product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
HSP70 Antibody
catalog :
SMC-249
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1H11
reactivity :
human, mouse, rat, bovine
application :
western blot, immunocytochemistry, flow cytometry, FACS
more info or order :
StressMarq Biosciences product webpage
citations: 2
Reference
Portillo J, Van Grol J, Saffo S, Lopez Corcino Y, Rodríguez M, Fox B, et al. CD40 in endothelial cells restricts neural tissue invasion by Toxoplasma gondii. Infect Immun. 2019;: pubmed publisher
Barreca M, Spinello W, Cavalieri V, Turturici G, Sconzo G, Kaur P, et al. Extracellular Hsp70 Enhances Mesoangioblast Migration via an Autocrine Signaling Pathway. J Cell Physiol. 2017;232:1845-1861 pubmed publisher
image
image 1 :
StressMarq Biosciences SMC-249 image 1
Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-HSP70 Monoclonal Antibody, Clone 1H11 (SMC-249). Tissue: HCT116 cells. Species: Human. Fixation: 4% Formaldehyde. Primary Antibody: Mouse Anti-HSP70 Monoclonal Antibody (SMC-249) at 1:100. Counterstain: Wheat germ agglutinin Texas red membrane marker; DAPI (blue) nuclear stain. Localization: Cell surface, cell membrane. (A) DAPI nuclear stain. (B) Wheat germ agglutinin Texas red. (C) HSP70 Antibody. (D) Composite. Courtesy of: Lawrence Hightower, Charles Giardina, and Didem Ozcan from University of Connecticut.
product information
Catalog No :
SMC-249
Product Name :
HSP70 Antibody
Description :
Mouse Anti-Human Cell Membrane HSP70 Monoclonal IgG1
Target :
HSP70
Research Area(s) :
Cell Signaling Protein Trafficking Chaperone Proteins Cancer Tumor Biomarkers Heat Shock
Alternative Name(s) :
HSP70 1 Antibody, HSP70 2 Antibody, HSP70.1 Antibody, HSP72 Antibody, HSPA1 Antibody, HSPA1A Antibody, HSPA1B Antibody
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
1H11
Immunogen :
Human native HSP70 protein
Accession Number :
NP_005336.3
Swiss-Prot :
P0DMV8/P0DMV9
Applications :
WB ICC/IF FCM FACS
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Medium :
Human Mouse Rat Bovine Pig
Antibody Dilution :
WB (1:1000), ICC/IF (1:100), FACS (1:250); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Specificity :
Conformation-specific antibody for membrane-bound HSP70. Binds to cell surface HSP70 without permeabilization of cell membrane in tumor cell lines. Does not bind to intracellular HSP70 at low concentrations. Cross-reacts with HSC70. Detects a ~70 kDa band in Western Blot.
Cellular Localization :
Cell membrane
Tissue Specificity :
Induced by heat shock.
Size 1 :
100 µg
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.