product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
p62 Antibody
catalog :
SPC-219D
quantity :
100 µl
price :
291.00 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
more info or order :
StressMarq Biosciences product webpage
product information
Catalog No :
SPC-219D
Product Name :
p62 Antibody
Description :
Rabbit Anti-Human p62 Polyclonal
Target :
p62
Conjugate :
Unconjugated
2021 List Price :
291.00 USD
Currency :
USD
Research Area(s) :
Cancer Autophagy Cell Signaling Epigenetics and Nuclear Signaling Nuclear Signaling Pathways NFkB Pathway Cell Signaling Protein Trafficking Vesicle Transport Cell Signaling Epigenetics and Nuclear Signaling Transcription Polymerase Associated Factors Pol II Transcription Cardiovascular System Heart
Alternative Name(s) :
SQSTM1 Antibody, EBIAP Antibody, p60 Antibody, Sequestosome-1 Antibody, Phosphotyrosine independent ligand for the Lck SH2 domain p62 antibody, Ubiquitin binding protein p62 antibody
Size :
100 µl
Category :
Antibodies
Product Type :
Polyclonal
Immunogen :
Peptide derived from human p62 protein UBA domain (a.a 387-436)
Immunogen Species :
Human
Accession Number :
NP_714941.1
Swiss-Prot :
Q13501
Applications :
WB
Host Species :
Rabbit
Species Reactivity Abbreviation :
Hu
Species Reactivity Full Name :
Human
Antibody Dilution :
WB (1:5000); optimal dilutions for assays should be determined by the user.
Purification :
Salt precipitated
Storage Buffer :
PBS, 0.1% sodium azide
Specificity :
Ubiquitin binding autophagy receptor protein.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SPC-219D, RRID: AB_2704451
Certificate of Analysis :
A 1:500 dilution of SPC-219 was sufficient for detection of p62 in human spleen tissue lysate by electrochemiluminescence analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cellular Localization :
Cytoplasm Cytoplasmic Vesicle Autophagosome Endosome Late Endosome Nucleus Endoplasmic Reticulum
Scientific Background :
p62 is a scaffolding adaptor protein which is expressed under conditions of cellular stress. This protein has a variety of protein binding domains, allowing it to regulate a variety of signal transduction pathways. It also has an influence on protein trafficking, aggregation and degradation. p62 plays an important role in mediating autophagy.
References :
1. Wang L., Cano M., & Handa J. (2014) Biochim Biophys Acta. 1843(7): 1248-58.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.