product summary
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company name :
StressMarq Biosciences
product type :
protein
product name :
HOP Protein
catalog :
SPR-302
quantity :
50 µg
more info or order :
StressMarq Biosciences product webpage
citations: 4
Reference
Zaiter S, Huo Y, Tiew F, Gestwicki J, McAlpine S. Designing de Novo Small Molecules That Control Heat Shock Protein 70 (Hsp70) and Heat Shock Organizing Protein (HOP) within the Chaperone Protein-Folding Machinery. J Med Chem. 2019;62:742-761 pubmed publisher
Koay Y, Richardson N, Zaiter S, Kho J, Nguyen S, Tran D, et al. Hitting a Moving Target: How Does an N-Methyl Group Impact Biological Activity?. ChemMedChem. 2016;11:881-92 pubmed publisher
Wahyudi H, Wang Y, McAlpine S. Dimerization of a heat shock protein 90 inhibitor enhances inhibitory activity. Org Biomol Chem. 2014;12:765-73 pubmed publisher
Willmer T, Contu L, Blatch G, Edkins A. Knockdown of Hop downregulates RhoC expression, and decreases pseudopodia formation and migration in cancer cell lines. Cancer Lett. 2013;328:252-60 pubmed publisher
image
image 1 :
StressMarq Biosciences SPR-302 image 1
SDS-PAGE of his-tagged human HOP protein (SPR-302).
product information
Catalog No :
SPR-302
Product Name :
HOP Protein
Description :
Human Recombinant HOP Protein
Size :
50 µg
Research Area(s) :
Cancer Heat Shock
Alternative Name(s) :
HSP co chaperone Protein
Category :
Protein
Nature :
Recombinant
Accession Number :
NP_006810.1
Swiss-Prot :
P31948
Applications :
WB SDS-PAGE Functional Assay
Species :
Human
Expression System :
E. coli
Amino Acid Sequence :
MGHHHHHHMEQVNELKEKGNKALSVGNIDDALQCYSEAI
KLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPD
WGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLK
EGLQNMEARLAERKFMNPFNMPNLYQKLESDPRTRTLLS
DPTYRELIEQLRNKPSDLGTKLQDPRIMTTLSVLLGVDL
GSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQAL
KEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQ
AAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIAKAYA
RIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAE
KILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKH
YTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEECI
QLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDLDSS
CKEAADGYQRCMMAQYNRHDSPEDVKRRAMADPEVQQIM
SDPAMRLILEQMQKDPQALSEHLKNPVIAQKIQKLMDVG
LIAIR
Purity :
>90%
Protein Size :
~63 kDa
Conjugate :
His tag
Cellular Localization :
Cytoplasm Nucleus
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.