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company name :
StressMarq Biosciences
product type :
antibody
product name :
Cav3.2 Antibody
catalog :
SMC-303D
quantity :
100 µg
price :
300.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
S55-10
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
StressMarq Biosciences product webpage
product information
Catalog No :
SMC-303D
Product Name :
Cav3.2 Antibody
Description :
Mouse Anti-Human Cav3.2 Monoclonal IgG1
Target :
Cav3.2
Conjugate :
Unconjugated
2021 List Price :
300.00 USD
Currency :
USD
Research Area(s) :
Neuroscience Ion Channels Calcium Channels Voltage-Gated Calcium Channels Cancer Cell Signaling
Alternative Name(s) :
Cav3.2 Antibody, CACNA1H Antibody, CACNA1HB Antibody, calcium channel Antibody, voltage-dependent Antibody, T type Antibody, alpha 1H subunit Antibody, calcium channel Antibody, voltage-dependent Antibody, T type Antibody, alpha 1Hb subunit Antibody, ECA6 Antibody, EIG6 Antibody, FLJ90484 Antibody, Low-voltage-activated calcium channel alpha1 3.2 subunit Antibody, low-voltage-activated calcium channel alpha13.2 subunit Antibody, voltage dependent t-type calcium channel alpha-1H subunit Antibody, voltage-dependent T-type calcium channel subunit alpha-1H Antibody, voltage-gated calcium channel alpha subunit Cav3.2 Antibody, voltage-gated calcium channel alpha subunit CavT.2 Antibody, Voltage-gated calcium channel subunit alpha Cav3.2 Antibody
Size :
100 µg
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
S55-10
Immunogen :
Fusion protein amino acids 1019-1293 (II-III loop) of human Cav3.2
Immunogen Species :
Human
Accession Number :
NP_001005407.1
Swiss-Prot :
O95180
Applications :
WB IHC ICC/IF IP AM
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Abbreviation :
Hu Ms Rt
Species Reactivity Full Name :
Human Mouse Rat
Antibody Dilution :
WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Storage Buffer :
PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration :
1 mg/ml
Specificity :
Detects ~260kDa. No cross-reactivity against Cav1.3.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-303D, RRID: AB_2069540
Certificate of Analysis :
1 µg/ml of SMC-303 was sufficient for detection of Cav3.2 in 10 µg of HEK cell lysate expressing Cav3.2 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Cellular Localization :
Membrane
Scientific Background :
CaV3.2 is a protein which in humans is encoded by the CACNA1H gene. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (1, 2). Studies also suggest that the up-regulations of CaV3.2 may participate in the progression of prostate cancer toward an androgen-independent stage (3).
References :
1. Chen Y., et al. (2003) Ann. Neurol. 54(2): 239–43. 2. Khosravani H., et al. (2004) J Biol Chem. 279(11): 9681-9684. 3. Gackiere F., et al. (2008) J Biol Chem. 283(28): 19872.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-303_CaV3.2-Calcium-Channel_Antibody_S55-10_IHC_Human_hippocampus_2.png SMC-303_CaV3.2-Calcium-channel_Antibody_S55-10_IHC_human_frozen-brain-section_1.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.