product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
Synapsin 1
catalog :
106 103
quantity :
50 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
/
reactivity :
human, mouse, rat, zebrafish
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 1b
Sun A, Yuan Q, Fukuda M, Yu W, Yan H, Lim G, et al. Potassium channel dysfunction in human neuronal models of Angelman syndrome. Science. 2019;366:1486-1492 pubmed publisher
  • western blot; mouse; 1:4000; fig 3i
Lüningschrör P, Binotti B, Dombert B, Heimann P, Pérez Lara A, Slotta C, et al. Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nat Commun. 2017;8:678 pubmed publisher
  • immunocytochemistry; rat; loading ...; fig 6b
Efimova N, Korobova F, Stankewich M, Moberly A, Stolz D, Wang J, et al. ?III Spectrin Is Necessary for Formation of the Constricted Neck of Dendritic Spines and Regulation of Synaptic Activity in Neurons. J Neurosci. 2017;37:6442-6459 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 3a
  • western blot; mouse; 1:2000; loading ...; fig 1a
Horvath P, Kavalali E, Monteggia L. CRISPR/Cas9 system-mediated impairment of synaptobrevin/VAMP function in postmitotic hippocampal neurons. J Neurosci Methods. 2017;278:57-64 pubmed publisher
  • immunocytochemistry; human; fig 5
Rooney G, Goodwin A, Depeille P, Sharir A, Schofield C, Yeh E, et al. Human iPS Cell-Derived Neurons Uncover the Impact of Increased Ras Signaling in Costello Syndrome. J Neurosci. 2016;36:142-52 pubmed publisher
Gerth F, Jäpel M, Sticht J, Kuropka B, Schmitt X, Driller J, et al. Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain. Structure. 2019;27:977-987.e5 pubmed publisher
Wang J, Chen Y, Zhang C, Xiang Z, Ding J, Han X. Learning and memory deficits and alzheimer's disease-like changes in mice after chronic exposure to microcystin-LR. J Hazard Mater. 2019;373:504-518 pubmed publisher
Molday L, Cheng C, Molday R. Cell-Specific Markers for the Identification of Retinal Cells and Subcellular Organelles by Immunofluorescence Microscopy. Methods Mol Biol. 2019;1834:293-310 pubmed publisher
López Erauskin J, Tadokoro T, Baughn M, Myers B, McAlonis Downes M, Chillon Marinas C, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. 2018;100:816-830.e7 pubmed publisher
Lehrman E, Wilton D, Litvina E, Welsh C, Chang S, Frouin A, et al. CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development. Neuron. 2018;100:120-134.e6 pubmed publisher
Tsunemoto R, Lee S, Szucs A, Chubukov P, Sokolova I, Blanchard J, et al. Diverse reprogramming codes for neuronal identity. Nature. 2018;557:375-380 pubmed publisher
Luo F, Zhang J, Burke K, Romito Digiacomo R, Miller R, Yang Y. Oligodendrocyte-specific loss of Cdk5 disrupts the architecture of nodes of Ranvier as well as learning and memory. Exp Neurol. 2018;306:92-104 pubmed publisher
Lee J, Han S, Park M, Baek B, Song I, Choi M, et al. Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease. Nat Commun. 2018;9:1479 pubmed publisher
Park D, Chang S. Soluble Aβ1-42 increases the heterogeneity in synaptic vesicle pool size among synapses by suppressing intersynaptic vesicle sharing. Mol Brain. 2018;11:10 pubmed publisher
Krencik R, Seo K, van Asperen J, Basu N, Cvetkovic C, Barlas S, et al. Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes. Stem Cell Reports. 2017;9:1745-1753 pubmed publisher
McDonough P, Prigozhina N, Basa R, Price J. Assay of Calcium Transients and Synapses in Rat Hippocampal Neurons by Kinetic Image Cytometry and High-Content Analysis: An In Vitro Model System for Postchemotherapy Cognitive Impairment. Assay Drug Dev Technol. 2017;15:220-236 pubmed publisher
product information
Cat. Nr. :
106 103
Antigen :
Synapsin 1
Synonyms :
Syn1
Host Species :
rabbit
Tpye :
polyclonal
Form :
affinity purified
Immunogen :
Synthetic peptide corresponding to AA 445 to 462 from mouse Synapsin1 (UniProt Id: O88935)
Reactivity :
human, rat, mouse, pig, zebrafish
WB :
WB
IP :
IP
ICC :
ICC
IHC :
IHC
IHC P :
IHC-P
KO :
yes
Quantity :
50 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany