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company name :
StressMarq Biosciences
product type :
antibody
product name :
FGFA/FHFA (pan) Antibody
catalog :
SMC-448D
quantity :
100 µg
price :
300.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S235-22
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
StressMarq Biosciences product webpage
product information
Catalog No :
SMC-448D
Product Name :
FGFA/FHFA (pan) Antibody
Description :
Mouse Anti-Human FGFA/FHFA (pan) Monoclonal IgG2b
Target :
FGF13
Conjugate :
Unconjugated
2021 List Price :
300.00 USD
Currency :
USD
Research Area(s) :
Cardiovascular System Angiogenesis Cardiovascular Growth Factors FGF Neuroscience Neurogenesis
Alternative Name(s) :
FGF-13 Antibody, FHF-2 Antibody, FGF13 Antibody, FHF2 Antibody, Acidic fibroblast growth factor Antibody, AFGF Antibody, Beta endothelial cell growth factor Antibody, Fibroblast growth factor homologous factor 2A Antibody, Fibroblast growth factor 13A Antibody, FGF13A Antibody, Beta-endothelial cell growth factor Antibody, ECGF Antibody, ECGFA Antibody, ECGFB Antibody, Endothelial Cell Growth Factor alpha Antibody, Endothelial Cell Growth Factor alpha Antibody, Endothelial Cell Growth Factor beta Antibody, FGF 1 Antibody, FGF alpha Antibody, FGFA Antibody, Fibroblast Growth Factor 1 Acidic Antibody, Fibroblast growth factor 1 Antibody, GLIO703 Antibody, HBGF 1 Antibody, HBGF1 Antibody, Heparin binding growth factor 1 Antibody, Heparin binding growth factor 1 precursor Antibody, Heparin-binding growth factor 1 Antibody
Size :
100 µg
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
S235-22
Immunogen :
Synthetic peptide amino acids 2-18 (AAAIASSLIRQKRQARE) of human FHF2A. 100% identical to rat, 94% identical to mouse. >80% identity with FGF12A/FHF1A, FGF14A/FHF4A and FGF11A/FHF3A.
Immunogen Species :
Human
Accession Number :
AAH34340
Swiss-Prot :
Q92913
Applications :
WB IHC ICC/IF
Host Species :
Mouse
Isotype :
IgG2b
Species Reactivity Abbreviation :
Hu Ms Rt
Species Reactivity Full Name :
Human Mouse Rat
Antibody Dilution :
WB (1:1000); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Storage Buffer :
PBS pH 7.4, 50% glycerol, 0.1% sodium azide
Concentration :
1 mg/ml
Specificity :
Detects ~30kDa. Does not cross-react with FGF13B/FHF2B. Cross reacts with FGF12A/FHF1A and FGF14A/FHF4A.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-448D, RRID: AB_2701811
Certificate of Analysis :
1 µg/ml of SMC-448 was sufficient for detection of FGFA/FHFA (pan) in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Cellular Localization :
Cell Projection Growth Cone Dendrite Nucleus Cytoplasm
Scientific Background :
FGF13(Fibroblast growth factor 13), also called FHF2 is a protein that in humans is encoded by the FGF13 gene.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF13is a large gene, extending over approximately 200 kb in Xq26.3, and contains at least 7 exons. By cytogenetic, FISH, and database analysis, Gecz et al. (1999) localized the FGF13 gene within a 400-kb duplication interval on chromosome Xq26.3. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located to a region associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a syndromal X-linked mental retardation, which suggests it may be a candidate gene for familial cases of the BFL syndrome. The function of this gene has not yet been determined. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
References :
1. Gecz, J., et al. (1999) Hum. Genet. 104: 56-63. 2. Smallwood, P. M., et al. (1996) Proc. Nat. Acad. Sci. 93: 9850-9857.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-448-FGFA-FHFA-pan-Antibody-S235-22-ICC-IF-Human-Neuroblastoma-cell-line-SK-N-BE-60X-Composite-1.png SMC-448-FGFA-FHFA-pan-Antibody-S235-22-WB-Rat-Brain-Membrane-1.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.