulze H, Enz R. Localization of group II and III metabotropic glutamate receptors at pre- and postsynaptic sites of inner hair cell ribbon synapses. FASEB J. 2019;33:13734-13746 pubmed publisher
Lazarevic V, Mantas I, Flais I, Svenningsson P. Fluoxetine Suppresses Glutamate- and GABA-Mediated Neurotransmission by Altering SNARE Complex. Int J Mol Sci. 2019;20: pubmed publisher
Sun X, Chen W, Sun D, Huang J, Li Y, Pan J, et al. Neogenin in Amygdala for Neuronal Activity and Information Processing. J Neurosci. 2018;38:9600-9613 pubmed publisher
Lazarevic V, Yang Y, Ivanova D, Fejtova A, Svenningsson P. Riluzole attenuates the efficacy of glutamatergic transmission by interfering with the size of the readily releasable neurotransmitter pool. Neuropharmacology. 2018;143:38-48 pubmed publisher
Emperador Melero J, Huson V, Van Weering J, Bollmann C, Fischer von Mollard G, Toonen R, et al. Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi. Nat Commun. 2018;9:3421 pubmed publisher
Borin M, Saraceno C, Catania M, Lorenzetto E, Pontelli V, Paterlini A, et al. Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer's disease. Acta Neuropathol Commun. 2018;6:61 pubmed publisher
Li J, Shalev Benami M, Sando R, Jiang X, Kibrom A, Wang J, et al. Structural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse. Cell. 2018;173:735-748.e15 pubmed publisher
Cavalcanti de Albuquerque J, de Souza Ferreira E, de Carvalho D, Galina A. Mitochondria-Bound Hexokinase (mt-HK) Activity Differ in Cortical and Hypothalamic Synaptosomes: Differential Role of mt-HK in H2O2 Depuration. Mol Neurobiol. 2018;55:5889-5900 pubmed publisher
Anderson G, Maxeiner S, Sando R, Tsetsenis T, Malenka R, Südhof T. Postsynaptic adhesion GPCR latrophilin-2 mediates target recognition in entorhinal-hippocampal synapse assembly. J Cell Biol. 2017;216:3831-3846 pubmed publisher
McDonough P, Prigozhina N, Basa R, Price J. Assay of Calcium Transients and Synapses in Rat Hippocampal Neurons by Kinetic Image Cytometry and High-Content Analysis: An In Vitro Model System for Postchemotherapy Cognitive Impairment. Assay Drug Dev Technol. 2017;15:220-236 pubmed publisher
Reim D, Distler U, Halbedl S, Verpelli C, Sala C, Bockmann J, et al. Proteomic Analysis of Post-synaptic Density Fractions from Shank3 Mutant Mice Reveals Brain Region Specific Changes Relevant to Autism Spectrum Disorder. Front Mol Neurosci. 2017;10:26 pubmed publisher
Chiacchiaretta M, Latifi S, Bramini M, Fadda M, Fassio A, Benfenati F, et al. Neuronal hyperactivity causes Na+/H+ exchanger-induced extracellular acidification at active synapses. J Cell Sci. 2017;130:1435-1449 pubmed publisher
Soykan T, Kaempf N, Sakaba T, Vollweiter D, Goerdeler F, Puchkov D, et al. Synaptic Vesicle Endocytosis Occurs on Multiple Timescales and Is Mediated by Formin-Dependent Actin Assembly. Neuron. 2017;93:854-866.e4 pubmed publisher
Sialana F, Gulyassy P, Májek P, Sjöstedt E, Kis V, Müller A, et al. Mass spectrometric analysis of synaptosomal membrane preparations for the determination of brain receptors, transporters and channels. Proteomics. 2016;16:2911-2920 pubmed publisher
Hakim V, Cohen L, Zuchman R, Ziv T, Ziv N. The effects of proteasomal inhibition on synaptic proteostasis. EMBO J. 2016;35:2238-2262 pubmed
Valente P, Castroflorio E, Rossi P, Fadda M, Sterlini B, Cervigni R, et al. PRRT2 Is a Key Component of the Ca(2+)-Dependent Neurotransmitter Release Machinery. Cell Rep. 2016;15:117-131 pubmed publisher
Nigam S, Xu S, Ackermann F, Gregory J, Lundkvist J, Lendahl U, et al. Endogenous APP accumulates in synapses after BACE1 inhibition. Neurosci Res. 2016;109:9-15 pubmed publisher
Kumar A, Mallick B. Long-term primary culture of neurons taken from chick embryo brain: A model to study neural cell biology, synaptogenesis and its dynamic properties. J Neurosci Methods. 2016;263:123-33 pubmed publisher
Fossati G, Morini R, Corradini I, Antonucci F, Trepte P, Edry E, et al. Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis. Cell Death Differ. 2015;22:1425-36 pubmed publisher
Manca P, Mameli O, Caria M, Torrej n Escribano B, Blasi J. Distribution of SNAP25, VAMP1 and VAMP2 in mature and developing deep cerebellar nuclei after estrogen administration. Neuroscience. 2014;266:102-15 pubmed publisher
Murase S, McKay R. Neuronal activity-dependent STAT3 localization to nucleus is dependent on Tyr-705 and Ser-727 phosphorylation in rat hippocampal neurons. Eur J Neurosci. 2014;39:557-65 pubmed publisher
Cohen L, Zuchman R, Sorokina O, Müller A, Dieterich D, Armstrong J, et al. Metabolic turnover of synaptic proteins: kinetics, interdependencies and implications for synaptic maintenance. PLoS ONE. 2013;8:e63191 pubmed publisher
Schmeisser M, Baumann B, Johannsen S, Vindedal G, Jensen V, Hvalby Ø, et al. I?B kinase/nuclear factor ?B-dependent insulin-like growth factor 2 (Igf2) expression regulates synapse formation and spine maturation via Igf2 receptor signaling. J Neurosci. 2012;32:5688-703 pubmed publisher
Perlini L, Botti F, Fornasiero E, Giannandrea M, Bonanomi D, Amendola M, et al. Effects of phosphorylation and neuronal activity on the control of synapse formation by synapsin I. J Cell Sci. 2011;124:3643-53 pubmed publisher
product information
Cat. Nr. :
124 011
Antigen :
PSD95
Synonyms :
SAP 90, DLG 4, Disks large homolog 4, DLGH 4, PSD 95, SAP90, SAP 90
Host Species :
mouse
Tpye :
monoclonal
Form :
purified IgG
Cell Line :
1,08E+12
Subtype :
IgG1
Immunogen :
Recombinant protein corresponding to AA 64 to 247 from mouse PSD95 (UniProt Id: Q62108)
Reactivity :
rat, mouse, chicken
WB :
WB
IP :
IP
ICC :
ICC
KO :
yes
Quantity :
100 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany