product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
ULK2 Antibody
catalog :
SPC-641D
quantity :
100 µg
price :
301.00 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, immunocytochemistry
more info or order :
StressMarq Biosciences product webpage
image
image 1 :
StressMarq Biosciences SPC-641D image 1
Western blot analysis of Rat brain showing detection of 112.7 kDa ULK2 protein using Rabbit Anti-ULK2 Polyclonal Antibody (SPC-641). Lane 1: Molecular Weight Ladder (MW). Lane 2: Rat brain lysates. Load: 15 µg. Block: 5% Skim Milk in 1X TBST. Primary Antibody: Rabbit Anti-ULK2 Polyclonal Antibody (SPC-641) at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Rabbit HRP at 1:2000 for 60 min at RT. Color Development: ECL solution for 6 min in RT. Predicted/Observed Size: 112.7 kDa. Other Band(s): ~70 kDa.
product information
Catalog No :
SPC-641D
Product Name :
ULK2 Antibody
Description :
Rabbit Anti-Human ULK2 Polyclonal
Target :
ULK2
Conjugate :
Unconjugated
2021 List Price :
301.00 USD
Currency :
USD
Research Area(s) :
Cell Signaling Protein Phosphorylation Serine / Threonine Kinases
Alternative Name(s) :
Serine/threonine-protein kinase ULK2 Antibody, EC:2.7.11.1 Antibody, Unc 51 (C. elegans) like kinase 2 Antibody, ULK2_HUMAN Antibody, KIAA0623 Antibody, ATG1B Antibody, Serine/threonine protein kinase ULK2 Antibody, Unc-51-like kinase 2 Antibody, Unc 51 like autophagy activating kinase 2 Antibody, Unc51.2 Antibody, ULK2 Antibody, Unc 51 like kinase 2 Antibody
Size :
100 µg
Category :
Antibodies
Product Type :
Polyclonal
Immunogen :
Synthetic peptide from the mid-protein of Human ULK2 (aa. 558-569)
Immunogen Species :
Human
Accession Number :
NP_001136082.1
Swiss-Prot :
Q8IYT8
Applications :
WB ICC/IF
Host Species :
Rabbit
Species Reactivity Abbreviation :
Hu Rt
Species Reactivity Full Name :
Human Rat
Antibody Dilution :
WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Peptide Affinity Purified
Storage Buffer :
PBS, 50% glycerol, 0.09% sodium azide
Concentration :
1 mg/ml
Specificity :
Detects ~100 kDa.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SPC-641D, RRID: AB_2705285
Certificate of Analysis :
A 1:1000 dilution of SPC-641 was sufficient for detection of ULK2 in 15 µg of Human HeLa Cell Lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cellular Localization :
Cytoplasmic Vesicle Membrane Peripheral Membrane Protein
Scientific Background :
UNC-51 like kinase 2 (ULK2) is widely expresed and contains an amino-terminal kinase domain followed by a central proline-serine rich domain and a highly conserved carboxy-terminal domain. It has been linked to axon growth and is essential for autophagy. Structurally, ULK2 is similar to ATG1.
References :
1. Okazaki N., et al. (2000) Brain Res Mol Brain Res. 85: 1-12. 2. Young A.R., et al. (2006) J Cell Sci. 119: 3888-900. 3. Kamada Y., et al. (2000) J Cell Biol. 150: 1507-13. 4. Lee S.B, et al. (2007) EMBO Rep. 8: 360-5. 5. Hara T., et al. (2008) J Cell Biol. 181: 497-510.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SPC-641_ULK2_Antibody_ICC-IF_Human_SK-N-BE-Cells-Human-Neuroblastoma-cells_60X_Composite_1.png SPC-641_ULK2_Antibody_WB_Rat_brain_1.png
Image Alternative Text :
Rabbit Anti-ULK2 Antibody used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human Neuroblastoma cell line (SK-N-BE) (SPC-641) Rabbit Anti-ULK2 Antibody used in Western blot (WB) on brain (SPC-641)
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.