product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
NALCN Antibody
catalog :
SMC-417
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S187-7
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
StressMarq Biosciences product webpage
citations: 3
Reference
Ferreira J, Amazu C, Puga Molina L, Ma X, England S, Santi C. SLO2.1/NALCN a sodium signaling complex that regulates uterine activity. iScience. 2021;24:103210 pubmed publisher
Yang Y, Ou M, Liu J, Zhao W, Zhuoma L, Liang Y, et al. Volatile Anesthetics Activate a Leak Sodium Conductance in Retrotrapezoid Nucleus Neurons to Maintain Breathing during Anesthesia in Mice. Anesthesiology. 2020;133:824-838 pubmed publisher
Amazu C, Ma X, Henkes C, Ferreira J, Santi C, England S. Progesterone and estrogen regulate NALCN expression in human myometrial smooth muscle cells. Am J Physiol Endocrinol Metab. 2020;318:E441-E452 pubmed publisher
image
image 1 :
StressMarq Biosciences SMC-417 image 1
Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-NALCN Monoclonal Antibody, Clone S187-7 (SMC-417). Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-NALCN Monoclonal Antibody (SMC-417) at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) NALCN Antibody. (D) Composite.
product information
Catalog No :
SMC-417
Product Name :
NALCN Antibody
Description :
Mouse Anti-Rat NALCN Monoclonal IgG1
Target :
NALCN
Research Area(s) :
Neuroscience Ion Channels Sodium Channels Sodium Leak Channels Potassium Channels Calcium Channels
Alternative Name(s) :
VGCNL1 Antibody, CanIon Antibody, Sodium leak channel non-selective protein Antibody, Voltage gated channel-like protein 1 Antibody, A530023G15Rik Antibody, bA430M15.1 Antibody, FLJ23913 Antibody, FLJ44659 Antibody, FLJ44764 Antibody, Four repeat voltage gated ion channel Antibody, MGC74524 Antibody, Putative 4 repeat voltage gated ion channel Antibody, Sodium leak channel non-selective protein Antibody
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
S187-7
Immunogen :
Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
Accession Number :
NP_705894.1
Swiss-Prot :
Q6Q760
Applications :
WB ICC/IF
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Medium :
Human Mouse Rat
Antibody Dilution :
WB (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Specificity :
Detects ~200kDa.
Cellular Localization :
Membrane
Size 1 :
100 µg
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.