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company name :
StressMarq Biosciences
product type :
antibody
product name :
Slo3 Antibody
catalog :
SMC-326D
quantity :
100 µg
price :
300.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S2-16
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
StressMarq Biosciences product webpage
product information
Catalog No :
SMC-326D
Product Name :
Slo3 Antibody
Description :
Mouse Anti-Mouse Slo3 Monoclonal IgG2b
Target :
Slo3
Conjugate :
Unconjugated
2021 List Price :
300.00 USD
Currency :
USD
Research Area(s) :
Neuroscience Ion Channels Potassium Channels Calcium-Activated Potassium Channels
Alternative Name(s) :
Kcnma3 Antibody, mSlo3 Antibody, Slo3 Antibody, KCa5 Antibody, KCNMA3 Antibody, potassium channel subfamily U member 1 Antibody, Slowpoke homolog 3 Antibody, KCa5.1 Antibody, KCNMC1Calcium-activated potassium channel Antibody, subfamily M subunit alpha-3 Antibody, Calcium-activated potassium channel subunit alpha-3 Antibody, potassium channel Antibody, subfamily U Antibody, member 1 Antibody
Size :
100 µg
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
S2-16
Immunogen :
Fusion protein amino acids 1052-1121 of mouse Slo3
Immunogen Species :
Mouse
Accession Number :
NP_032458.3
Swiss-Prot :
O54982
Applications :
WB IHC ICC/IF AM
Host Species :
Mouse
Isotype :
IgG2b
Species Reactivity Abbreviation :
Hu Ms Rt
Species Reactivity Full Name :
Human Mouse Rat
Antibody Dilution :
WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Storage Buffer :
PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration :
1 mg/ml
Specificity :
Detects ~115kDa.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-326D, RRID: AB_2249597
Certificate of Analysis :
1 µg/ml of SMC-326 was sufficient for detection of Slo3 in 10 µg of mouse brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Cellular Localization :
Cell Membrane
Scientific Background :
The Slo3 channel is a novel potassium channel abundantly expressed in mammalian speramtocytes- tests have shown that it is expressed in both mouse and human testis (3). It represents a new and unique type of potassium channel that is regulated by both intracellular pH and membrane voltage (1). Because of its sensitivity to both pH and voltage, Slo3 may play a role in alkalization-mediated K(+) fluxes associated with sperm capacitation (2).
References :
1. Schreiber M., et al. (1998) J Biol Chem. 273 (6): 3509-3516. 2. Tang Q.Y., Zhang Z., Xia X.M. and Lingle C.J. (2010) Epub: Channels (Austin) 4(1).
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-326_Slo3-Potassium-Channel_Antibody_S2-16_ICC-IF_Human_HaCaT-cells_1.png SMC-326_Slo3-Potassium-Channel_Antibody_S2-16_WB_Rat_Cell-line-mix_1.png SMC-326_Slo3-Potassium-Channel_Antibody_S2-16_IHC_Mouse_backskin_1.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.