product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
Amyloid Oligomers (A11) Antibody
catalog :
SPC-506
quantity :
100 µl
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
StressMarq Biosciences product webpage
citations: 7
Reference
Iwahashi N, Ikezaki M, Komohara Y, Fujiwara Y, Noguchi T, Nishioka K, et al. Cytoplasmic p53 aggregates accumulated in p53-mutated cancer correlate with poor prognosis. PNAS Nexus. 2022;1:pgac128 pubmed publisher
Xie Y, Naseri N, Fels J, Kharel P, Na Y, Lane D, et al. Lysosomal exocytosis releases pathogenic α-synuclein species from neurons in synucleinopathy models. Nat Commun. 2022;13:4918 pubmed publisher
Hamaguchi T, Kim J, Hasegawa A, Goto R, Sakai K, Ono K, et al. Exogenous Aβ seeds induce Aβ depositions in the blood vessels rather than the brain parenchyma, independently of Aβ strain-specific information. Acta Neuropathol Commun. 2021;9:151 pubmed publisher
Balczon R, Lin M, Lee J, Abbasi A, Renema P, Voth S, et al. Pneumonia initiates a tauopathy. FASEB J. 2021;35:e21807 pubmed publisher
Raber J, Perez R, Torres E, Krenik D, Boutros S, Patel E, et al. Effects of Chronic Secondhand Smoke (SHS) Exposure on Cognitive Performance and Metabolic Pathways in the Hippocampus of Wild-Type and Human Tau Mice. Environ Health Perspect. 2021;129:57009 pubmed publisher
Balczon R, Morrow K, Leavesley S, Francis C, Stevens T, Agwaramgbo E, et al. Cystatin C regulates the cytotoxicity of infection-induced endothelial-derived β-amyloid. FEBS Open Bio. 2020;10:2464-2477 pubmed publisher
Voth S, Gwin M, FRANCIS C, Balczon R, Frank D, Pittet J, et al. Virulent Pseudomonas aeruginosa infection converts antimicrobial amyloids into cytotoxic prions. FASEB J. 2020;34:9156-9179 pubmed publisher
image
image 1 :
StressMarq Biosciences SPC-506 image 1
Dot blot analysis using Rabbit Anti-Amyloid Oligomers (A11) Polyclonal Antibody (SPC-506). Tissue: Abeta42 fibrils and prefibrillar oligomers. Species: Human. Primary Antibody: Rabbit Anti-Amyloid Oligomers (A11) Polyclonal Antibody (SPC-506) at 1:1000. Courtesy of: Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., et al. (2003). Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis. Science 300, 486–489. doi: 10.1126/science.1079469.
product information
Catalog No :
SPC-506
Product Name :
Amyloid Oligomers (A11) Antibody
Description :
Rabbit Anti-Human Amyloid Oligomers (A11) Polyclonal
Target :
Amyloid Oligomers (A11)
Conjugate :
Unconjugated
Size 1 :
100 µl
PMIDs :
36741442 35995799 34507620 34384141 34009016 33030263 32413239 25862419
Research Area(s) :
Neuroscience Cell Signaling Cardiovascular System Blood Neurodegeneration Alzheimer's Disease Amyloid
Alternative Name(s) :
Amyloid Oligomer alpha beta Antibody, A11 Antibody, Amyloid Oligomer AlphaBeta Antibody, APP Antibody
Category :
Antibodies
Product Type :
Polyclonal
Immunogen :
Synthetic molecular mimic of soluble human amyloid beta oligomers
Immunogen Species :
Human
Accession Number :
NM_000484.2
Swiss-Prot :
P05067
Applications :
WB IHC ICC/IF IP ELISA
Host Species :
Rabbit
Species Reactivity :
Human Mouse Rat Eukaryote
Specificity :
Recognizes all types of amyloid oligomers. Appears to recognize a peptide backbone epitope that is common to amyloid oligomers, but is not found in native proteins, amyloidogenic monomer or mature amyloid fibrils.
Image Filenames :
SPC-506-Amyloid-Oligomers-A11-Antibody-IHC-Human-Alzheimer's-Disease-brain-1.png SPC-506_Amyloid_Antibody_WB_Human_AB42-fibrils-and-prefibrillar-oligomers_1.png SPC-506_Amyloid_Antibody_DB_Human_AB42-fibrils-and-prefibrillar-oligomers_1.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.