Aquaporin 1 Antibody | StressMarq Biosciences SPC-502D product information

product summary

company name :

StressMarq Biosciences

product type :

antibody

product name :

Aquaporin 1 Antibody

catalog :

SPC-502D

quantity :

100 µg

price :

300.00 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

StressMarq Biosciences product webpage

citations: 2

Reference
Sun Y, Zhang Y, Zhu Y, Zhang A, Huang S, Yin X, et al. Inhibition of mitochondrial complex-1 restores the downregulation of aquaporins in obstructive nephropathy. Am J Physiol Renal Physiol. 2016;311:F777-F786 pubmed publisher
Erikci A, Ucar G, Yabanoglu Ciftci S. Role of serotonin in the regulation of renal proximal tubular epithelial cells. Ren Fail. 2016;38:1141-50 pubmed publisher

image

image 1 :

Western blot analysis of Rat kidney inner medullary homogenates showing detection of Aquaporin 1 protein using Rabbit Anti-Aquaporin 1 Polyclonal Antibody (SPC-502). Primary Antibody: Rabbit Anti-Aquaporin 1 Polyclonal Antibody (SPC-502) at 1:2000. Showing glycosylated and non-glycosylated bands.

product information

Catalog No :

SPC-502D

Product Name :

Aquaporin 1 Antibody

Description :

Rabbit Anti-Rat Aquaporin 1 Polyclonal

Target :

Aquaporin 1

Conjugate :

Unconjugated

2021 List Price :

300.00 USD

Currency :

USD

Research Area(s) :

Neuroscience Neurotransmission Ion Channels Aquaporins

Alternative Name(s) :

AQP1 Antibody, AQP 1 Antibody, AQP CHIP Antibody, AQP-1 Antibody, AQP1 Antibody, AQP1_HUMAN Antibody, Aquaporin CHIP Antibody, Aquaporin-1 Antibody, Aquaporin-CHIP Antibody, Aquaporin1 Antibody, Channel forming integral protein 28kDa Antibody, Channel like integral membrane protein 28 kDa Antibody, CHIP 28 Antibody, CHIP28 Antibody, CO Antibody, Colton blood group Antibody, Growth factor induced delayed early response protein Antibody, MGC26324 Antibody, Urine water channel Antibody, Water channel protein CHIP 29 Antibody, Water channel protein CHIP29 Antibody, Water channel protein for red blood cells and kidney proximal tubule Antibody

Size :

100 µg

Category :

Antibodies

Product Type :

Polyclonal

Immunogen :

Produced against the N-terminal peptide (sequence N-MASEFKKKLF) of rat Aquaporin 1

Immunogen Species :

Rat

Accession Number :

NP_036910.1

Swiss-Prot :

P29975

Applications :

WB IHC ICC/IF

Host Species :

Rabbit

Species Reactivity Abbreviation :

Hu Ms Rt

Species Reactivity Full Name :

Human Mouse Rat

Antibody Dilution :

WB (1:2000), IHC (1:200), ICC/IF (1:400); optimal dilutions for assays should be determined by the user.

Purification :

Protein A Purified

Storage Buffer :

PBS, 50% glycerol, 0.09% sodium azide

Concentration :

1 mg/ml

Specificity :

Detects ~28.5kDa. May detect larger glycosylated bands ~35-50kDa.

Storage Temperature :

-20ºC

Shipping Temperature :

Blue Ice or 4ºC

Cite this Product :

StressMarq Biosciences Cat# SPC-502D, RRID: AB_10984185

Certificate of Analysis :

0.5 µg/ml of SPC-502 was sufficient for detection of aquaporin 1 in 10 µg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Cellular Localization :

Membrane

Scientific Background :

Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquarporin 1 is a widely expressed water channel, found in the basolateral and apical plasma membranes of the proximal tubes, the descending loop of Henel and in the descending portion of the vasa recta. Additionally it is found in red blood cells, vascular endothelium, gastrointestinal tract, sweat glands and lungs. It is not regulated by vasopressin (3).

References :

1. Gonen T., Walz T. (2006) Q. Rev. Biophys. 39(4): 361-396. 2. Knepper M.A. (1994) Proc Natl. Acad Sci. USA. 91(14): 6255-6258. 3. www.vivo.colostate.edu/hbooks/molecules/aquaporins.html

Field of Use :

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Image Filenames :

SPC-502_Aquaporin-1_Antibody_IHC_Rat_kidney-tissue_1.png SPC-502_Aquaporin-1_Antibody_WB_Rat_kidney-tissue-lysates_1.png

Image Alternative Text :

Rabbit Anti-Aquaporin 1 Antibody used in Immunohistochemistry (IHC) on Rat kidney tissue (SPC-502) Rabbit Anti-Aquaporin 1 Antibody used in Western blot (WB) on Rat kidney inner medullary homogenates (SPC-502)

more info or order :

StressMarq Biosciences product webpage