product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
NCC Antibody
catalog :
SPC-402
quantity :
100 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
StressMarq Biosciences product webpage
citations: 23
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 1
Patel Chamberlin M, Varasteh Kia M, Xu J, Barone S, Zahedi K, Soleimani M. The Role of Epithelial Sodium Channel ENaC and the Apical Cl-/HCO3- Exchanger Pendrin in Compensatory Salt Reabsorption in the Setting of Na-Cl Cotransporter (NCC) Inactivation. PLoS ONE. 2016;11:e0150918 pubmed publisher
Han X, Sun Z. Adult Mouse Kidney Stem Cells Orchestrate the De Novo Assembly of a Nephron via Sirt2-Modulated Canonical Wnt/β-Catenin Signaling. Adv Sci (Weinh). 2022;9:e2104034 pubmed publisher
Gholam M, Ko B, Ghazi Z, Hoover R, Alli A. The Pharmacological Inhibition of CaMKII Regulates Sodium Chloride Cotransporter Activity in mDCT15 Cells. Biology (Basel). 2021;10: pubmed publisher
Kortenoeven M, Esteva Font C, Dimke H, Poulsen S, Murali S, Fenton R. High dietary potassium causes ubiquitin-dependent degradation of the kidney sodium-chloride cotransporter. J Biol Chem. 2021;297:100915 pubmed publisher
Alhamoud I, Legan S, Gattineni J, Baum M. Sex differences in prenatal programming of hypertension by dexamethasone. Exp Biol Med (Maywood). 2021;246:1554-1562 pubmed publisher
Son S, Hwang S, Park J, Ko Y, Yun S, Lee J, et al. In vivo silencing of amphiregulin by a novel effective Self-Assembled-Micelle inhibitory RNA ameliorates renal fibrosis via inhibition of EGFR signals. Sci Rep. 2021;11:2191 pubmed publisher
Xue J, Thomas L, Dominguez Rieg J, Fenton R, Rieg T. Genetic deletion of connexin 37 causes polyuria and polydipsia. PLoS ONE. 2020;15:e0244251 pubmed publisher
Walter C, Rafael C, Lasaad S, Baron S, Salhi A, Crambert G. H,K-ATPase type 2 regulates gestational extracellular compartment expansion and blood pressure in mice. Am J Physiol Regul Integr Comp Physiol. 2020;318:R320-R328 pubmed publisher
Ferrè S, Deng Y, Huen S, Lu C, Scherer P, Igarashi P, et al. Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation. Kidney Int. 2019;96:1359-1373 pubmed publisher
Dvela Levitt M, Kost Alimova M, Emani M, Kohnert E, Thompson R, Sidhom E, et al. Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy. Cell. 2019;178:521-535.e23 pubmed publisher
Wang J, Wang C, Xu N, Liu Z, Pang D, Zhang Z. A virus-induced kidney disease model based on organ-on-a-chip: Pathogenesis exploration of virus-related renal dysfunctions. Biomaterials. 2019;219:119367 pubmed publisher
Dalghi M, Clayton D, Ruiz W, Al Bataineh M, Satlin L, Kleyman T, et al. Expression and distribution of PIEZO1 in the mouse urinary tract. Am J Physiol Renal Physiol. 2019;317:F303-F321 pubmed publisher
Bissler J, Zadjali F, Bridges D, Astrinidis A, Barone S, Yao Y, et al. Tuberous sclerosis complex exhibits a new renal cystogenic mechanism. Physiol Rep. 2019;7:e13983 pubmed publisher
Xu J, Barone S, Zahedi K, Brooks M, Soleimani M. Slc4a8 in the Kidney: Expression, Subcellular Localization and Role in Salt Reabsorption. Cell Physiol Biochem. 2018;50:1361-1375 pubmed publisher
Cosgrove D, Dufek B, Meehan D, Delimont D, Hartnett M, Samuelson G, et al. Lysyl oxidase like-2 contributes to renal fibrosis in Col4α3/Alport mice. Kidney Int. 2018;94:303-314 pubmed publisher
Salih M, Bovée D, van der Lubbe N, Danser A, Zietse R, Feelders R, et al. Increased Urinary Extracellular Vesicle Sodium Transporters in Cushing Syndrome With Hypertension. J Clin Endocrinol Metab. 2018;103:2583-2591 pubmed publisher
Poulsen S, Limbutara K, Fenton R, Pisitkun T, Christensen B. RNA sequencing of kidney distal tubule cells reveals multiple mediators of chronic aldosterone action. Physiol Genomics. 2018;50:343-354 pubmed publisher
Liu M, Zhu Y, Sun Y, Wen Z, Huang S, Ding G, et al. MnTBAP therapy attenuates the downregulation of sodium transporters in obstructive kidney disease. Oncotarget. 2018;9:394-403 pubmed publisher
Poulsen S, Kristensen T, Brooks H, Kohan D, Rieg T, Fenton R. Role of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus. JCI Insight. 2017;2:e91042 pubmed publisher
Poulsen S, Christensen B. Long-term aldosterone administration increases renal Na+-Cl- cotransporter abundance in late distal convoluted tubule. Am J Physiol Renal Physiol. 2017;313:F756-F766 pubmed publisher
Xu C, Lu A, Wang H, Fang H, Zhou L, Sun P, et al. (Pro)Renin receptor regulates potassium homeostasis through a local mechanism. Am J Physiol Renal Physiol. 2017;313:F641-F656 pubmed publisher
Procino G, Carmosino M, Milano S, Dal Monte M, Schena G, Mastrodonato M, et al. β3 adrenergic receptor in the kidney may be a new player in sympathetic regulation of renal function. Kidney Int. 2016;90:555-67 pubmed publisher
Poulsen S, Praetorius J, Damkier H, Miller L, Nelson R, Hummler E, et al. Reducing αENaC expression in the kidney connecting tubule induces pseudohypoaldosteronism type 1 symptoms during K+ loading. Am J Physiol Renal Physiol. 2016;310:F300-10 pubmed publisher
product information
Catalog No :
SPC-402
Product Name :
NCC Antibody
Description :
Rabbit Anti-Rat NCC Polyclonal
Target :
NCC
Conjugate :
Unconjugated
Size 1 :
100 µg
PMIDs :
35315252 34943250 34174287 33794700 33500443 31913688 33332450 31601454 31348885 31344514 31344514 31166705 30675765 30355950 29759420 29726949 29521601 29416622 28405619 27733368 27733368 27440776 27206969 26582762 26582762 26239621 25941340 25492393 24668812 24668812 24942911 22966159 23482560 23482560
Research Area(s) :
Cancer Neuroscience Pumps/Transporters Ion Pumps/Transporters
Alternative Name(s) :
SLC12A3 Antibody, SCYL1 Antibody,CKb10 Antibody, MCP-4 Antibody, MGC17134 Antibody, NCC-1 Antibody, NCC1 Antibody, SCYA13 Antibody, CK-beta-10 Antibody, monocyte chemoattractant protein 4 Antibody, monocyte chemotactic protein 4 Antibody, new CC chemokine 1 Antibody, small inducible cytokine A13 Antibody, small inducible cytokine subfamily A (Cys-Cys) member 13 Antibody, chemokine (C-C) Antibody
Category :
Antibodies
Product Type :
Polyclonal
Immunogen :
Produced against a synthetic peptide mapping to a segment of rat NCC (amino acids 74-95), N-terminal
Immunogen Species :
Rat
Accession Number :
NP_062218, NP_000330
Swiss-Prot :
P55018, P55017
Applications :
WB IHC ICC/IF IEM
Host Species :
Rabbit
Species Reactivity :
Human Mouse Rat Dog
Specificity :
Detects ~160kDa.
Image Filenames :
SPC-402_NCC_Antibody_IHC_Rat_kidney-tissue_2.png SPC-402_NCC_Antibody_WB_Rat_tissue-lysates_1.png SPC-402_NCC_Antibody_IHC_Mouse_kidney-tissue_1.png SPC-402_NCC_Antibody_IHC_Mouse_kidney-tissue_2.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.