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company name :
StressMarq Biosciences
product type :
antibody
product name :
mGluR1/5 Antibody
catalog :
SMC-419D
quantity :
100 µg
price :
300.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S75-3
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
StressMarq Biosciences product webpage
product information
Catalog No :
SMC-419D
Product Name :
mGluR1/5 Antibody
Description :
Mouse Anti-Rat mGluR1/5 glutamate receptor Monoclonal IgG2A
Target :
mGluR5
Conjugate :
Unconjugated
2021 List Price :
300.00 USD
Currency :
USD
Research Area(s) :
Neuroscience Neurotransmitter Receptors Glutamate Receptors Metabotropic Glutamate Receptors (mGluR) Cell Signaling Cancer
Alternative Name(s) :
mGluR Antibody, metabotropic glutamate receptor 5 Antibody, metabotropic glutamate receptor 1 Antibody, mGlu5 Antibody, mGlu1 Antibody, mGluR5 Antibody, mGluR1 Antibody, GPRC1E Antibody, GRM5 Antibody, Metabotropic glutamate receptor 5 variant F Antibody, Metabotropic glutamate receptor 5 variant G Antibody, Metabotropic glutamate receptor 5 variant H Antibody, Glutamate receptor metabotropic 5 Antibody
Size :
100 µg
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
S75-3
Immunogen :
Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b
Immunogen Species :
Rat
Accession Number :
NP_058708.1
Swiss-Prot :
P31424
Applications :
WB IHC ICC/IF IP
Host Species :
Mouse
Isotype :
IgG2A
Species Reactivity Abbreviation :
Hu Ms Rt
Species Reactivity Full Name :
Human Mouse Rat
Antibody Dilution :
WB (1:1000), IHC (1:1000), ICC/IF (1:1000); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Storage Buffer :
PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration :
1 mg/ml
Specificity :
Detects ~130kDa (both mGluR1 and mGluR5).
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-419D, RRID: AB_2701289
Certificate of Analysis :
1 µg/ml of SMC-419 was sufficient for detection of mGluR1/5 glutamate receptor in 20 µg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Cellular Localization :
Cell Membrane
Scientific Background :
The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers (1, 2).
References :
1. Mayer M.L. (2005) Current Opinion in Neurobio. 15(3): 282-288. 2. Keinane K., et al. (1990) Science. 249: 556-560.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-419_mGluR1-5-glutamate-receptor_Antibody_S75-3_ICC-IF_Human_SK-N-BE-Cells-Human-Neuroblastoma-cells_60X_Composite_1.png SMC-419_mGluR5_Antibody_S75-33_WB_Rat_Brain-Membrane_1.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.