product summary
Loading...
company name :
StressMarq Biosciences
product type :
protein
product name :
Tau (K18) P301L Mutant Pre-formed Fibrils
catalog :
SPR-330
quantity :
100 µg
more info or order :
StressMarq Biosciences product webpage
citations: 7
Reference
Desai A, Zupancic J, Trzeciakiewicz H, Gerson J, DuBois K, Skinner M, et al. Facile generation of drug-like conformational antibodies specific for amyloid fibrils. Nat Chem Biol. 2025;21:916-925 pubmed publisher
Yu L, Wang H, Yao Q, Li K, Qu L, Tang B, et al. Thonningianin A from Penthorum chinense Pursh as a targeted inhibitor of Alzheimer's disease-related β-amyloid and Tau proteins. Phytother Res. 2024;38:4815-4831 pubmed publisher
Batenburg K, Rohde S, Cornelissen Steijger P, Breeuwsma N, Heine V, Scheper W. A Human Neuron/Astrocyte Co-culture to Model Seeded and Spontaneous Intraneuronal Tau Aggregation. Curr Protoc. 2023;3:e900 pubmed publisher
Desai A, Zupancic J, Trzeciakiewicz H, Gerson J, DuBois K, Skinner M, et al. Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils. bioRxiv. 2023;: pubmed publisher
Tan J, Finkel T. A phosphoinositide signalling pathway mediates rapid lysosomal repair. Nature. 2022;609:815-821 pubmed publisher
Sandusky Beltran L, Kovalenko A, Placides D, Ratnasamy K, Ma C, Hunt J, et al. Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology. J Clin Invest. 2021;131: pubmed publisher
Yang C, Luo Y, Guo K, Zheng C, Li L, Zhang L. Cornel Iridoid Glycoside Regulates Modification of Tau and Alleviates Synaptic Abnormalities in Aged P301S Mice. Curr Med Sci. 2020;40:1040-1046 pubmed publisher
product information
Catalog No :
SPR-330
Product Name :
Tau (K18) P301L Mutant Pre-formed Fibrils
Description :
Human Recombinant Tau (K18) P301L Mutant PFFs
Size :
100 µg
Research Area(s) :
Alzheimer's Disease Axon Markers Cell Markers Cell Signaling Cytoskeleton Microtubules MT Associated Proteins Neurodegeneration Neuron Markers Neuroscience Tangles & Tau
Alternative Name(s) :
Tau PFFs, Tau PFF, Tau protein Pre-formed Fibrils, Tau aggregates, microtubule-associated protein Tau, MAPT, MAP, microtubule-associated protein, Paired Helical Filament-Tau, Phf-Tau, Neurofibrillary Tangle Protein, G Protein Beta1/Gamma2 Subunit-Interacting Factor 1, Isoform 4, tubulin-associated unit
Category :
Protein
Nature :
Recombinant
Swiss-Prot :
P10636
Applications :
WB SDS-PAGE In vivo assay In vitro assay
Species :
Human
Expression System :
E. coli
Protein Length :
Partial
Amino Acid Sequence :
SRLQTAPVPM PDLKNVKSKI GSTENLKHQP GGGKVQIINK KLDLSNVQSK CGSKDNIKHVLGGGSVQIVY KPVDLSKVTS KCGSLGNIHH KPGGGQVEVK SEKLDFKDRV QSKIGSLDNI THVPGGGNKK IETHKLTFRE
Purity :
>95%
Protein Size :
~15.1 kDa
Conjugate :
No tag
Cellular Localization :
Cytoplasm Axolemma Axolemma Plasma Membrane Axon Cell Body Cell membrane Cytoplasmic Ribonucleoprotein Granule Cytoplasmic Side Cytoskeleton Cytosol Dendrite Growth cone Microtubule Microtubule Associated Complex Neurofibrillary Tangle Neuronal Cell Body Nuclear Periphery Nuclear Speck Nucleus Peripheral membrane protein Plasma Membrane Tubulin Complex
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.