product summary
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company name :
StressMarq Biosciences
product type :
protein
product name :
GRP78 (Bip) Protein
catalog :
SPR-119B
quantity :
100 µg
price :
300 USD
citations: 7
Reference
Tanie Y, Kuboyama T, Tohda C. GRP78-Mediated Signaling Contributes to Axonal Growth Resulting in Motor Function Recovery in Spinal Cord-Injured Mice. Front Pharmacol. 2020;11:789 pubmed publisher
Aksoy M, Kim V, Cornwell W, Rogers T, Kosmider B, Bahmed K, et al. Secretion of the endoplasmic reticulum stress protein, GRP78, into the BALF is increased in cigarette smokers. Respir Res. 2017;18:78 pubmed publisher
Kosakowska Cholody T, Lin J, Srideshikan S, Scheffer L, Tarasova N, Acharya J. HKH40A downregulates GRP78/BiP expression in cancer cells. Cell Death Dis. 2014;5:e1240 pubmed publisher
Ding Y, Li J, Wu Q, Yang P, Luo B, Xie S, et al. IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cells. J Immunol. 2013;191:1614-24 pubmed publisher
Bruchmann A, Roller C, Walther T, Schafer G, Lehmusvaara S, Visakorpi T, et al. Bcl-2 associated athanogene 5 (Bag5) is overexpressed in prostate cancer and inhibits ER-stress induced apoptosis. BMC Cancer. 2013;13:96 pubmed publisher
Maddalo D, Neeb A, Jehle K, Schmitz K, Muhle Goll C, Shatkina L, et al. A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death. PLoS ONE. 2012;7:e45690 pubmed publisher
Dieudé M, Correa J, Neville C, Pineau C, Levine J, Subang R, et al. Association of autoantibodies to heat-shock protein 60 with arterial vascular events in patients with antiphospholipid antibodies. Arthritis Rheum. 2011;63:2416-24 pubmed publisher
image
image 1 :
StressMarq Biosciences SPR-119B image 1
SDS-PAGE of 78kDa native human Grp78 protein (SPR-119).
product information
Catalog No :
SPR-119B
Product Name :
GRP78 (Bip) Protein
Product Type :
Protein
Nature :
Recombinant
Species :
Human
Conjugate :
No tag
Size :
100 µg
List Price USD :
300 USD
Description :
Human Recombinant GRP78 (Bip) Full Length Protein
Applications :
WB SDS-PAGE ATPase Activity Assay Functional Assay ELISA
Alternative Name(s) :
BIP Protein, Grp78 Protein, HSPA5 Protein, MIF2 Protein, immunoglobulin heavy chain binding Protein
Cellular Localization :
Endoplasmic Reticulum Lumen Melanosome
Purity :
>90%
Purification :
Affinity Purified
Accession Number :
NM_005347
Swiss-Prot :
P11021
Expression System :
E. coli
Protein Size :
~78 kDa
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.