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company name :
StressMarq Biosciences
product type :
antibody
product name :
TrpV3 Antibody
catalog :
SMC-334D
quantity :
100 µg
price :
300.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S15-39
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
StressMarq Biosciences product webpage
product information
Catalog No :
SMC-334D
Product Name :
TrpV3 Antibody
Description :
Mouse Anti-Rat TrpV3 Monoclonal IgG2a
Target :
TRPV3
Conjugate :
Unconjugated
2021 List Price :
300.00 USD
Currency :
USD
Research Area(s) :
Neuroscience Ion Channels Transient Receptor Potential (TRP) Channels
Alternative Name(s) :
VRL3 Antibody, vanilloid receptor 2 Antibody, transient receptor potential cation channel subfamily V member 3 Antibody, sensitive channel TRPV3 Antibody, 1110036I10Rik Antibody, MGC124324 Antibody, MGC124325 Antibody, Trpv3 heat sensitive channel Antibody, vanilloid receptor-related osmotically activated channel protein Antibody
Size :
100 µg
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
S15-39
Immunogen :
Synthetic peptide amino acids 458-474 (cytoplasmic C-terminus) of rat TrpV3
Immunogen Species :
Rat
Accession Number :
NP_001020928
Swiss-Prot :
Q4QYD9
Applications :
WB IHC ICC/IF IP AM
Host Species :
Mouse
Isotype :
IgG2a
Species Reactivity Abbreviation :
Hu Ms Rt
Species Reactivity Full Name :
Human Mouse Rat
Antibody Dilution :
WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Storage Buffer :
PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration :
1 mg/ml
Specificity :
Detects ~70kDa.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-334D, RRID: AB_2209275
Certificate of Analysis :
1 µg/ml of SMC-334 was sufficient for detection of TrpV3 in 10 µg of COS-1 cell lysate transiently transfected with TrpV3 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody
Cellular Localization :
Membrane
Scientific Background :
The TRPV3 protein belongs to a family of non-selective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermo sensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. The gene lies in close proximity to another family member (TRPV1) gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels (1, 2).
References :
1. Masamoto Y., Kawabata F., Fushiki T. (2009) Biosci. Biotechnol. Biochem. 73(5): 1021-1027. 2. Xiao R., et al. (2008) J Biol Chem. 283(10): 6162-6174.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-334_TrpV3_Antibody_S15-39_IHC_Mouse_backskin_1.png SMC-334_TrpV3_Antibody_S15-39_WB_Rat_brain-membrane-lysate_1.png SMC-334_TrpV3_Antibody_S15-39_ICC-IF_Human_HaCaT-cells_1.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.