product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
Rab 3
catalog :
107 011
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
42.1
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; rat; loading ...; fig 4i
Wang R, Cao X, Kulej K, Liu W, Ma T, MacDonald M, et al. Uncovering BRD4 hyperphosphorylation associated with cellular transformation in NUT midline carcinoma. Proc Natl Acad Sci U S A. 2017;114:E5352-E5361 pubmed publisher
  • western blot; mouse; loading ...; tbl 1
Cao M, Wu Y, Ashrafi G, McCartney A, Wheeler H, Bushong E, et al. Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons. Neuron. 2017;93:882-896.e5 pubmed publisher
Kindt K, SHEETS L. Transmission Disrupted: Modeling Auditory Synaptopathy in Zebrafish. Front Cell Dev Biol. 2018;6:114 pubmed publisher
Caswell P, Dickens M. JIP3 localises to exocytic vesicles and focal adhesions in the growth cones of differentiated PC12 cells. Mol Cell Biochem. 2018;444:1-13 pubmed publisher
Cazares V, Njus M, Manly A, Saldate J, Subramani A, Ben Simon Y, et al. Dynamic Partitioning of Synaptic Vesicle Pools by the SNARE-Binding Protein Tomosyn. J Neurosci. 2016;36:11208-11222 pubmed
Liu Y, Li H, Sugiura Y, Han W, Gallardo G, Khvotchev M, et al. Ubiquitin-Synaptobrevin Fusion Protein Causes Degeneration of Presynaptic Motor Terminals in Mice. J Neurosci. 2015;35:11514-31 pubmed publisher
Armstrong A, Mattsson N, Appelqvist H, Janefjord C, Sandin L, Agholme L, et al. Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease. Neuromolecular Med. 2014;16:150-60 pubmed publisher
Kaeser Woo Y, Younts T, Yang X, Zhou P, Wu D, Castillo P, et al. Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP. J Neurosci. 2013;33:9769-80 pubmed publisher
Fern ndez Busnadiego R, Asano S, Oprişoreanu A, Sakata E, Doengi M, Kochovski Z, et al. Cryo-electron tomography reveals a critical role of RIM1? in synaptic vesicle tethering. J Cell Biol. 2013;201:725-40 pubmed publisher
Zheng L, Cedazo Minguez A, Hallbeck M, Jerhammar F, Marcusson J, Terman A. Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system. Transl Neurodegener. 2012;1:19 pubmed publisher
Einhorn Z, Trapani J, Liu Q, Nicolson T. Rabconnectin3? promotes stable activity of the H+ pump on synaptic vesicles in hair cells. J Neurosci. 2012;32:11144-56 pubmed publisher
Wang X, Wang Q, Yang S, Bucan M, Rich M, Engisch K. Impaired activity-dependent plasticity of quantal amplitude at the neuromuscular junction of Rab3A deletion and Rab3A earlybird mutant mice. J Neurosci. 2011;31:3580-8 pubmed publisher
Schonn J, van Weering J, Mohrmann R, Schlüter O, Sudhof T, de Wit H, et al. Rab3 proteins involved in vesicle biogenesis and priming in embryonic mouse chromaffin cells. Traffic. 2010;11:1415-28 pubmed publisher
Groffen A, Martens S, Díez Arazola R, Cornelisse L, Lozovaya N, de Jong A, et al. Doc2b is a high-affinity Ca2+ sensor for spontaneous neurotransmitter release. Science. 2010;327:1614-8 pubmed publisher
Herzog E, Takamori S, Jahn R, Brose N, Wojcik S. Synaptic and vesicular co-localization of the glutamate transporters VGLUT1 and VGLUT2 in the mouse hippocampus. J Neurochem. 2006;99:1011-8 pubmed
Barile M, Pisitkun T, Yu M, Chou C, Verbalis M, Shen R, et al. Large scale protein identification in intracellular aquaporin-2 vesicles from renal inner medullary collecting duct. Mol Cell Proteomics. 2005;4:1095-106 pubmed
Smith A, Pfeiffer J, Zhang J, Martinez A, Griffiths G, Wilson B. Microtubule-dependent transport of secretory vesicles in RBL-2H3 cells. Traffic. 2003;4:302-12 pubmed
Lang T, Margittai M, Hölzler H, Jahn R. SNAREs in native plasma membranes are active and readily form core complexes with endogenous and exogenous SNAREs. J Cell Biol. 2002;158:751-60 pubmed
Morante Redolat J, Gorostidi Pagola A, Piquer Sirerol S, Saenz A, Poza J, Galán J, et al. Mutations in the LGI1/Epitempin gene on 10q24 cause autosomal dominant lateral temporal epilepsy. Hum Mol Genet. 2002;11:1119-28 pubmed
product information
Company Name :
Synaptic Systems
Cat. Nr. :
107 011
Antigen :
Rab 3
Synonyms :
Rab 3a, Rab 3c, Rab 3d, rab3
Host Species :
mouse
Tpye :
monoclonal
Form :
purified IgG
Cell Line :
42.1
Subtype :
IgG1
Immunogen :
Recombinant protein corresponding to AA 1 to 220 from rat Rab3a (UniProt Id: P63012)
Reactivity :
human, rat, mouse, vertebrates
WB :
y
IP :
no
ICC :
y
IHC :
y
IHC P :
y
EM :
y
Quantity :
100 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany