product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
TrpM7 Antibody
catalog :
SMC-316
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S74
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
StressMarq Biosciences product webpage
citations: 3
Reference
Newton H, Gawali V, Chimote A, Lehn M, Palackdharry S, Hinrichs B, et al. PD1 blockade enhances K+ channel activity, Ca2+ signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer. J Immunother Cancer. 2020;8: pubmed publisher
Kamermans A, Planting K, Jalink K, van Horssen J, de Vries H. Reactive astrocytes in multiple sclerosis impair neuronal outgrowth through TRPM7-mediated chondroitin sulfate proteoglycan production. Glia. 2019;67:68-77 pubmed publisher
Ogunrinde A, Pereira R, Beaton N, Lam D, Whetstone C, Hill C. Hepatocellular differentiation status is characterized by distinct subnuclear localization and form of the chanzyme TRPM7. Differentiation. 2017;96:15-25 pubmed publisher
image
image 1 :
StressMarq Biosciences SMC-316 image 1
Immunohistochemistry analysis using Mouse Anti-TrpM7 Monoclonal Antibody, Clone S74 (SMC-316). Tissue: Brain Slice. Species: Mouse. Fixation: 10% Formalin Solution for 12-24 hours at RT. Primary Antibody: Mouse Anti-TrpM7 Monoclonal Antibody (SMC-316) at 1:1000 for 1 hour at RT. Secondary Antibody: HRP/DAB Detection System: Biotinylated Goat Anti-Mouse, Streptavidin Peroxidase, DAB Chromogen (brown) for 30 minutes at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 250-500 µl for 5 minutes at RT. Localization: Nuclear staining of both neurons and glia.
product information
Catalog No :
SMC-316
Product Name :
TrpM7 Antibody
Description :
Mouse Anti-Mouse TrpM7 Monoclonal IgG1
Target :
TRPM7
Research Area(s) :
Neuroscience Ion Channels Transient Receptor Potential (TRP) Channels Neuroscience Neurodegeneration Parkinson's Disease ALS Disease Alzheimer's Disease
Alternative Name(s) :
CHAK antibody, CHAK1 antibody, Channel kinase 1 antibody, Channel-kinase 1 antibody, Long transient receptor potential channel 7 antibody, LTrpC-7 antibody, LTRPC7 antibody, Transient receptor potential cation channel subfamily M member 7 antibody, TRP PLIK antibody, TRPM7 antibody, TRPM7_HUMAN antibody
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
S74
Immunogen :
Fusion protein amino acids 1817-1863 (C- terminus) of mouse TrpM7
Accession Number :
NP_001157797.1
Swiss-Prot :
Q923J1
Applications :
WB (for use in transiently transfected cells only) IHC ICC/IF AM
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Medium :
Human Mouse Rat
Antibody Dilution :
WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Specificity :
Detects ~220kDa in extracts of cells transiently transfected with TrpM7. No cross-reactivity against TrpM6.
Cellular Localization :
Membrane
Size 1 :
100 µg
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.