product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
HSP90 (total) Antibody
catalog :
SMC-149
quantity :
50 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4F3.E8
reactivity :
human, mouse, rat, Canadian hard winter wheat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 8c
Blair L, Criado Marrero M, Zheng D, Wang X, Kamath S, Nordhues B, et al. The Disease-Associated Chaperone FKBP51 Impairs Cognitive Function by Accelerating AMPA Receptor Recycling. Eneuro. 2019;6: pubmed publisher
  • immunoprecipitation; Canadian hard winter wheat
Fellerer C, Schweiger R, Sch ngruber K, Soll J, Schwenkert S. Cytosolic HSP90 cochaperones HOP and FKBP interact with freshly synthesized chloroplast preproteins of Arabidopsis. Mol Plant. 2011;4:1133-45 pubmed publisher
Holmes B, Benavides Serrato A, Saunders J, Kumar S, Nishimura R, Gera J. mTORC2-mediated direct phosphorylation regulates YAP activity promoting glioblastoma growth and invasive characteristics. Neoplasia. 2021;23:951-965 pubmed publisher
Mediani L, Antoniani F, Galli V, Vinet J, Carrá A, Bigi I, et al. Hsp90-mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling. EMBO Rep. 2021;22:e51740 pubmed publisher
Serlidaki D, van Waarde M, Rohland L, Wentink A, Dekker S, Kamphuis M, et al. Functional diversity between HSP70 paralogs caused by variable interactions with specific co-chaperones. J Biol Chem. 2020;295:7301-7316 pubmed publisher
Bhatti M, Dinn S, Miskiewicz E, MacPhee D. Expression of heat shock factor 1, heat shock protein 90 and associated signaling proteins in pregnant rat myometrium: Implications for myometrial proliferation. Reprod Biol. 2019;19:374-385 pubmed publisher
Kim Chiaw P, Hantouche C, Wong M, Matthes E, Robert R, Hanrahan J, et al. Hsp70 and DNAJA2 limit CFTR levels through degradation. PLoS ONE. 2019;14:e0220984 pubmed publisher
Shelton L, Baker J, Zheng D, Sullivan L, Solanki P, Webster J, et al. Hsp90 activator Aha1 drives production of pathological tau aggregates. Proc Natl Acad Sci U S A. 2017;114:9707-9712 pubmed publisher
Wolfmeier H, Radecke J, Schoenauer R, Koeffel R, Babiychuk V, Drücker P, et al. Active release of pneumolysin prepores and pores by mammalian cells undergoing a Streptococcus pneumoniae attack. Biochim Biophys Acta. 2016;1860:2498-2509 pubmed publisher
O Brien K, Lowry M, Corcoran C, Martinez V, Daly M, Rani S, et al. miR-134 in extracellular vesicles reduces triple-negative breast cancer aggression and increases drug sensitivity. Oncotarget. 2015;6:32774-89 pubmed publisher
image
image 1 :
StressMarq Biosciences SMC-149 image 1
Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Hsp90 Monoclonal Antibody, Clone 4F3.E8 (SMC-149). Tissue: HaCaT cells. Species: Human. Fixation: Cold 100% methanol for 10 minutes at -20°C. Primary Antibody: Mouse Anti-Hsp90 Monoclonal Antibody (SMC-149) at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT.
product information
Catalog No :
SMC-149
Product Name :
HSP90 (total) Antibody
Description :
Mouse Anti-Human HSP90 (total) Monoclonal IgG2a
Target :
HSP90
Research Area(s) :
Cancer Heat Shock Cell Signaling Protein Trafficking Chaperone Proteins Cancer Tumor Biomarkers
Alternative Name(s) :
HSP84 Antibody, HSP86 Antibody, HSP90A Antibody, HSP90AA1 Antibody, HSP90AB1 Antibody, HSP90B Antibody, HSPC1 Antibody, HSPC2 Antibody, HSPCAL1 Antibody, HSPCAL4 Antibody
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
4F3.E8
Immunogen :
Recombinant Human HSP90 purified from E.coli
Accession Number :
NP_001017963.2
Swiss-Prot :
P07900
Applications :
WB IHC ICC/IF IP ELISA
Host Species :
Mouse
Isotype :
IgG2a
Species Reactivity Medium :
Human Mouse Rat Plant
Antibody Dilution :
WB (1:2000), IHC (1:100), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Specificity :
Detects ~90kDa. This antibody detects both α and β forms of HSP90 equally well.
Cellular Localization :
Cytoplasm Melanosome
Size 1 :
50 µg
Size 2 :
200 µg
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.