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company name :
StressMarq Biosciences
product type :
antibody
product name :
Cav beta 2 Antibody
catalog :
SMC-332D
quantity :
100 µg
price :
300.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S8B-1
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
StressMarq Biosciences product webpage
product information
Catalog No :
SMC-332D
Product Name :
Cav beta 2 Antibody
Description :
Mouse Anti-Rat Cav beta 2 Monoclonal IgG1
Target :
CavBeta2
Conjugate :
Unconjugated
2021 List Price :
300.00 USD
Currency :
USD
Research Area(s) :
Neuroscience Ion Channels Calcium Channels Voltage-Gated Calcium Channels
Alternative Name(s) :
Cacnlb2 Antibody, cacnb2 Antibody, Voltage-dependent L-type calcium channel subunit beta-2 Antibody, CAB2 Antibody
Size :
100 µg
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
S8B-1
Immunogen :
Synthetic peptide amino acids 189-205 of rat CavBeta2
Immunogen Species :
Rat
Accession Number :
NP_446303
Swiss-Prot :
Q8VGC3
Applications :
WB IHC ICC/IF IP AM
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Abbreviation :
Hu Ms Rt
Species Reactivity Full Name :
Human Mouse Rat
Antibody Dilution :
WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Storage Buffer :
PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration :
1 mg/ml
Specificity :
Detects ~78 kDa. No cross reactivity against Cavβ1, Cavβ3, Cavβ4.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-332D, RRID: AB_2259513
Certificate of Analysis :
1 µg/ml of SMC-332 was sufficient for detection of Cavβ2 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody
Cellular Localization :
Cell Membrane Sarcolemma
Scientific Background :
Cav Beat subunits are involved in the transport of the pore forming alpha1 subunit to the plasma membrane (1). They also shield an ER Retention signal on the alpha1 subunit, thereby guiding the pore-forming subunit to the target membrane (2, 3). They also determine the biophysical properties of the calcium channel (3).
References :
1. Dolphin A.C. (2003) J Bioenerg. Biomembr. 35: 599-620. 2. Bichet D., et al. (2000) Neuron. 25: 177-190. 3. Xie M., et al. (2007) J Cell Biol. 178(3): 489-502.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-332_Cav-Beta2-Calcium-Channel_Antibody_S8b-1_IHC_Mouse_backskin_1.png SMC-332_Cav-Beta2-Calcium-Channel_Antibody_S8b-1_WB_Human_Cell-line-lysates_1.png SMC-332_Cav-Beta2-Calcium-Channel_Antibody_S8b-1_ICC-IF_Human_HaCaT-cells_1.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.