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company name :
StressMarq Biosciences
product type :
antibody
product name :
GluN2B/NR2B Antibody
catalog :
SMC-333D
quantity :
100 µg
price :
300.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S59-20
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
StressMarq Biosciences product webpage
product information
Catalog No :
SMC-333D
Product Name :
GluN2B/NR2B Antibody
Description :
Mouse Anti-Rat GluN2B/NR2B Monoclonal IgG2a
Target :
NMDAR2B NMDA
Conjugate :
Unconjugated
2021 List Price :
300.00 USD
Currency :
USD
Research Area(s) :
Neuroscience Ion Channels Neurotransmitter Receptors Glutamate Receptors NMDA Receptors Neurodegeneration
Alternative Name(s) :
NMDAR2B Antibody, hNR3 Antibody, MGC142180 Antibody, glutamate receptor subunit epsilon-2 Antibody, NR3 Antibody, GluN2B Antibody, hNR3 Antibody, MRD6 Antibody, NMDAR2B Antibody, NR2B Antibody
Size :
100 µg
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
S59-20
Immunogen :
Fusion protein amino acids 20-271 (N-terminus) of rat NR2B
Immunogen Species :
Rat
Accession Number :
NP_036706.1
Swiss-Prot :
Q00960
Applications :
WB IHC ICC/IF IP AM
Host Species :
Mouse
Isotype :
IgG2a
Species Reactivity Abbreviation :
Hu Ms Rt
Species Reactivity Full Name :
Human Mouse Rat
Antibody Dilution :
WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Storage Buffer :
PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration :
1 mg/ml
Specificity :
Detects ~166kDa. No cross-reactivity against NR2A.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-333D, RRID: AB_10599356
Certificate of Analysis :
1 µg/ml of SMC-333 was sufficient for detection of NR2B/GluN2B in 10 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Cellular Localization :
Cell Membrane Cell Junction Synapse Postsynaptic Cell Membrane
Scientific Background :
NR2B/GluN2B containing receptors have been implicated in synaptic plasticity, memory formation and pain modulation (1). Studies suggest that the NR2B subunit of glutamate receptors may be potential targets for relieving pain; NR2B may be a probable target for anti-nociceptive drugs, and may also be useful as analgesics (2).
References :
1. Zhuo M. (2009) Mol Brain. 2(1): 4 2. Gurwitz D, and Weizman A. (2002) Drug Discovery Today, 7(7): 403-406.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-333_GluN2B-NR2B_Antibody_S59-20_IHC_Mouse_backskin_1.png SMC-333_GluN2B-NR2B_Antibody_S59-20_WB_Rat_brain-membrane-lysate_1.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.