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company name :
StressMarq Biosciences
product type :
antibody
product name :
Vimentin Antibody
catalog :
SMC-261D
quantity :
100 µl
price :
260.00 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1A7
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
StressMarq Biosciences product webpage
product information
Catalog No :
SMC-261D
Product Name :
Vimentin Antibody
Description :
Mouse Anti-Human Vimentin Monoclonal IgG1
Target :
Vimentin
Conjugate :
Unconjugated
2021 List Price :
260.00 USD
Currency :
USD
Research Area(s) :
Neuroscience Neurogenesis Cell Signaling Cytoskeleton Intermediate Filaments Vimentin Neuroscience Cell Markers Neuron Markers Neural Stem Cell Markers Stem Cells Lineage Markers Endoderm Cancer Tumor Biomarkers Neuroregeneration
Alternative Name(s) :
CTRCT30 Antibody, Epididymis luminal protein 113 Antibody, HEL113 Antibody, VIM Antibody, VIME_HUMAN Antibody, Vimentin Antibody
Size :
100 µl
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
1A7
Immunogen :
Full-length protein.
Immunogen Species :
Human
Accession Number :
NP_003371.2
Swiss-Prot :
P08670
Applications :
WB ICC/IF
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Abbreviation :
Hu Ms Rt
Species Reactivity Full Name :
Human Mouse Rat
Antibody Dilution :
WB (1:2000), ICC/IF (1:200); optimal dilutions for assays should be determined by the user.
Purification :
Peptide Affinity Purified
Storage Buffer :
PBS, pH 7.4, 50% glyercol, 0.05% sodium azide
Specificity :
Antibody can detects endogenous Vimentin protein.
Storage Temperature :
-20ºC
Shipping Temperature :
Blue Ice or 4ºC
Cite this Product :
StressMarq Biosciences Cat# SMC-261D, RRID: AB_2699844
Certificate of Analysis :
A 1:2000 dilution of SMC-261 was sufficient for detection of Vimentin in 10 µg of Human, Mouse, Rat, HeLa, Brain cell lysates by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.
Cellular Localization :
Cytoplasm
Scientific Background :
Vimentin is a type III intermediate filament (IF) protein. All IF proteins are highly expressed and vimentin is the major cytoskeletal component of mesechymal, and therefore Vimentin is used as a marker of mesenchymally-derived cells or cells undergoing EMT during both normal development and metastic progression. Functionally it also serves a significant role in supporting and anchording the organelles in the cytosol. Clinical significance includes being used as a sarcoma tumor marker, and it has also been used in the diagnosis of rheumatoid arthritis.
References :
1. Katsumoto T., Mitsushima A., Kurimura T. (1990). Biol Cell. 68(2): 139–146. 2. Leader M, Collins M, Patel J, Henry K (1987). Histopathology 11(1): 63–72. 3. Immunohistochemistry from the Washington Animal Disease Diagnostic laboratory (WADDL)of the College of Veterinary Medicine, Washington State University. Retrieved 2009-03-14.
Field of Use :
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Image Filenames :
SMC-261_Vimentin_Antibody_WB_Human_Mous
e_Rat_HeLa_Brain_1.png
SMC-261_Vimentin_Antibody_ICC-IF_Human_HeLa_1.png
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.