product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
Alpha B Crystallin Antibody
catalog :
SMC-165
quantity :
50 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3A10.C9
reactivity :
human, rat, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
more info or order :
StressMarq Biosciences product webpage
citations: 4
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human
Kötter S, Unger A, Hamdani N, Lang P, Vorgerd M, Nagel Steger L, et al. Human myocytes are protected from titin aggregation-induced stiffening by small heat shock proteins. J Cell Biol. 2014;204:187-202 pubmed publisher
Winter L, Unger A, Berwanger C, Sporrer M, Turk M, Chevessier F, et al. Imbalances in protein homeostasis caused by mutant desmin. Neuropathol Appl Neurobiol. 2018;: pubmed publisher
Unger A, Beckendorf L, Böhme P, Kley R, von Frieling Salewsky M, Lochmuller H, et al. Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function. Acta Neuropathol Commun. 2017;5:72 pubmed publisher
Mymrikov E, Daake M, Richter B, Haslbeck M, Buchner J. The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins. J Biol Chem. 2017;292:672-684 pubmed publisher
image
image 1 :
StressMarq Biosciences SMC-165 image 1
Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Alpha B Crystallin Monoclonal Antibody, Clone 3A10.C9 (SMC-165). Tissue: Neuroblastoma cell line (SK-N-BE). Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-Alpha B Crystallin Monoclonal Antibody (SMC-165) at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Magnification: 60X. (A) DAPI (blue) nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) Alpha B Crystallin Antibody. (D) Composite.
product information
Catalog No :
SMC-165
Product Name :
Alpha B Crystallin Antibody
Description :
Mouse Anti-Human Alpha B Crystallin Monoclonal IgG1
Target :
Alpha B Crystallin
Research Area(s) :
Cancer Heat Shock Cell Signaling Protein Trafficking Chaperone Proteins Neuroscience
Alternative Name(s) :
AACRYA Antibody, Alpha crystallin B chain Antibody, CRYA2 Antibody, CRYAB Antibody, CTPP2 Antibody, HSPB5 Antibody, NY REN 27 antigen Antibody
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
3A10.C9
Immunogen :
Native Alpha B Crystallin
Accession Number :
NP_001876.1
Swiss-Prot :
P02511
Applications :
WB IHC ELISA ICC/IF
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Medium :
Human Rat Bovine
Antibody Dilution :
WB (1:2000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Specificity :
Detects ~20kDa (predicted mol.weight is ~21kDa). Does not cross-react with αA-crystallin, βL-crystallin, ΒH-crystallin, γ-crystallin, HSP25, HSP27 or HSP47 proteins.
Cellular Localization :
Cytoplasm Nucleus
Size 1 :
50 µg
Size 2 :
200 µg
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.