product summary
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company name :
StressMarq Biosciences
product type :
protein
product name :
Alpha Synuclein Preformed Fibrils (Type 1)
catalog :
SPR-322B
quantity :
100 µg
price :
347 USD
more info or order :
StressMarq Biosciences product webpage
citations: 2
Reference
Cho E, Park J, Kim K, Kim M, Cho S. Reelin Alleviates Mesenchymal Stem Cell Senescence and Reduces Pathological α-Synuclein Expression in an In Vitro Model of Parkinson's Disease. Genes (Basel). 2021;12: pubmed publisher
Yakubu U, Morano K. Suppression of aggregate and amyloid formation by a novel intrinsically disordered region in metazoan Hsp110 chaperones. J Biol Chem. 2021;296:100567 pubmed publisher
product information
Catalog No :
SPR-322B
Product Name :
Alpha Synuclein Preformed Fibrils (Type 1)
Product Type :
Protein
Nature :
Recombinant
Species :
Human
Conjugate :
No tag
Size :
100 µg
List Price USD :
347 USD
Description :
Active Human Recombinant Alpha Synuclein Preformed Fibrils (Type 1)
Applications :
WB SDS-PAGE In vivo assay In vitro assay
Alternative Name(s) :
Active Alpha synuclein PFFs, Active Alpha synuclein aggregates, Alpha synuclein PFF, Active Alpha synuclein protein aggregates, Active Alpha synuclein aggregates, Active Alpha-synuclein protein, Non-A beta component of AD amyloid protein, Non-A4 component of amyloid precursor protein, NACP protein, SNCA protein, NACP protein, PARK1 protein, SYN protein, Parkinson's disease familial 1 Protein, Active Alpha synuclein protein seed
Cellular Localization :
Cytoplasm Membrane Nucleus
Purity :
>95%
Purification :
Ion-exchange Purified
Accession Number :
NP_000336.1
Swiss-Prot :
P37840
Biological Activity :
Endogenous alpha-synuclein phosphorylation. 100 µM alpha synuclein protein monomer (SPR-321) seeded with 10 uM alpha synuclein protein PFF (SPR-322) in 25 µM Thioflavin T (PBS pH 7.4, 100 µl reaction volume) generated a fluorescence intensity of 13,000 Relative Fluorescence Units after incubation at 37°C with shaking at 600 rpm. Fluorescence was measured by excitation at 450 nm and emission at 485 nm on a Molecular Devices Gemini XPS microplate reader.
Expression System :
E. coli
Protein Size :
~14.46 kDa
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.