product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
ENaC beta Antibody
catalog :
SPC-404
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
StressMarq Biosciences product webpage
citations: 31
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 5b
Ferdaus M, Barber K, López Cayuqueo K, Terker A, Argaiz E, Gassaway B, et al. SPAK and OSR1 play essential roles in potassium homeostasis through actions on the distal convoluted tubule. J Physiol. 2016;594:4945-66 pubmed publisher
  • western blot; mouse; fig 1
Patel Chamberlin M, Varasteh Kia M, Xu J, Barone S, Zahedi K, Soleimani M. The Role of Epithelial Sodium Channel ENaC and the Apical Cl-/HCO3- Exchanger Pendrin in Compensatory Salt Reabsorption in the Setting of Na-Cl Cotransporter (NCC) Inactivation. PLoS ONE. 2016;11:e0150918 pubmed publisher
Vitzthum H, Koch M, Eckermann L, Svendsen S, Berg P, H xfc bner C, et al. The AE4 transporter mediates kidney acid-base sensing. Nat Commun. 2023;14:3051 pubmed publisher
Xu P, Sudarikova A, Ilatovskaya D, Gildea J, Akhter M, Carey R, et al. Epithelial Sodium Channel Alpha Subunit (αENaC) Is Associated with Inverse Salt Sensitivity of Blood Pressure. Biomedicines. 2022;10: pubmed publisher
Hu C, Lakshmipathi J, Stuart D, Kohan D. Profiling renal sodium transporters in mice with nephron Ift88 disruption: Association with sex, cysts, and blood pressure. Physiol Rep. 2022;10:e15206 pubmed publisher
Shi S, Buck T, Nickerson A, Brodsky J, Kleyman T. Paraoxonase 2 is an ER chaperone that regulates the epithelial Na+ channel. Am J Physiol Cell Physiol. 2022;322:C111-C121 pubmed publisher
Xiao Y, Duan X, Zhang D, Wang W, Lin D. Deletion of renal Nedd4-2 abolishes the effect of high K+ intake on Kir4.1/Kir5.1 and NCC activity in the distal convoluted tubule. Am J Physiol Renal Physiol. 2021;321:F1-F11 pubmed publisher
Duan X, Wu P, Zhang D, Gao Z, Xiao Y, Ray E, et al. Deletion of Kir5.1 abolishes the effect of high Na+ intake on Kir4.1 and Na+-Cl- cotransporter. Am J Physiol Renal Physiol. 2021;320:F1045-F1058 pubmed publisher
Grant G, Coca C, Zhao X, Helms M. Oxidized Glutathione Increases Delta-Subunit Expressing Epithelial Sodium Channel Activity in Xenopus laevis Oocytes. Emed Res. 2020;2: pubmed
Song C, Yue Q, Moseley A, Al Khalili O, Wynne B, Ma H, et al. Myristoylated alanine-rich C kinase substrate-like protein-1 regulates epithelial sodium channel activity in renal distal convoluted tubule cells. Am J Physiol Cell Physiol. 2020;319:C589-C604 pubmed publisher
Rein J, Heja S, Flores D, Carrisoza Gaytán R, Lin N, Homan K, et al. Effect of luminal flow on doming of mpkCCD cells in a 3D perfusable kidney cortical collecting duct model. Am J Physiol Cell Physiol. 2020;319:C136-C147 pubmed publisher
Wu P, Gao Z, Zhang D, Duan X, Terker A, Lin D, et al. Effect of Angiotensin II on ENaC in the Distal Convoluted Tubule and in the Cortical Collecting Duct of Mineralocorticoid Receptor Deficient Mice. J Am Heart Assoc. 2020;9:e014996 pubmed publisher
Wang M, Guo X, Zhao H, Lv J, Wang H, An Y. Adenosine A2B receptor activation stimulates alveolar fluid clearance through alveolar epithelial sodium channel via cAMP pathway in endotoxin-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2020;318:L787-L800 pubmed publisher
Lee H, Harris A, Romero M, Welling P, Wingo C, Verlander J, et al. NBCe1-A is required for the renal ammonia and K+ response to hypokalemia. Am J Physiol Renal Physiol. 2020;318:F402-F421 pubmed publisher
Wang F, Luo R, Peng K, Liu X, Xu C, Lu X, et al. Soluble (pro)renin receptor regulation of ENaC involved in aldosterone signaling in cultured collecting duct cells. Am J Physiol Renal Physiol. 2020;318:F817-F825 pubmed publisher
Lu X, Rudemiller N, Wen Y, Ren J, Hammer G, Griffiths R, et al. A20 in Myeloid Cells Protects Against Hypertension by Inhibiting Dendritic Cell-Mediated T-Cell Activation. Circ Res. 2019;125:1055-1066 pubmed publisher
Wu M, Liang C, Yu X, Song B, Yue Q, Zhai Y, et al. Lovastatin attenuates hypertension induced by renal tubule-specific knockout of ATP-binding cassette transporter A1, by inhibiting epithelial sodium channels. Br J Pharmacol. 2019;176:3695-3711 pubmed publisher
Khedr S, Palygin O, Pavlov T, Blass G, Levchenko V, Alsheikh A, et al. Increased ENaC activity during kidney preservation in Wisconsin solution. BMC Nephrol. 2019;20:145 pubmed publisher
Blass G, Klemens C, Brands M, Palygin O, Staruschenko A. Postprandial Effects on ENaC-Mediated Sodium Absorption. Sci Rep. 2019;9:4296 pubmed publisher
Chen J, Lo Y, Lin Y, Lin S, Huang C, Cheng C. WNK4 kinase is a physiological intracellular chloride sensor. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
Ilatovskaya D, Levchenko V, Pavlov T, Isaeva E, Klemens C, Johnson J, et al. Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC). EBioMedicine. 2019;40:663-674 pubmed publisher
Wu P, Gao Z, Su X, Wang M, Wang W, Lin D. Kir4.1/Kir5.1 Activity Is Essential for Dietary Sodium Intake-Induced Modulation of Na-Cl Cotransporter. J Am Soc Nephrol. 2019;30:216-227 pubmed publisher
Romero C, Kumar N, Nakagawa P, Worou M, Liao T, Peterson E, et al. Renal release of N-acetyl-seryl-aspartyl-lysyl-proline is part of an antifibrotic peptidergic system in the kidney. Am J Physiol Renal Physiol. 2019;316:F195-F203 pubmed publisher
Fu Z, Hu J, Zhou L, Chen Y, Deng M, Liu X, et al. (Pro)renin receptor contributes to pregnancy-induced sodium-water retention in rats via activation of intrarenal RAAS and α-ENaC. Am J Physiol Renal Physiol. 2019;316:F530-F538 pubmed publisher
Gao Y, Stuart D, Takahishi T, Kohan D. Nephron-Specific Disruption of Nitric Oxide Synthase 3 Causes Hypertension and Impaired Salt Excretion. J Am Heart Assoc. 2018;7: pubmed publisher
Ramkumar N, Stuart D, Mironova E, Abraham N, Gao Y, Wang S, et al. Collecting duct principal, but not intercalated, cell prorenin receptor regulates renal sodium and water excretion. Am J Physiol Renal Physiol. 2018;315:F607-F617 pubmed publisher
You H, Ge Y, Zhang J, Cao Y, Xing J, Su D, et al. Derlin-1 promotes ubiquitylation and degradation of the epithelial Na+ channel, ENaC. J Cell Sci. 2017;130:1027-1036 pubmed publisher
Klemens C, Edinger R, Kightlinger L, Liu X, Butterworth M. Ankyrin G Expression Regulates Apical Delivery of the Epithelial Sodium Channel (ENaC). J Biol Chem. 2017;292:375-385 pubmed publisher
Pavlov T, Levchenko V, Ilatovskaya D, Moreno C, Staruschenko A. Renal sodium transport in renin-deficient Dahl salt-sensitive rats. J Renin Angiotensin Aldosterone Syst. 2016;17: pubmed publisher
Xu C, Lu A, Wang H, Fang H, Zhou L, Sun P, et al. (Pro)Renin receptor regulates potassium homeostasis through a local mechanism. Am J Physiol Renal Physiol. 2017;313:F641-F656 pubmed publisher
Ramkumar N, Stuart D, Mironova E, Bugay V, Wang S, Abraham N, et al. Renal tubular epithelial cell prorenin receptor regulates blood pressure and sodium transport. Am J Physiol Renal Physiol. 2016;311:F186-94 pubmed publisher
product information
Catalog No :
SPC-404
Product Name :
ENaC beta Antibody
Description :
Rabbit Anti-Rat ENaC beta Polyclonal
Target :
ENaC
Conjugate :
Unconjugated
Size 1 :
100 µg
PMIDs :
37236964 34852210 35625718 35274831 34029145 33900854 30559144 32639874 32656545 32401606 32208832 32129084 3212908431841392 31841393 31630621 31222723 31222723 31035971 30862903 30745171 30765526 30745171 30403163 30379098 29997131 29790390 28137758 28137758 27895120 27443990 27440776 27068441 27053687 26963391 26418861 26207612 25225551 24707975 25164814 25122048 24808538 24808538 24396058 24429824 24145067 23558339 23264685 22814399 23029554 22847418 22549242 21536685 21536685
Research Area(s) :
Neuroscience Neurotransmission Ion Channels Sodium Channels Epithelial Sodium Channels (ENaC)
Alternative Name(s) :
SCNN1B Antibody, Amiloride sensitive sodium channel subunit beta Antibody, Amiloride-sensitive sodium channel beta-subunit Antibody, Beta ENaC Antibody, Beta NaCH Antibody, ENaC beta Antibody, ENaCB Antibody, Epithelial Na(+) channel subunit beta Antibody, Epithelial Na+ channel beta subunit Antibody, Epithelial Na+ channel subunit beta Antibody, Epithelial sodium channel beta 2 subunit Antibody, Epithelial sodium channel beta 3 subunit Antibody, Nonvoltage gated sodium channel 1 beta subunit Antibody, Nonvoltage gated sodium channel 1 subunit beta Antibody, Nonvoltage-gated sodium channel 1 beta subunit Antibody, SCNEB Antibody, SCNN 1B Antibody, Sodium channel nonvoltage gated 1 beta (Liddle syndrome) Antibody, Sodium channel nonvoltage gated 1 beta Antibody
Category :
Antibodies
Product Type :
Polyclonal
Immunogen :
Produced against the C-terminal tail (amino acids 617-638) of rat beta ENaC (antibody designation 3755-2)
Immunogen Species :
Rat
Accession Number :
NP_036780
Swiss-Prot :
P37090
Applications :
WB IHC ICC/IF IP
Host Species :
Rabbit
Species Reactivity :
Human Mouse Rat Xenopus Hamster
Specificity :
Detects ~87kDa.
Image Filenames :
SPC-404_ENaC_Antibody_IHC_Rat_kidney-tissue_1.png SPC-404_ENaC_Antibody_WB_Rat_kidney-tissue-lysates_1.png SPC-404_ENaC_Antibody_WB_Mouse_mpkCCD-cell-lysates_1.png SPC-404_ENaC_Antibody_WB_Mouse_kidney-cortex_1.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.