HSP90 alpha Protein | StressMarq Biosciences SPR-101 product information

product summary

company name :

StressMarq Biosciences

product type :

protein

product name :

HSP90 alpha Protein

catalog :

SPR-101

quantity :

50 µg

more info or order :

StressMarq Biosciences product webpage

citations: 15

Reference
Ding X, Qiu Y, Wu G, Li S, Cai M, Liang Y, et al. l-thyroxine attenuates extracellular Hsp90α-induced vascular endothelial calcification in diabetes mellitus, as revealed by parallel metabolic profiles. Atherosclerosis. 2024;392:117527 pubmed publisher
Wan X, Fang Y, Du J, Cai S, Dong H. GW4869 Can Inhibit Epithelial-Mesenchymal Transition and Extracellular HSP90α in Gefitinib-Sensitive NSCLC Cells. Onco Targets Ther. 2023;16:913-922 pubmed publisher
Zhang J, Liu L, Li Y, Huang Y, Xiao S, Deng Z, et al. HSP90 C-terminal domain inhibition promotes VDAC1 oligomerization via decreasing K274 mono-ubiquitination in Hepatocellular Carcinoma. Neoplasia. 2023;44:100935 pubmed publisher
Ding X, Meng C, Dong H, Zhang S, Zhou H, Tan W, et al. Extracellular Hsp90α, which participates in vascular inflammation, is a novel serum predictor of atherosclerosis in type 2 diabetes. BMJ Open Diabetes Res Care. 2022;10: pubmed publisher
Ye C, Huang C, Zou M, Hu Y, Luo L, Wei Y, et al. The role of secreted Hsp90α in HDM-induced asthmatic airway epithelial barrier dysfunction. BMC Pulm Med. 2019;19:218 pubmed publisher
Schiltz D, Wenzel C, Brix E, Prantl L, Taeger C. Salvage of both feet after complete resection of large carcinomas and local infection using a new negative pressure wound dressing in combination with intermittent instillation therapy. J Tissue Viability. 2019;28:120-123 pubmed publisher
Wang N, Chen S, Zhang B, Li S, Jin F, Gao D, et al. 8u, a pro-apoptosis/cell cycle arrest compound, suppresses invasion and metastasis through HSP90α downregulating and PI3K/Akt inactivation in hepatocellular carcinoma cells. Sci Rep. 2018;8:309 pubmed publisher
Dong H, Le Y, Wang Y, Zhao H, Huang C, Hu Y, et al. Extracellular heat shock protein 90? mediates HDM-induced bronchial epithelial barrier dysfunction by activating RhoA/MLC signaling. Respir Res. 2017;18:111 pubmed publisher
Goode K, Petrov D, Vickman R, Crist S, Pascuzzi P, Ratliff T, et al. Targeting the Hsp90 C-terminal domain to induce allosteric inhibition and selective client downregulation. Biochim Biophys Acta Gen Subj. 2017;1861:1992-2006 pubmed publisher
Saito Y, Akazawa Ogawa Y, Matsumura A, Saigoh K, Itoh S, Sutou K, et al. Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson's disease patients. Sci Rep. 2016;6:30793 pubmed publisher
Wang J, Grishin A, Ford H. Experimental Anti-Inflammatory Drug Semapimod Inhibits TLR Signaling by Targeting the TLR Chaperone gp96. J Immunol. 2016;196:5130-7 pubmed publisher
Bober J, Olsnes S, Kostas M, Bogacz M, Zakrzewska M, Otlewski J. Identification of new FGF1 binding partners-Implications for its intracellular function. IUBMB Life. 2016;68:242-51 pubmed publisher
Bartolini M, Wainer I, Bertucci C, Andrisano V. The rapid and direct determination of ATPase activity by ion exchange chromatography and the application to the activity of heat shock protein-90. J Pharm Biomed Anal. 2013;73:77-81 pubmed publisher
Rateb M, Houssen W, Arnold M, Abdelrahman M, Deng H, Harrison W, et al. Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp. J Nat Prod. 2011;74:1491-9 pubmed publisher
Gilbert K, Rowley B, Gomez Acevedo H, Blossom S. Coexposure to mercury increases immunotoxicity of trichloroethylene. Toxicol Sci. 2011;119:281-92 pubmed publisher

image

image 1 :

SDS-Page of human HSP90 Alpha protein (SPR-101). Lane 1: Molecular Weight Ladder (MW). Lane 2: Human HSP90 alpha protein (SPR-101).

product information

Catalog No :

SPR-101

Product Name :

HSP90 alpha Protein

Description :

Human Recombinant HSP90 alpha Protein

Size :

50 µg

Research Area(s) :

Cancer Heat Shock Cell Signaling Protein Trafficking Chaperone Proteins Cancer Tumor Biomarkers

Alternative Name(s) :

HSP86 Protein, HSP89A Protein, HSP90A Protein, HSP90AA1 Protein, HSPC1 Protein, HSPCA Protein, HSPCAL3 Protein, HSP90alpha Protein

Category :

Protein

Nature :

Recombinant

Accession Number :

NP_001017963.2

Swiss-Prot :

P07900

Applications :

WB SDS-PAGE ATPase Activity Assay Surface Plasmon Resonance (SPR) DARTs Assay (Drug Affinity Responsive Target Stability Assay) SB (Skin Blotting)

Species :

Human

Expression System :

E. coli

Protein Length :

Full Length

Purity :

>90%

Protein Size :

~90 kDa

Conjugate :

No tag

Cellular Localization :

Cytoplasm Melanosome

more info or order :

StressMarq Biosciences product webpage