product summary
Loading...
company name :
StressMarq Biosciences
product type :
protein
product name :
Tau-383 (0N4R) Wild-Type Pre-formed Fibrils
catalog :
SPR-510
quantity :
100 µg
more info or order :
image
image 1 :
Representative TEM image of E. coli-expressed Tau 0N4R Pre-Formed Fibrils (PFFs), 200nm scale. Negative stain transmission electron microscopy images of SPR-510 acquired at 80 Kv on carbon coated 400 mesh copper grids using phosphotungstic acid and uranyl acetate stain.
image 2 :
ThT-positive signal of human Tau-383 (0N4R) Pre-formed Fibrils (SPR-510) compared to monomers (SPR-509). Samples incubated with 25 uM ThT and read with an XPS Microplate Reader at 450nmex/485nmem.
image 3 :
Sedimentation assay on E. coli expressed hTau-383 (0N4R) PFFs. Samples were spun down at 15,000 x g, washed, and then spun down again. Fibril samples are prepared in denaturing conditions prior to running on the gel. SDS-PAGE analysis on a 12% Bis-Tris gel shows that the majority of the fibril is insoluble.
product information
Catalog No :
SPR-510
Product Name :
Tau-383 (0N4R) Wild-Type Pre-formed Fibrils
Description :
Human Recombinant Tau-383 (0N4R) Wild-Type Pre-formed Fibrils
Size :
100 µg
Research Area(s) :
Neuroscience Neurodegeneration Alzheimer's Disease Tangles & Tau
Alternative Name(s) :
Tau-D, Tau 383
Category :
Protein
Nature :
Recombinant
Swiss-Prot :
P10636-6
Applications :
WB SDS PAGE In vitro Assay
Species :
Human
Expression System :
E. coli
Protein Length :
383 aa
Amino Acid Sequence :
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDT
DAGLKAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTG
SDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKT
PPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPS
LPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDL
KNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCG
SKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHK
PGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKK
IETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLS
NVSSTGSIDMVDSPQLATLADEVSASLAKQGL
DAGLKAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTG
SDDKKAKGADGKTKIATPRGAAPPGQKGQANATRIPAKT
PPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPS
LPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDL
KNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCG
SKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHK
PGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKK
IETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLS
NVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Purity :
>95% as per SDS-PAGE, >80% as per A260/A280
Protein Size :
40.007 kDa
Conjugate :
No Tag
more info or order :
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.
browse more products
questions and comments