product summary
Loading...
company name :
StressMarq Biosciences
product type :
antibody
product name :
GluA1/GluR1 Antibody
catalog :
SMC-440D
quantity :
100 µg
price :
300.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S355-1
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
StressMarq Biosciences product webpage
product information
Catalog No :
SMC-440D
Product Name :
GluA1/GluR1 Antibody
Description :
Mouse Anti-Rat GluA1/GluR1 Glutamate Receptor Monoclonal IgG1
Target :
GluR1
Conjugate :
Unconjugated
2021 List Price :
300.00 USD
Currency :
USD
Research Area(s) :
Neuroscience Neurotransmitter Receptors Glutamate Receptors AMPA Receptors Cell Signaling
Alternative Name(s) :
AMPA 1 Antibody, AMPA selective glutamate receptor 1 Antibody, Glutamate receptor 1 Antibody, GluA1 Antibody, GLUH 1 Antibody, GluR K1 Antibody, GluRK1 Antibody, Glr-1 Antibody, Glur-1 Antibody, HIPA Antibody, Glur1 Antibody, GluR-A Antibody, AI853806 Antibody, 2900051M01Rik Antibody, GluRA Antibody, Glr1 Antibody, MGC13325 Antibody, GLUH1 Antibody, GluA1 Antibody, GLUR1 Antibody, HBGR1 Antibody, GLURA Antibody, gluR- Antibody, GluA1 Antibody, Glutamate receptor ionotropic AMPA 1 Antibody, Glutamate receptor ionotropic Antibody, Gria 1 Antibody, HBGR1 Antibody, OTTHUMP00000160643 Antibody, OTTHUMP00000165781 Antibody, OTTHUMP00000224241 Antibody, OTTHUMP00000224242 Antibody, OTTHUMP00000224243 Antibody
Size :
100 µg
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
S355-1
Immunogen :
Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1
Immunogen Species :
Rat
Accession Number :
NP_113796
Swiss-Prot :
P19490
Applications :
WB IHC ICC/IF
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Abbreviation :
Hu Ms Rt
Species Reactivity Full Name :
Human Mouse Rat
Antibody Dilution :
WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Storage Buffer :
PBS pH 7.4, 50% glycerol, 0.1% sodium azide
Concentration :
1 mg/ml
Specificity :
Detects ~100kDa. Does not cross-react with GluR2.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-440D, RRID: AB_2701667
Certificate of Analysis :
1 µg/ml of SMC-440 was sufficient for detection of GluA1/GluR1 in 20 µg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Cellular Localization :
Cell Membrane Endoplasmic Reticulum Cell Junction
Scientific Background :
Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3). GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration (3).
References :
1. Potier M.C., Spillantini M.G., Carter N.P. (1992) DNA Seq. 2(4): 211-218. 2. Puckett, C., et al. (1991) Proc. Nat. Acad. Sci. USA 88(17): 7557-7561. 3. Gregor, P., et al. (1993) Proc. Nat. Acad. Sci. USA 90: 3053-3057.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-440-GluA1-GluR1-Glutamate-Receptor-Antibody-S355-1-ICC-IF-Human-Neuroblastoma-cell-line-SK-N-BE-60X-Composite-1.png SMC-440_GluA1-GluR1_Antibody_S355-1_WB_Rat_Brain-Membrane_1.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.