product summary
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company name :
StressMarq Biosciences
product type :
protein
product name :
Tau Truncated Fragment (AA297-391) (dGAE) Monomers
catalog :
SPR-444
quantity :
100 µg
more info or order :
StressMarq Biosciences product webpage
citations: 2
Reference
Ondrejcak T, Hu N, Coode E, Campbell T, Corbett G, Doykov I, et al. Synaptotoxic effects of extracellular tau are mediated by its microtubule-binding region. Acta Neuropathol. 2025;149:56 pubmed publisher
Ungerleider K, Beck J, Lissa D, Turnquist C, Horikawa I, Harris B, et al. Astrocyte senescence and SASP in neurodegeneration: tau joins the loop. Cell Cycle. 2021;20:752-764 pubmed publisher
image
image 1 :
StressMarq Biosciences SPR-444 image 1
Thioflavin T is a fluorescent dye that binds to beta sheet-rich structures, such as those in tau fibrils. Upon binding, the emission spectrum of the dye experiences a red-shift and increased fluorescence intensity. Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) over time when truncated tau fragment (AA297-391) (dGAE) monomer is combined with truncated tau fragment (AA297-391) (dGAE) preformed fibrils (Type 1).
product information
Catalog No :
SPR-444
Product Name :
Tau Truncated Fragment (AA297-391) (dGAE) Monomers
Description :
Human Recombinant Truncated Tau Fragment (AA297-391) (dGAE) Protein Monomers
Size :
100 µg
Research Area(s) :
Alzheimer's Disease Axon Markers Cell Markers Cell Signaling Cytoskeleton Microtubules MT Associated Proteins Neurodegeneration Neuron Markers Neuroscience Tangles & Tau
Alternative Name(s) :
Tau monomer, Tau protein monomer, Tau protein, microtubule-associated protein Tau, MAPT, MAP, microtubule-associated protein, Truncated Tau Protein Monomer, Paired Helical Filament-Tau, Phf-Tau, Neurofibrillary Tangle Protein, G Protein Beta1/Gamma2 Subunit-Interacting Factor 1, Isoform 2, tubulin-associated unit, 95-amino acid Tau protein fragment, Truncated Tau Protein
Category :
Protein
Nature :
Recombinant
Accession Number :
NP_005901.2
Swiss-Prot :
P10636
Applications :
WB SDS-PAGE In vivo assay In vitro assay
Species :
Human
Expression System :
E. coli
Protein Length :
Fragment
Amino Acid Sequence :
IKHVPGGGSV QIVYKPVDLS KVTSKCGSLG NIHHKPGGGQ VEVKSEKLDF KDRVQSKIGS LDNITHVPGG GNKKIETHKL TFRENAKAKT DHGAE
Purity :
>95%
Protein Size :
10.165 kDa
Conjugate :
No tag
Cellular Localization :
Cytoplasm Axolemma Axolemma Plasma Membrane Axon Cell Body Cell membrane Cytoplasmic Ribonucleoprotein Granule Cytoplasmic Side Cytoskeleton Cytosol Dendrite Growth cone Microtubule Microtubule Associated Complex Neurofibrillary Tangle Neuronal Cell Body Nuclear Periphery Nuclear Speck Nucleus Peripheral membrane protein Plasma Membrane Tubulin Complex
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.