product summary
Loading...
company name :
StressMarq Biosciences
product type :
antibody
product name :
KCNQ1 Antibody
catalog :
SMC-307D
quantity :
100 µg
price :
300.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S37A-10
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
StressMarq Biosciences product webpage
product information
Catalog No :
SMC-307D
Product Name :
KCNQ1 Antibody
Description :
Mouse Anti-Human KCNQ1 Monoclonal IgG1
Target :
KCNQ1
Conjugate :
Unconjugated
2021 List Price :
300.00 USD
Currency :
USD
Research Area(s) :
Neuroscience Ion Channels Potassium Channels Voltage-Gated Potassium Channels cardiovascular System Heart
Alternative Name(s) :
ATFB1 Antibody, ATFB3 Antibody, FLJ26167 Antibody, IKs producing slow voltage-gated potassium channel subunit alpha Antibody, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1 Antibody, Jervell and Lange-Nielsen syndrome 1 Antibody, JLNS1 Antibody, KCNA8 Antibody, KCNA9 Antibody, KCNQ1 Antibody, KCNQ1_HUMAN Antibody, kidney and cardiac voltage dependend K+ channel Antibody, KQT-like 1 Antibody, Kv1.9 Antibody, Kv7.1 Antibody, KVLQT1 Antibody, long (electrocardiographic) QT syndrome Antibody, Ward-Romano syndrome 1 Antibody, LQT Antibody, LQT1 Antibody, Potassium voltage-gated channel subfamily KQT member 1 Antibody, potassium voltage-gated channel KQT-like subfamily member 1 Antibody, RWS Antibody, slow delayed rectifier channel subunit Antibody, SQT2 Antibody, Voltage-gated potassium channel subunit Kv7.1 Antibody, WRS Antibody
Size :
100 µg
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
S37A-10
Immunogen :
Fusion protein amino acids 2-101 of human KCNQ1
Immunogen Species :
Human
Accession Number :
NP_000209.2
Swiss-Prot :
P51787
Applications :
WB IHC ICC/IF IP AM
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Abbreviation :
Hu Ms Rt Hm
Species Reactivity Full Name :
Human Mouse Rat Hamster
Antibody Dilution :
WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Storage Buffer :
PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration :
1 mg/ml
Specificity :
Detects ~75kDa.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-307D, RRID: AB_2249571
Certificate of Analysis :
1 µg/ml of SMC-307 was sufficient for detection of KCNQ1 in 10 µg of COS-1 cell lysate transiently expressing KCNQ1 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Cellular Localization :
Cell Membrane Cytoplasmic Vesicle Membrane
Scientific Background :
Kv7.1 (KvLQT1) is a potassium channel protein coded for by the gene KCNQ1. Kv7.1 is present in the cell membranes of cardiac muscle tissue and in inner ear neurons (1) among other tissues. In the cardiac cells, Kv7.1 mediates the IKs (or slow delayed rectifying K+) current that contributes to the repolarization of the cell, terminating the cardiac action potential and thereby the heart's contraction (2, 3).
References :
1. Lang F., Vallon V., Knipper M., Wagenmann P. (2007) Am J Physiol. 293(4): C1187-1208. 2. Kurokawa J., et al. (2009) Channels (Austin). 3(1): 16-24. 3. Silva J., and Rudy Y. (2005) Circulation. 112(10): 1384-1391.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-307_KCNQ1_Antibody_S37A-10_IHC_Human_hippocampus_2.png SMC-307_KCNQ1_Antibody_S37A-10_WB_Human_Cell-lysates_1.png SMC-307_KCNQ1_Antibody_S37A-10_IHC_Mouse_Brain-Slice_1.png SMC-307_KCNQ1_Antibody_S37A-10_WB_Hampster_T-CHO-cell-lysate_1.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.