This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
StressMarq Biosciences
product type :
antibody
product name :
Cav beta 1 Antibody
catalog :
SMC-317D
quantity :
100 µg
price :
300.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S7-18
reactivity :
rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
product information
Catalog No :
SMC-317D
Product Name :
Cav beta 1 Antibody
Description :
Mouse Anti-Rat Cav beta 1 Monoclonal IgG1
Target :
CACNB1
Conjugate :
Unconjugated
2021 List Price :
300.00 USD
Currency :
USD
Research Area(s) :
Neuroscience Ion Channels Calcium Channels Voltage-Gated Calcium Channels Cancer Cell Signaling Protein Trafficking
Alternative Name(s) :
CACNB1 Antibody, CAB1 Antibody, CACNLB1 Antibody, voltage dependent L type calcium channel beta 1 subunit Antibody
Size :
100 µg
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
S7-18
Immunogen :
Synthetic peptide amino acids 19-34 of rat CavB1
Immunogen Species :
Rat
Accession Number :
NP_059042
Swiss-Prot :
P54283
Applications :
WB IHC ICC/IF IP AM
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Abbreviation :
Hu Ms Rt
Species Reactivity Full Name :
Human Mouse Rat
Antibody Dilution :
WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Storage Buffer :
PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration :
1 mg/ml
Specificity :
Detects ~80, 55kDa. No cross-reactivity against Cav Beta4.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-317D, RRID: AB_1633309
Certificate of Analysis :
1 µg/ml of SMC-317 was sufficient for detection of Cavβ1 in 10 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Cellular Localization :
Cell Membrane
Scientific Background :
Calcium channel, voltage-dependent, beta 1 subunit, also known as CACNB1, is a human gene. The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified (1, 2).
References :
1. www.iochannels.org 2. Leyris J.P., et al. (2009) Faseb J. EPub.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-317_CACNB1-Calcium-Channel_Antibody_S7-18_IHC_Human_hippocampus_1.png SMC-317_CACNB1-Calcium-Channel_Antibody_S7-18_WB_Rat_brain-membrane-lysate_1.png
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.