product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
Aquaporin 3 Antibody
catalog :
SPC-504D
quantity :
100 µg
price :
300.00 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
StressMarq Biosciences product webpage
citations: 1
Reference
Sun Y, Zhang Y, Zhu Y, Zhang A, Huang S, Yin X, et al. Inhibition of mitochondrial complex-1 restores the downregulation of aquaporins in obstructive nephropathy. Am J Physiol Renal Physiol. 2016;311:F777-F786 pubmed publisher
image
image 1 :
StressMarq Biosciences SPC-504D image 1
Western blot analysis of Rat kidney inner medullary homogenates showing detection of Aquaporin 3 protein using Rabbit Anti-Aquaporin 3 Polyclonal Antibody (SPC-504). Primary Antibody: Rabbit Anti-Aquaporin 3 Polyclonal Antibody (SPC-504) at 1:2000.
product information
Catalog No :
SPC-504D
Product Name :
Aquaporin 3 Antibody
Description :
Rabbit Anti-Rat Aquaporin 3 Polyclonal
Target :
Aquaporin 3
Conjugate :
Unconjugated
2021 List Price :
300.00 USD
Currency :
USD
Research Area(s) :
Neuroscience Neurotransmission Ion Channels Aquaporins
Alternative Name(s) :
AQP3 Antibody, AQP 3 Antibody, AQP-3 Antibody, Aqp3 Antibody, AQP3_HUMAN Antibody, Aquaglyceroporin-3 Antibody, Aquaporin 3 (GIL blood group) Antibody, Aquaporin 3 (Gill blood group) Antibody, Aquaporin-3 Antibody, Aquaporin3 Antibody, GIL Antibody, Gill blood group Antibody
Size :
100 µg
Category :
Antibodies
Product Type :
Polyclonal
Immunogen :
Produced against the C-terminal peptide (Sequence N-CHLEQPPPSTEAENVKLAHMKHKEQI) of rat aquaporin 3
Immunogen Species :
Rat
Accession Number :
NP_113891.1
Swiss-Prot :
P47862
Applications :
WB IHC ICC/IF
Host Species :
Rabbit
Species Reactivity Abbreviation :
Hu Ms Rt
Species Reactivity Full Name :
Human Mouse Rat
Antibody Dilution :
WB (1:2000), IHC (1:200), ICC/IF (1:400); optimal dilutions for assays should be determined by the user.
Purification :
Protein A Purified
Storage Buffer :
PBS, 50% glycerol, 0.09% sodium azide
Concentration :
1 mg/ml
Specificity :
Detects ~31.5kDa. May detect larger glycosylated bands ~35-50kDa.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SPC-504D, RRID: AB_10963586
Certificate of Analysis :
0.5 µg/ml of SPC-504 was sufficient for detection of aquaporin 3 in 10 µg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
Cellular Localization :
Membrane
Scientific Background :
Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquaporin 3 is found in the basolateral cell membrane of principal collecting duct cells and provide a pathway for water to exit these cells (3). AQP3 gene expression is not regulated by vasopressin (4).
References :
1. Gonen T., Walz T. (2006) Q. Rev. Biophys. 39(4): 361-396. 2. Knepper M.A. (1994) Proc Natl. Acad Sci. USA. 91(14): 6255-6258. 3. Sasaki S., Ishibashi K., and Marumo F. (1998) Annu Rev Physiol. 60: 199-220. 4. Dibas A.I., Mia A.J., Yorio T. (1998) Proc Soc Exp Med. 219(3): 183-199.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SPC-504_Aquaporin-3_Antibody_IHC_Rat_kidney-tissue_1.png SPC-504_Aquaporin-3_Antibody_WB_Rat_kidney-tissue-lysates_1.png
Image Alternative Text :
Rabbit Anti-Aquaporin 3 Antibody used in Immunohistochemistry (IHC) on Rat kidney tissue (SPC-504) Rabbit Anti-Aquaporin 3 Antibody used in Western blot (WB) on Rat kidney inner medullary homogenates (SPC-504)
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.