product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
4-Hydroxynonenal Antibody
catalog :
SMC-511
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
12F7
application :
western blot, ELISA, immunocytochemistry
more info or order :
StressMarq Biosciences product webpage
citations: 2
Reference
Guo B, Zheng C, Cao J, Luo F, Li H, Hu S, et al. Tetramethylpyrazine nitrone exerts neuroprotection via activation of PGC-1α/Nrf2 pathway in Parkinson's disease models. J Adv Res. 2023;: pubmed publisher
Herr S, Malek S, Rochat M, Moore G, Ko J, Shi R. Evidence of acrolein in synovial fluid of dogs with osteoarthritis as a potential inflammatory biomarker. BMC Musculoskelet Disord. 2021;22:894 pubmed publisher
image
image 1 :
StressMarq Biosciences SMC-511 image 1
Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-4-Hydroxynonenal Monoclonal Antibody, Clone 12F7 (SMC-511). Tissue: Embryonic kidney epithelial cell line (HEK293). Species: Human. Fixation: 5% Formaldehyde for 5 min. Primary Antibody: Mouse Anti-4-Hydroxynonenal Monoclonal Antibody (SMC-511) at 1:50 for 30-60 min at RT. Secondary Antibody: Goat Anti-Mouse Alexa Fluor 488 at 1:1500 for 30-60 min at RT. Counterstain: Phalloidin Alexa Fluor 633 F-Actin stain; DAPI (blue) nuclear stain at 1:250, 1:50000 for 30-60 min at RT. Magnification: 20X (2X Zoom). (A,C,E,G) - Untreated. (B,D,F,H) - Cells cultured overnight with 50 µM H2O2. (A,B) DAPI (blue) nuclear stain. (C,D) Phalloidin Alexa Fluor 633 F-Actin stain. (E,F) 4-Hydroxynonenal Antibody. (G,H) Composite. Courtesy of: Dr. Robert Burke, University of Victoria.
product information
Catalog No :
SMC-511
Product Name :
4-Hydroxynonenal Antibody
Description :
Mouse Anti-4-Hydroxynonenal (4-HNE) Monoclonal IgG1
Target :
4-Hydroxynonenal
Conjugate :
Unconjugated
Size :
100 µg
Research Area(s) :
Cancer Oxidative Stress Lipid peroxidation
Alternative Name(s) :
4-Hydroxynonenal Antibody, 4-Hydroxy Nonenal (4-HNE) Antibody, 4-Hydroxy Nonenal Antibody, 4-HNE Antibody, 4-hydroxy Hexenal Antibody, HNE Antibody, 4-hydroxy-2-nonenal Antibody
Product Type :
Monoclonal
Clone Number :
12F7
Immunogen :
Synthetic 4-Hydroxynonenal modified Keyhole Limpet Hemocyanin (KLH).
Applications :
WB ICC/IF ELISA
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity :
Species Independent
Purification :
Protein G Purified
Concentration :
1 mg/ml
Specificity :
Specific for 4-Hydroxynonenal (4-HNE) modified proteins. Does not detect free 4-Hydroxynonenal. Does not cross-react with 4-Hydroxy-2-hexenal, Acrolein, Crotonaldehyde, Hexanoyl Lysine, Malondialdehyde, or Methylglyoxal modified proteins.
Image Filenames :
SMC-511_4-Hydroxynonenal_Antibody_12F7_ICC-IF_Human_Embryonic-kidney-cells-HEK293_Composite_1.png SMC-511_4-hydroxy-nonenal_Antibody_12F7_WB_4-hydroxy-nonenal-BSA-Conjugate_1.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.