product summary
Loading...
company name :
Synaptic Systems
product type :
antibody
product name :
Synaptophysin 1
catalog :
101 011
quantity :
50 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
07. Feb
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 129
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 1d
Quadros A, Arazola R, xc1 lvarez A, Pires J, Meredith R, Saarloos I, et al. Neuronal F-Box protein FBXO41 regulates synaptic transmission and hippocampal network maturation. iScience. 2022;25:104069 pubmed publisher
  • western blot; mouse; loading ...; fig 4e
Pérez Sisqués L, Sancho Balsells A, Solana Balaguer J, Campoy Campos G, Vives Isern M, Soler Palazón F, et al. RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer's disease. Cell Death Dis. 2021;12:616 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 9a
Kim W, Watanabe H, Lomoio S, Tesco G. Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo. J Biol Chem. 2021;296:100372 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 3c
Steinkellner T, Madany M, Haberl M, Zell V, Li C, Hu J, et al. Genetic Probe for Visualizing Glutamatergic Synapses and Vesicles by 3D Electron Microscopy. ACS Chem Neurosci. 2021;12:626-639 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 5b
Sclip A, Sudhof T. LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses. elife. 2020;9: pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4a
Su J, Charalambakis N, Sabbagh U, Somaiya R, Monavarfeshani A, Guido W, et al. Retinal inputs signal astrocytes to recruit interneurons into visual thalamus. Proc Natl Acad Sci U S A. 2020;117:2671-2682 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 1a
  • western blot; human; loading ...; fig s1j
Patzke C, Brockmann M, Dai J, Gan K, Grauel M, Fenske P, et al. Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Cell. 2019;179:498-513.e22 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 3s1a
Kaczmarek Hájek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, et al. Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. elife. 2018;7: pubmed publisher
  • western blot; mouse; fig s1c
Liu C, Kershberg L, Wang J, Schneeberger S, Kaeser P. Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites. Cell. 2018;172:706-718.e15 pubmed publisher
  • immunocytochemistry; mouse; fig 1
  • western blot; mouse; fig 1
Bodaleo F, Montenegro Venegas C, Henríquez D, Court F, Gonzalez Billault C. Microtubule-associated protein 1B (MAP1B)-deficient neurons show structural presynaptic deficiencies in vitro and altered presynaptic physiology. Sci Rep. 2016;6:30069 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3a
Sclip A, Bacaj T, Giam L, Sudhof T. Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction. PLoS ONE. 2016;11:e0158295 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 4a
  • western blot; mouse; loading ...; fig 2b
Emanuele M, Esposito A, Camerini S, Antonucci F, Ferrara S, Seghezza S, et al. Exogenous Alpha-Synuclein Alters Pre- and Post-Synaptic Activity by Fragmenting Lipid Rafts. EBioMedicine. 2016;7:191-204 pubmed publisher
  • western blot; human
Patzke C, Acuna C, Giam L, Wernig M, Südhof T. Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation. J Exp Med. 2016;213:499-515 pubmed publisher
  • immunohistochemistry; mouse; fig 1
Gazit N, Vertkin I, Shapira I, Helm M, Slomowitz E, Sheiba M, et al. IGF-1 Receptor Differentially Regulates Spontaneous and Evoked Transmission via Mitochondria at Hippocampal Synapses. Neuron. 2016;89:583-97 pubmed publisher
  • western blot; mouse; 1:10,000
Ferreira J, Schmidt J, Rio P, Águas R, Rooyakkers A, Li K, et al. GluN2B-Containing NMDA Receptors Regulate AMPA Receptor Traffic through Anchoring of the Synaptic Proteasome. J Neurosci. 2015;35:8462-79 pubmed publisher
  • immunohistochemistry; mouse
Usui Y, Westenskow P, Kurihara T, Aguilar E, Sakimoto S, Paris L, et al. Neurovascular crosstalk between interneurons and capillaries is required for vision. J Clin Invest. 2015;125:2335-46 pubmed publisher
  • western blot; rat
Ronzitti G, Bucci G, Emanuele M, Leo D, Sotnikova T, Mus L, et al. Exogenous ?-synuclein decreases raft partitioning of Cav2.2 channels inducing dopamine release. J Neurosci. 2014;34:10603-15 pubmed publisher
  • western blot; rat
Zhao H, Kim Y, Park J, Park D, Lee S, Chang I, et al. SCAMP5 plays a critical role in synaptic vesicle endocytosis during high neuronal activity. J Neurosci. 2014;34:10085-95 pubmed publisher
  • immunocytochemistry; mouse
  • immunohistochemistry; mouse
  • western blot; mouse
  • immunocytochemistry; rat
  • immunohistochemistry; rat
  • western blot; rat
Wilhelm B, Mandad S, Truckenbrodt S, Kr hnert K, Sch fer C, Rammner B, et al. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Science. 2014;344:1023-8 pubmed publisher
  • western blot; mouse
Biesemann C, Gr Nborg M, Luquet E, Wichert S, Bernard V, Bungers S, et al. Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting. EMBO J. 2014;33:157-70 pubmed publisher
  • immunohistochemistry; mouse
Del Rio T, Nishitani A, Yu W, Goodrich L. In vivo analysis of Lrig genes reveals redundant and independent functions in the inner ear. PLoS Genet. 2013;9:e1003824 pubmed publisher
  • immunocytochemistry; rat
Agostini F, Dotti C, P rez Ca am s A, Ledesma M, Benetti F, Legname G. Prion protein accumulation in lipid rafts of mouse aging brain. PLoS ONE. 2013;8:e74244 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; fig 1
Koh J, Iwabuchi S, Harata N. Dystonia-associated protein torsinA is not detectable at the nerve terminals of central neurons. Neuroscience. 2013;253:316-29 pubmed publisher
  • western blot; mouse
Caba ero D, Baker A, Zhou S, Hargett G, Irie T, Xia Y, et al. Pain after discontinuation of morphine treatment is associated with synaptic increase of GluA4-containing AMPAR in the dorsal horn of the spinal cord. Neuropsychopharmacology. 2013;38:1472-84 pubmed publisher
  • immunohistochemistry; mouse
Liu Z, Owen T, Fang J, Zuo J. Overactivation of Notch1 signaling induces ectopic hair cells in the mouse inner ear in an age-dependent manner. PLoS ONE. 2012;7:e34123 pubmed publisher
  • immunohistochemistry; mouse
Fujita E, Tanabe Y, Imhof B, Momoi M, Momoi T. Cadm1-expressing synapses on Purkinje cell dendrites are involved in mouse ultrasonic vocalization activity. PLoS ONE. 2012;7:e30151 pubmed publisher
  • immunocytochemistry; mouse
Loske P, Boato F, Hendrix S, Piepgras J, Just I, Ahnert Hilger G, et al. Minimal essential length of Clostridium botulinum C3 peptides to enhance neuronal regenerative growth and connectivity in a non-enzymatic mode. J Neurochem. 2012;120:1084-96 pubmed publisher
  • western blot; mouse
Yeh F, Dong M, Yao J, Tepp W, Lin G, Johnson E, et al. SV2 mediates entry of tetanus neurotoxin into central neurons. PLoS Pathog. 2010;6:e1001207 pubmed publisher
  • immunocytochemistry; mouse
Dabrowski M, Aerts S, Van Hummelen P, Craessaerts K, De Moor B, Annaert W, et al. Gene profiling of hippocampal neuronal culture. J Neurochem. 2003;85:1279-88 pubmed
Ro x15f ianu F, Mihaylov S, Eder N, Martiniuc A, Claxton S, Flynn H, et al. Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration. Life Sci Alliance. 2023;6: pubmed publisher
Hoffmann Conaway S, Brockmann M, Schneider K, Annamneedi A, Rahman K, Bruns C, et al. Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice. elife. 2020;9: pubmed publisher
Esposito A, Falace A, Wagner M, Gal M, Mei D, Conti V, et al. Biallelic DMXL2 mutations impair autophagy and cause Ohtahara syndrome with progressive course. Brain. 2019;142:3876-3891 pubmed publisher
Eldahan K, Williams H, Cox D, Gollihue J, Patel S, Rabchevsky A. Paradoxical effects of continuous high dose gabapentin treatment on autonomic dysreflexia after complete spinal cord injury. Exp Neurol. 2020;323:113083 pubmed publisher
Xiao S, McKeever P, Lau A, Robertson J. Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels. Acta Neuropathol Commun. 2019;7:161 pubmed publisher
Ackermann F, Schink K, Bruns C, Izsvák Z, Hamra F, Rosenmund C, et al. Critical role for Piccolo in synaptic vesicle retrieval. elife. 2019;8: pubmed publisher
Petrov A, Lam M, Mast N, Moon J, Li Y, Maxfield E, et al. CYP46A1 Activation by Efavirenz Leads to Behavioral Improvement without Significant Changes in Amyloid Plaque Load in the Brain of 5XFAD Mice. Neurotherapeutics. 2019;: pubmed publisher
Lee J, Lee S, Ryu Y, Lee D, Kim S, Seo J, et al. Vaccinia-related kinase 2 plays a critical role in microglia-mediated synapse elimination during neurodevelopment. Glia. 2019;: pubmed publisher
Van Gool B, Storck S, Reekmans S, Lechat B, Gordts P, Pradier L, et al. LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer's Disease. Mol Neurobiol. 2019;: pubmed publisher
Fenske P, Grauel M, Brockmann M, Dorrn A, Trimbuch T, Rosenmund C. Autaptic cultures of human induced neurons as a versatile platform for studying synaptic function and neuronal morphology. Sci Rep. 2019;9:4890 pubmed publisher
Ono Y, Mori Y, Egashira Y, Sumiyama K, Takamori S. Expression of plasma membrane calcium ATPases confers Ca2+/H+ exchange in rodent synaptic vesicles. Sci Rep. 2019;9:4289 pubmed publisher
Chung J, Franklin J, Lee H. Central expression of synaptophysin and synaptoporin in nociceptive afferent subtypes in the dorsal horn. Sci Rep. 2019;9:4273 pubmed publisher
Malik A, Szydlowska K, Nizinska K, Asaro A, van Vliet E, Popp O, et al. SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology. Cell Rep. 2019;26:2792-2804.e6 pubmed publisher
de Pins B, Cifuentes Diaz C, Farah A, López Molina L, Montalban E, Sancho Balsells A, et al. Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease. J Neurosci. 2019;39:2441-2458 pubmed publisher
Milesi C, Alberici P, Pozzi B, Oldani A, Beznoussenko G, Raimondi A, et al. Redundant and nonredundant organismal functions of EPS15 and EPS15L1. Life Sci Alliance. 2019;2: pubmed publisher
Hoffmann S, Orlando M, Andrzejak E, Bruns C, Trimbuch T, Rosenmund C, et al. Light-Activated ROS Production Induces Synaptic Autophagy. J Neurosci. 2019;39:2163-2183 pubmed publisher
Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, et al. Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting. Science. 2019;363: pubmed publisher
Kindt K, SHEETS L. Transmission Disrupted: Modeling Auditory Synaptopathy in Zebrafish. Front Cell Dev Biol. 2018;6:114 pubmed publisher
Boeri J, Le Corronc H, Lejeune F, Le Bras B, Mouffle C, Angelim M, et al. Persistent Sodium Current Drives Excitability of Immature Renshaw Cells in Early Embryonic Spinal Networks. J Neurosci. 2018;38:7667-7682 pubmed publisher
Truckenbrodt S, Viplav A, Jähne S, Vogts A, Denker A, Wildhagen H, et al. Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission. EMBO J. 2018;37: pubmed publisher
Hruska M, Henderson N, Le Marchand S, Jafri H, Dalva M. Synaptic nanomodules underlie the organization and plasticity of spine synapses. Nat Neurosci. 2018;21:671-682 pubmed publisher
Farsi Z, Gowrisankaran S, Krunic M, Rammner B, Woehler A, Lafer E, et al. Clathrin coat controls synaptic vesicle acidification by blocking vacuolar ATPase activity. elife. 2018;7: pubmed publisher
Martins F, Marafona A, Pereira C, Müller T, Loosse C, Kolbe K, et al. Identification and characterization of the BRI2 interactome in the brain. Sci Rep. 2018;8:3548 pubmed publisher
Park D, Chang S. Soluble Aβ1-42 increases the heterogeneity in synaptic vesicle pool size among synapses by suppressing intersynaptic vesicle sharing. Mol Brain. 2018;11:10 pubmed publisher
Richter K, Schmutz I, Darna M, Zander J, Chavan R, Albrecht U, et al. VGLUT1 Binding to Endophilin or Intersectin1 and Dynamin Phosphorylation in a Diurnal Context. Neuroscience. 2018;371:29-37 pubmed publisher
Riemann D, Wallrafen R, Dresbach T. The Kohlschütter-Tönz syndrome associated gene Rogdi encodes a novel presynaptic protein. Sci Rep. 2017;7:15791 pubmed publisher
Nakaya N, Sultana A, Tomarev S. Impaired AMPA receptor trafficking by a double knockout of zebrafish olfactomedin1a/b. J Neurochem. 2017;143:635-644 pubmed publisher
Mass E, Jacome Galarza C, Blank T, Lazarov T, Durham B, Ozkaya N, et al. A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease. Nature. 2017;549:389-393 pubmed publisher
Terni B, Pacciolla P, Masanas H, Gorostiza P, Llobet A. Tight temporal coupling between synaptic rewiring of olfactory glomeruli and the emergence of odor-guided behavior in Xenopus tadpoles. J Comp Neurol. 2017;525:3769-3783 pubmed publisher
Bröker Lai J, Kollewe A, Schindeldecker B, Pohle J, Nguyen Chi V, Mathar I, et al. Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory. EMBO J. 2017;36:2770-2789 pubmed publisher
Zhang S, Masuyer G, Zhang J, Shen Y, Lundin D, Henriksson L, et al. Identification and characterization of a novel botulinum neurotoxin. Nat Commun. 2017;8:14130 pubmed publisher
Schenck S, Kunz L, Sahlender D, Pardon E, Geertsma E, Savtchouk I, et al. Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport. Biochemistry. 2017;56:3962-3971 pubmed publisher
Daniel J, Cooper B, Palvimo J, Zhang F, Brose N, Tirard M. Analysis of SUMO1-conjugation at synapses. elife. 2017;6: pubmed publisher
Su Y, Yuan Y, Feng S, Ma S, Wang Y. High frequency stimulation induces sonic hedgehog release from hippocampal neurons. Sci Rep. 2017;7:43865 pubmed publisher
Espuny Camacho I, Arranz A, Fiers M, Snellinx A, Ando K, Munck S, et al. Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain. Neuron. 2017;93:1066-1081.e8 pubmed publisher
Okerlund N, Schneider K, Leal Ortiz S, Montenegro Venegas C, Kim S, Garner L, et al. Bassoon Controls Presynaptic Autophagy through Atg5. Neuron. 2017;93:897-913.e7 pubmed publisher
Liu T, Li H, Hong W, Han W. Brefeldin A-inhibited guanine nucleotide exchange protein 3 is localized in lysosomes and regulates GABA signaling in hippocampal neurons. J Neurochem. 2016;139:748-756 pubmed publisher
Grauel M, Maglione M, Reddy Alla S, Willmes C, Brockmann M, Trimbuch T, et al. RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses. Proc Natl Acad Sci U S A. 2016;113:11615-11620 pubmed
Acuna C, Liu X, Sudhof T. How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs. Neuron. 2016;91:792-807 pubmed publisher
Adolf A, Leondaritis G, Rohrbeck A, Eickholt B, Just I, Ahnert Hilger G, et al. The intermediate filament protein vimentin is essential for axonotrophic effects of Clostridium botulinum C3 exoenzyme. J Neurochem. 2016;139:234-244 pubmed publisher
Amin H, Maccione A, Marinaro F, Zordan S, Nieus T, Berdondini L. Electrical Responses and Spontaneous Activity of Human iPS-Derived Neuronal Networks Characterized for 3-month Culture with 4096-Electrode Arrays. Front Neurosci. 2016;10:121 pubmed publisher
Rajappa R, Gauthier Kemper A, Böning D, Hüve J, Klingauf J. Synaptophysin 1 Clears Synaptobrevin 2 from the Presynaptic Active Zone to Prevent Short-Term Depression. Cell Rep. 2016;14:1369-1381 pubmed publisher
Koo S, Kochlamazashvili G, Rost B, Puchkov D, Gimber N, Lehmann M, et al. Vesicular Synaptobrevin/VAMP2 Levels Guarded by AP180 Control Efficient Neurotransmission. Neuron. 2015;88:330-44 pubmed publisher
Patzke C, Han Y, Covy J, Yi F, Maxeiner S, Wernig M, et al. Analysis of conditional heterozygous STXBP1 mutations in human neurons. J Clin Invest. 2015;125:3560-71 pubmed publisher
Cheng C, Wang W, Huang C, Du P, Yang J, Tsaur M. Coexpression of auxiliary subunits KChIP and DPPL in potassium channel Kv4-positive nociceptors and pain-modulating spinal interneurons. J Comp Neurol. 2016;524:846-73 pubmed publisher
Wake H, Ortiz F, Woo D, Lee P, Angulo M, Fields R. Nonsynaptic junctions on myelinating glia promote preferential myelination of electrically active axons. Nat Commun. 2015;6:7844 pubmed publisher
Meneghello G, Verheyen A, van Ingen M, Kuijlaars J, Tuefferd M, Van den Wyngaert I, et al. Evaluation of established human iPSC-derived neurons to model neurodegenerative diseases. Neuroscience. 2015;301:204-12 pubmed publisher
Jadhav S, Katina S, Kovac A, Kazmerova Z, Novak M, Zilka N. Truncated tau deregulates synaptic markers in rat model for human tauopathy. Front Cell Neurosci. 2015;9:24 pubmed publisher
Binotti B, Pavlos N, Riedel D, Wenzel D, Vorbrüggen G, Schalk A, et al. The GTPase Rab26 links synaptic vesicles to the autophagy pathway. elife. 2015;4:e05597 pubmed publisher
Mollinari C, Racaniello M, Berry A, Pieri M, de Stefano M, Cardinale A, et al. miR-34a regulates cell proliferation, morphology and function of newborn neurons resulting in improved behavioural outcomes. Cell Death Dis. 2015;6:e1622 pubmed publisher
Vogl C, Tanifuji S, Danis B, Daniëls V, Foerch P, Wolff C, et al. Synaptic vesicle glycoprotein 2A modulates vesicular release and calcium channel function at peripheral sympathetic synapses. Eur J Neurosci. 2015;41:398-409 pubmed publisher
Rodriguez Espinosa N, Fernandez Espejo E. Effects of acute and repeated cocaine on markers for neural plasticity within the mesolimbic system in rats. Psychopharmacology (Berl). 2015;232:57-62 pubmed publisher
Calton M, Lee D, Sundaresan S, Mendus D, Leu R, Wangsawihardja F, et al. A lack of immune system genes causes loss in high frequency hearing but does not disrupt cochlear synapse maturation in mice. PLoS ONE. 2014;9:e94549 pubmed publisher
Yu W, Appler J, Kim Y, Nishitani A, Holt J, Goodrich L. A Gata3-Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing. elife. 2013;2:e01341 pubmed publisher
Bonnet S, Akad D, Samaddar T, Liu Y, Huang X, Dong Y, et al. Synaptic state-dependent functional interplay between postsynaptic density-95 and synapse-associated protein 102. J Neurosci. 2013;33:13398-409 pubmed publisher
Kempf C, Staudt T, Bingen P, Horstmann H, Engelhardt J, Hell S, et al. Tissue multicolor STED nanoscopy of presynaptic proteins in the calyx of Held. PLoS ONE. 2013;8:e62893 pubmed publisher
Ahmed S, Holt M, Riedel D, Jahn R. Small-scale isolation of synaptic vesicles from mammalian brain. Nat Protoc. 2013;8:998-1009 pubmed publisher
Martineau M, Shi T, Puyal J, Knolhoff A, Dulong J, Gasnier B, et al. Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission. J Neurosci. 2013;33:3413-23 pubmed publisher
Bouyer K, Simerly R. Neonatal leptin exposure specifies innervation of presympathetic hypothalamic neurons and improves the metabolic status of leptin-deficient mice. J Neurosci. 2013;33:840-51 pubmed publisher
Wei S, Soh S, Qiu W, Yang W, Seah C, Guo J, et al. Seipin regulates excitatory synaptic transmission in cortical neurons. J Neurochem. 2013;124:478-89 pubmed publisher
Huupponen J, Molchanova S, Lauri S, Taira T. Ongoing intrinsic synchronous activity is required for the functional maturation of CA3-CA1 glutamatergic synapses. Cereb Cortex. 2013;23:2754-64 pubmed publisher
Ricciardi S, Ungaro F, Hambrock M, Rademacher N, Stefanelli G, Brambilla D, et al. CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons. Nat Cell Biol. 2012;14:911-23 pubmed publisher
Kwon S, Chapman E. Glycosylation is dispensable for sorting of synaptotagmin 1 but is critical for targeting of SV2 and synaptophysin to recycling synaptic vesicles. J Biol Chem. 2012;287:35658-68 pubmed publisher
Su J, Stenbjorn R, Gorse K, Su K, Hauser K, Ricard Blum S, et al. Target-derived matricryptins organize cerebellar synapse formation through ?3?1 integrins. Cell Rep. 2012;2:223-30 pubmed publisher
Vasileva M, Horstmann H, Geumann C, Gitler D, Kuner T. Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission. Eur J Neurosci. 2012;36:3005-20 pubmed publisher
Schmeisser M, Baumann B, Johannsen S, Vindedal G, Jensen V, Hvalby Ø, et al. I?B kinase/nuclear factor ?B-dependent insulin-like growth factor 2 (Igf2) expression regulates synapse formation and spine maturation via Igf2 receptor signaling. J Neurosci. 2012;32:5688-703 pubmed publisher
Raingo J, Khvotchev M, Liu P, Darios F, Li Y, Ramirez D, et al. VAMP4 directs synaptic vesicles to a pool that selectively maintains asynchronous neurotransmission. Nat Neurosci. 2012;15:738-45 pubmed publisher
Blum F, Chen C, Kroken A, Barbieri J. Tetanus toxin and botulinum toxin a utilize unique mechanisms to enter neurons of the central nervous system. Infect Immun. 2012;80:1662-9 pubmed publisher
Görlich A, Wolf M, Zimmermann A, Gurniak C, Al Banchaabouchi M, Sassoè Pognetto M, et al. N-cofilin can compensate for the loss of ADF in excitatory synapses. PLoS ONE. 2011;6:e26789 pubmed publisher
Herzog E, Nadrigny F, Silm K, Biesemann C, Helling I, Bersot T, et al. In vivo imaging of intersynaptic vesicle exchange using VGLUT1 Venus knock-in mice. J Neurosci. 2011;31:15544-59 pubmed publisher
Barth J, Zimmermann H, Volknandt W. SV31 is a Zn2+-binding synaptic vesicle protein. J Neurochem. 2011;118:558-70 pubmed publisher
Gomes J, Lobo A, Melo C, Inácio A, Takano J, Iwata N, et al. Cleavage of the vesicular GABA transporter under excitotoxic conditions is followed by accumulation of the truncated transporter in nonsynaptic sites. J Neurosci. 2011;31:4622-35 pubmed publisher
Treppmann P, Brunk I, Afube T, Richter K, Ahnert Hilger G. Neurotoxic phospholipases directly affect synaptic vesicle function. J Neurochem. 2011;117:757-64 pubmed publisher
Hoopmann P, Punge A, Barysch S, Westphal V, B ckers J, Opazo F, et al. Endosomal sorting of readily releasable synaptic vesicles. Proc Natl Acad Sci U S A. 2010;107:19055-60 pubmed publisher
Brunk I, Sanchis Segura C, Blex C, Perreau Lenz S, Bilbao A, Spanagel R, et al. Amphetamine regulates NR2B expression in Go2? knockout mice and thereby sustains behavioral sensitization. J Neurochem. 2010;115:234-46 pubmed publisher
Lanore F, Blanchet C, Fejtova A, Pinheiro P, Richter K, Balschun D, et al. Impaired development of hippocampal mossy fibre synapses in mouse mutants for the presynaptic scaffold protein Bassoon. J Physiol. 2010;588:2133-45 pubmed publisher
Geumann U, Schäfer C, Riedel D, Jahn R, Rizzoli S. Synaptic membrane proteins form stable microdomains in early endosomes. Microsc Res Tech. 2010;73:606-17 pubmed publisher
Reim K, Regus Leidig H, Ammermüller J, El Kordi A, Radyushkin K, Ehrenreich H, et al. Aberrant function and structure of retinal ribbon synapses in the absence of complexin 3 and complexin 4. J Cell Sci. 2009;122:1352-61 pubmed publisher
Martens H, Weston M, Boulland J, Grønborg M, Grosche J, Kacza J, et al. Unique luminal localization of VGAT-C terminus allows for selective labeling of active cortical GABAergic synapses. J Neurosci. 2008;28:13125-31 pubmed publisher
Jockusch W, Speidel D, Sigler A, S rensen J, Varoqueaux F, Rhee J, et al. CAPS-1 and CAPS-2 are essential synaptic vesicle priming proteins. Cell. 2007;131:796-808 pubmed publisher
Smith R, Klein P, Koc Schmitz Y, Waldvogel H, Faull R, Brundin P, et al. Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease. J Neurochem. 2007;103:115-23 pubmed
Herzog E, Takamori S, Jahn R, Brose N, Wojcik S. Synaptic and vesicular co-localization of the glutamate transporters VGLUT1 and VGLUT2 in the mouse hippocampus. J Neurochem. 2006;99:1011-8 pubmed
Andrews Zwilling Y, Kawabe H, Reim K, Varoqueaux F, Brose N. Binding to Rab3A-interacting molecule RIM regulates the presynaptic recruitment of Munc13-1 and ubMunc13-2. J Biol Chem. 2006;281:19720-31 pubmed
Xiang Y, Dong H, Wan Y, Li J, Yee A, Yang B, et al. Versican G3 domain regulates neurite growth and synaptic transmission of hippocampal neurons by activation of epidermal growth factor receptor. J Biol Chem. 2006;281:19358-68 pubmed
Yelamanchili S, Pendyala G, Brunk I, Darna M, Albrecht U, Ahnert Hilger G. Differential sorting of the vesicular glutamate transporter 1 into a defined vesicular pool is regulated by light signaling involving the clock gene Period2. J Biol Chem. 2006;281:15671-9 pubmed
Morciano M, Burré J, Corvey C, Karas M, Zimmermann H, Volknandt W. Immunoisolation of two synaptic vesicle pools from synaptosomes: a proteomics analysis. J Neurochem. 2005;95:1732-45 pubmed
Reim K, Wegmeyer H, Brandst tter J, Xue M, Rosenmund C, Dresbach T, et al. Structurally and functionally unique complexins at retinal ribbon synapses. J Cell Biol. 2005;169:669-80 pubmed publisher
Wan L, Almers W, Chen W. Two ribeye genes in teleosts: the role of Ribeye in ribbon formation and bipolar cell development. J Neurosci. 2005;25:941-9 pubmed publisher
Rüder C, Reimer T, Delgado Martinez I, Hermosilla R, Engelsberg A, Nehring R, et al. EBAG9 adds a new layer of control on large dense-core vesicle exocytosis via interaction with Snapin. Mol Biol Cell. 2005;16:1245-57 pubmed
Lazzell D, Belizaire R, Thakur P, Sherry D, Janz R. SV2B regulates synaptotagmin 1 by direct interaction. J Biol Chem. 2004;279:52124-31 pubmed publisher
Reisinger C, Yelamanchili S, Hinz B, Mitter D, Becher A, Bigalke H, et al. The synaptophysin/synaptobrevin complex dissociates independently of neuroexocytosis. J Neurochem. 2004;90:1-8 pubmed publisher
Sidi S, Busch Nentwich E, Friedrich R, Schoenberger U, Nicolson T. gemini encodes a zebrafish L-type calcium channel that localizes at sensory hair cell ribbon synapses. J Neurosci. 2004;24:4213-23 pubmed
Wojcik S, Rhee J, Herzog E, Sigler A, Jahn R, Takamori S, et al. An essential role for vesicular glutamate transporter 1 (VGLUT1) in postnatal development and control of quantal size. Proc Natl Acad Sci U S A. 2004;101:7158-63 pubmed
Knoch K, Bergert H, Borgonovo B, Saeger H, Altkr ger A, Verkade P, et al. Polypyrimidine tract-binding protein promotes insulin secretory granule biogenesis. Nat Cell Biol. 2004;6:207-14 pubmed
Ferguson S, Savchenko V, Apparsundaram S, Zwick M, Wright J, Heilman C, et al. Vesicular localization and activity-dependent trafficking of presynaptic choline transporters. J Neurosci. 2003;23:9697-709 pubmed
Morgenthaler F, Knott G, Floyd Sarria J, Wang X, Staple J, Catsicas S, et al. Morphological and molecular heterogeneity in release sites of single neurons. Eur J Neurosci. 2003;17:1365-74 pubmed
von Kriegstein K, Schmitz F. The expression pattern and assembly profile of synaptic membrane proteins in ribbon synapses of the developing mouse retina. Cell Tissue Res. 2003;311:159-73 pubmed publisher
Von Kriegstein K, Schmitz F, Link E, S dhof T. Distribution of synaptic vesicle proteins in the mammalian retina identifies obligatory and facultative components of ribbon synapses. Eur J Neurosci. 1999;11:1335-48 pubmed
Becher A, Drenckhahn A, Pahner I, Margittai M, Jahn R, Ahnert Hilger G. The synaptophysin-synaptobrevin complex: a hallmark of synaptic vesicle maturation. J Neurosci. 1999;19:1922-31 pubmed
Jahn R, Schiebler W, Ouimet C, Greengard P. A 38,000-dalton membrane protein (p38) present in synaptic vesicles. Proc Natl Acad Sci U S A. 1985;82:4137-41 pubmed
product information
Cat. Nr. :
101 011
Antigen :
Synaptophysin 1
Synonyms :
p38-1, Synaptophysin1
Host Species :
mouse
Tpye :
monoclonal
Form :
purified IgG
Cell Line :
07. Feb
Subtype :
IgG1
Immunogen :
Recombinant protein corresponding to AA 1 to 307 from rat Synaptophysin1 (UniProt Id: P07825)
Reactivity :
human, rat, mouse, mammals, zebrafish, other vertebrates
WB :
WB
IP :
IP
ICC :
ICC
IHC :
IHC
IHC P :
IHC-P
EM :
EM
ELISA :
ELISA
KO :
yes
KD :
yes
Quantity :
50 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany