product summary
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company name :
StressMarq Biosciences
product type :
protein
product name :
HSP70 Protein
catalog :
SPR-108
quantity :
50 µg
more info or order :
StressMarq Biosciences product webpage
citations: 6
Reference
Alhamoud I, Legan S, Gattineni J, Baum M. Sex differences in prenatal programming of hypertension by dexamethasone. Exp Biol Med (Maywood). 2021;246:1554-1562 pubmed publisher
Fitter S, Gronthos S, Ooi S, Zannettino A. The Mesenchymal Precursor Cell Marker Antibody STRO-1 Binds to Cell Surface Heat Shock Cognate 70. Stem Cells. 2017;35:940-951 pubmed publisher
Fong J, Sreedhara K, Deng L, Varki N, Angata T, Liu Q, et al. Immunomodulatory activity of extracellular Hsp70 mediated via paired receptors Siglec-5 and Siglec-14. EMBO J. 2015;34:2775-88 pubmed publisher
Ciplys E, Aučynaitė A, Slibinskas R. Generation of human ER chaperone BiP in yeast Saccharomyces cerevisiae. Microb Cell Fact. 2014;13:22 pubmed publisher
Chen M, Zhang Y, Yu V, Chong Y, Yoshioka T, Ge R. Isthmin targets cell-surface GRP78 and triggers apoptosis via induction of mitochondrial dysfunction. Cell Death Differ. 2014;21:797-810 pubmed publisher
Zwang N, Hoffert J, Pisitkun T, Moeller H, Fenton R, Knepper M. Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry. J Proteome Res. 2009;8:1540-54 pubmed publisher
image
image 1 :
StressMarq Biosciences SPR-108 image 1
SDS-PAGE of 70kDa Hsp70 protein (SPR-108).
product information
Catalog No :
SPR-108
Product Name :
HSP70 Protein
Description :
Active Human Recombinant HSP70 Full Length Protein
Size :
50 µg
Research Area(s) :
Cancer Heat Shock Cell Signaling Protein Trafficking Chaperone Proteins Cancer Tumor Biomarkers
Alternative Name(s) :
HSP70 1 Protein, HSP70 2 Protein, HSP70.1 Protein, HSP72 Protein, HSP73 Protein, HSPA1 Protein, HSPA1A Protein, HSPA1B Protein
Category :
Protein
Nature :
Recombinant
Accession Number :
NM_005345
Swiss-Prot :
P0DMV8/P0DMV9
Applications :
WB SDS-PAGE ATPase Activity Assay Functional Assay ELISA
Species :
Human
Expression System :
E. coli
Protein Length :
Full Length
Amino Acid Sequence :
MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTP
SYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKF
GDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPE
EISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQ
ATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNV
LIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFD
NRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRT
LSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRS
TLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQ
DFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQD
LLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFT
TYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAP
RGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDK
GRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYA
FNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANT
LAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGA
QGPKGGSGSGPTIEEVD
Purity :
>90%
Protein Size :
~70 kDa
Conjugate :
No tag
Cellular Localization :
Cytoplasm
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.