product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
Synaptophysin 1
catalog :
101 002
quantity :
200 µl
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine, Xenopus laevis
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - free floating section
more info or order :
citations: 29
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; rat; loading ...
Ivanova D, Dobson K, Gajbhiye A, Davenport E, Hacker D, Ultanir S, et al. Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes. Sci Adv. 2021;7: pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:200; loading ...; fig s2f
Bączyk M, Alami N, Delestrée N, Martinot C, Tang L, Commisso B, et al. Synaptic restoration by cAMP/PKA drives activity-dependent neuroprotection to motoneurons in ALS. J Exp Med. 2020;217: pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 2b
Smith H, Freeman O, Butcher A, Holmqvist S, Humoud I, Schätzl T, et al. Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration. Neuron. 2020;: pubmed publisher
  • immunocytochemistry; human; fig s4d
Wegmann R, Neri M, Schuierer S, Bilican B, Hartkopf H, Nigsch F, et al. CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data. Genome Biol. 2019;20:142 pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig 5f
Bieri G, Brahic M, Bousset L, Couthouis J, Kramer N, Ma R, et al. LRRK2 modifies α-syn pathology and spread in mouse models and human neurons. Acta Neuropathol. 2019;137:961-980 pubmed publisher
  • western blot; mouse; fig 6
Dragich J, Kuwajima T, Hirose Ikeda M, Yoon M, Eenjes E, Bosco J, et al. Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain. elife. 2016;5: pubmed publisher
  • immunohistochemistry; Xenopus laevis; 1:500; loading ...; tbl 1
Messina A, Bridi S, Bozza A, Bozzi Y, Baudet M, Casarosa S. Noggin 1 overexpression in retinal progenitors affects bipolar cell generation. Int J Dev Biol. 2016;60:151-7 pubmed publisher
Chantranupong L, Saulnier J, Wang W, Jones D, Pacold M, Sabatini B. Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain. elife. 2020;9: pubmed publisher
Simbriger K, Amorim I, Chalkiadaki K, Lach G, Jafarnejad S, Khoutorsky A, et al. Monitoring translation in synaptic fractions using a ribosome profiling strategy. J Neurosci Methods. 2020;329:108456 pubmed publisher
Piriya Ananda Babu L, Wang H, Eguchi K, Guillaud L, Takahashi T. Microtubule and Actin Differentially Regulate Synaptic Vesicle Cycling to Maintain High-frequency Neurotransmission. J Neurosci. 2019;: pubmed publisher
Bouybayoune I, Comerio L, Pasetto L, Bertani I, Bonetto V, Chiesa R. Cyclophillin A deficiency accelerates RML-induced prion disease. Neurobiol Dis. 2019;130:104498 pubmed publisher
McKenzie C, Spanova M, Johnson A, Kainrath S, Zheden V, Sitte H, et al. Isolation of synaptic vesicles from genetically engineered cultured neurons. J Neurosci Methods. 2018;312:114-121 pubmed publisher
Alpar A, Zahola P, Hanics J, Hevesi Z, Korchynska S, Benevento M, et al. Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress. EMBO J. 2018;37: pubmed publisher
Perez M, Cartarozzi L, Chiarotto G, Oliveira S, Guimarães F, Oliveira A. Neuronal preservation and reactive gliosis attenuation following neonatal sciatic nerve axotomy by a fluorinated cannabidiol derivative. Neuropharmacology. 2018;140:201-208 pubmed publisher
Rodríguez Muela N, Parkhitko A, Grass T, Gibbs R, Norabuena E, Perrimon N, et al. Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes. J Clin Invest. 2018;128:3008-3023 pubmed publisher
Richter M, Murtaza N, Scharrenberg R, White S, Johanns O, Walker S, et al. Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling. Mol Psychiatry. 2018;: pubmed publisher
Lautenschläger J, Stephens A, Fusco G, Ströhl F, Curry N, Zacharopoulou M, et al. C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction. Nat Commun. 2018;9:712 pubmed publisher
So E, Mitchell J, Memmi C, Chennell G, Vizcay Barrena G, Allison L, et al. Mitochondrial abnormalities and disruption of the neuromuscular junction precede the clinical phenotype and motor neuron loss in hFUSWT transgenic mice. Hum Mol Genet. 2018;27:463-474 pubmed publisher
Frahm S, Melis V, Horsley D, Rickard J, Riedel G, Fadda P, et al. Alpha-Synuclein transgenic mice, h-?-SynL62, display ?-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease. Behav Brain Res. 2018;339:153-168 pubmed publisher
Laperchia C, Imperatore R, Azeez I, Del Gallo F, Bertini G, Grassi Zucconi G, et al. The excitatory/inhibitory input to orexin/hypocretin neuron soma undergoes day/night reorganization. Brain Struct Funct. 2017;222:3847-3859 pubmed publisher
Fasano C, Rocchetti J, Pietrajtis K, Zander J, Manseau F, Sakae D, et al. Regulation of the Hippocampal Network by VGLUT3-Positive CCK- GABAergic Basket Cells. Front Cell Neurosci. 2017;11:140 pubmed publisher
Okerlund N, Schneider K, Leal Ortiz S, Montenegro Venegas C, Kim S, Garner L, et al. Bassoon Controls Presynaptic Autophagy through Atg5. Neuron. 2017;93:897-913.e7 pubmed publisher
Ripamonti S, Ambrozkiewicz M, Guzzi F, Gravati M, Biella G, Bormuth I, et al. Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons. elife. 2017;6: pubmed publisher
Formoso K, García M, Frasch A, Scorticati C. Evidence for a role of glycoprotein M6a in dendritic spine formation and synaptogenesis. Mol Cell Neurosci. 2016;77:95-104 pubmed publisher
Bhattacharya S, Herrera Molina R, Sabanov V, Ahmed T, Iscru E, Stöber F, et al. Genetically Induced Retrograde Amnesia of Associative Memories After Neuroplastin Ablation. Biol Psychiatry. 2017;81:124-135 pubmed publisher
Valente P, Castroflorio E, Rossi P, Fadda M, Sterlini B, Cervigni R, et al. PRRT2 Is a Key Component of the Ca(2+)-Dependent Neurotransmitter Release Machinery. Cell Rep. 2016;15:117-131 pubmed publisher
Gordon S, Harper C, Smillie K, Cousin M. A Fine Balance of Synaptophysin Levels Underlies Efficient Retrieval of Synaptobrevin II to Synaptic Vesicles. PLoS ONE. 2016;11:e0149457 pubmed publisher
Rajappa R, Gauthier Kemper A, Böning D, Hüve J, Klingauf J. Synaptophysin 1 Clears Synaptobrevin 2 from the Presynaptic Active Zone to Prevent Short-Term Depression. Cell Rep. 2016;14:1369-1381 pubmed publisher
Ferrero J, Ramírez Franco J, Martín R, Bartolomé Martín D, Torres M, Sánchez Prieto J. Cross-talk between metabotropic glutamate receptor 7 and beta adrenergic receptor signaling at cerebrocortical nerve terminals. Neuropharmacology. 2016;101:412-25 pubmed publisher
product information
Cat. Nr. :
101 002
Antigen :
Synaptophysin 1
Synonyms :
p38-1, Synaptophysin1
Host Species :
rabbit
Tpye :
polyclonal
Form :
antiserum
Immunogen :
Synthetic peptide corresponding to AA 301 to 313 from human Synaptophysin1 (UniProt Id: P08247)
Reactivity :
human, rat, mouse, hamster, cow, chicken, frog, zebrafish
WB :
WB
IP :
IP
ICC :
ICC
IHC :
IHC
IHC P :
IHC-P
EM :
EM
ELISA :
ELISA
Quantity :
200 µl
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany