product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
STI1P (HOP) Antibody
catalog :
SPC-203D
quantity :
100 µl
price :
278.00 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
Saccharomyces cerevisiae S288C, human, mouse
application :
western blot, ELISA, flow cytometry
more info or order :
StressMarq Biosciences product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 3
  • ELISA; human; 8 ng/ul; loading ...
Dias M, Martins V, Hajj G. Stress-Inducible Protein 1 (STI1): Extracellular Vesicle Analysis and Quantification. Methods Mol Biol. 2016;1459:161-74 pubmed publisher
Tsutsui K, Grabenhorst F, Kobayashi S, Schultz W. A dynamic code for economic object valuation in prefrontal cortex neurons. Nat Commun. 2016;7:12554 pubmed publisher
product information
Catalog No :
SPC-203D
Product Name :
STI1P (HOP) Antibody
Description :
Rabbit Anti-Yeast STI1P (HOP) Polyclonal
Target :
HOP
Conjugate :
Unconjugated
2021 List Price :
278.00 USD
Currency :
USD
Research Area(s) :
Cancer Heat Shock Cell Signaling Protein Trafficking Chaperone Proteins
Alternative Name(s) :
STIP1 Antibody, Sti1 yeast Antibody, Hop Antibody, HSC70/HSP90 organizing protein Antibody, Epididymis secretory sperm binding protein Li 94n antibody, HEL S 94n antibody, Hop antibody, HSC70/HSP90 organizing protein antibody, HSC70/HSP90-organizing protein antibody, IEF SSP 3521 antibody, NY REN 11 antigen antibody, P60 antibody, Renal carcinoma antigen NY-REN-11 antibody, STI1 antibody, STI1L antibody, STIP1 antibody, Stress induced phosphoprotein 1 antibody, Stress-induced-phosphoprotein 1 antibody, Transformation sensitive protein IEF SSP 3521 antibody, Transformation-sensitive protein IEF SSP 3521 antibody
Size :
100 µl
Category :
Antibodies
Product Type :
Polyclonal
Immunogen :
Yeast Sti1p raised against peptide(CDINQSNSMPKEPET)-KLH fusion
Immunogen Species :
Yeast
Accession Number :
NP_014670.1
Swiss-Prot :
P15705
Applications :
WB ELISA FCM
Host Species :
Rabbit
Species Reactivity Abbreviation :
Ms Ys
Species Reactivity Full Name :
Mouse Yeast
Antibody Dilution :
WB (1:2500); optimal dilutions for assays should be determined by the user.
Purification :
Rabbit Antiserum
Storage Buffer :
Rabbit Antiserum, PBS, 50% glycerol
Specificity :
Detects ~ 66kDa.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SPC-203D, RRID: AB_2704163
Certificate of Analysis :
0.5 µg/ml of SPC-203 was sufficient for detection of Sti1p (HOP) in 20 µg of W303 yeast lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
Cellular Localization :
Cytoplasm Nucleus
Scientific Background :
The stress inducible protein Sti1p is also commonly known as HSP70-HSP90 organization protein (HOP). It is located in diverse cellular regions and can move between the cytoplasm and the nucleus. It functions to reversibly link together the protein chaperones HSP70 and HSP90. HOP contains three tetratricopeptide repeat (TPR) domains, TPR1, TPR2a and TPR2b. HSP70 binding has been localized to TRP1 and sp90 binding have been localized to TPR2a (1). It has also been found to modulate the chaperone activities of the linked proteins and possible interacts with other chaperones and proteins. It has also been found to participate in other complexes besides the HSP70/HSP90 one (2). HOP is closely related to human 63kDa protein that is sensitive to simian virus SV40 transformation, and is related to the yeast heat-shock- responsive STI1 gene product (3, 4).
References :
1. Flom G., Behal R.H., Rosen L., Cole D.G., Johnson J.L. (2007) Biochem J. 404(1): 159-167. 2. Harst A., Lin H., Obermann W.M. (2005) Biochem J. 387 (pt3): 789-796. 3. Honore B.H., et al. (1992) J Biol Chem. 267: 8485- 8491. 4. Nicolet C.M., et al. (1989) Mol Cell Bio. 9: 3638-3646.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.