product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
Kv3.2 Antibody
catalog :
SMC-492D
quantity :
100 µg
price :
300.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S410-17
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
product information
Catalog No :
SMC-492D
Product Name :
Kv3.2 Antibody
Description :
Mouse Anti-Rat Kv3.2 Monoclonal IgG1
Target :
Kv3.2
Conjugate :
Unconjugated
2021 List Price :
300.00 USD
Currency :
USD
Research Area(s) :
Neuroscience Ion channels Potassium Channels Voltage-Gated Potassium Channels
Alternative Name(s) :
Potassium voltage-gated channel subfamily C member 2 Antibody, Kcnc2 Antibody, KSHIIIA Antibody
Size :
100 µg
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
S410-17
Immunogen :
Fusion protein amino acids 474-613 (Cytoplasmic C-terminus) of rat Kv3.2a
Immunogen Species :
Rat
Accession Number :
NP_631962.1
Swiss-Prot :
P22462
Applications :
WB IHC ICC/IF
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Abbreviation :
Hu Ms Rt
Species Reactivity Full Name :
Human Mouse Rat
Antibody Dilution :
WB (1:1000); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Storage Buffer :
PBS pH7.4, 50% glycerol, 0.1% sodium azide
Concentration :
1 mg/ml
Specificity :
Detects ~80-100kDa. Varies due to post-translational modifications.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-492D, RRID: AB_2702567
Certificate of Analysis :
A 1:100 dilution of SMC-492 was sufficient for detection of Kv3.2 in 20 µg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Cellular Localization :
Cell Membrane
Scientific Background :
Kv3.2, a member of the KCNC2 gene family, belongs to a group of potassium channels that contribute to the maintenance of cell volume, membrane potential, neuronal excitability and the secretion of transmitters, salt and hormones. Kv3.2 are predominantly expressed in neurons that fire at high frequencies, and in the fast spiking GABAergic interneurons of the neocortex, hippocampus, and caudate nucleus (1-3). They specifically functioning as a delayed rectifier activated by large membrane depolarizations (2, 4).
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-492-Kv32-Antibody-S410-17-ICC-IF-Human-Neuroblastoma-cell-line-SK-N-BE-60X-Composite-1.png SMC-492_Kv32_Antibody_S410-17_IHC_Human_Brain-Cortex_1.png SMC-492-Kv32-Antibody-S410-17-WB-Mouse-Rat-Brain-1.png
more info or order :
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.