product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
HSP90 alpha Antibody
catalog :
SMC-147
quantity :
50 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2G5.G3
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
StressMarq Biosciences product webpage
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; human
Hunter M, O Hagan K, Kenyon A, Dhanani K, Prinsloo E, Edkins A. Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells. PLoS ONE. 2014;9:e86842 pubmed publisher
Mediani L, Antoniani F, Galli V, Vinet J, Carrá A, Bigi I, et al. Hsp90-mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling. EMBO Rep. 2021;22:e51740 pubmed publisher
Quel N, Pinheiro G, Rodrigues L, Barbosa L, Houry W, Ramos C. Heat shock protein 90 kDa (Hsp90) from Aedes aegypti has an open conformation and is expressed under heat stress. Int J Biol Macromol. 2020;156:522-530 pubmed publisher
Wang J, Grishin A, Ford H. Experimental Anti-Inflammatory Drug Semapimod Inhibits TLR Signaling by Targeting the TLR Chaperone gp96. J Immunol. 2016;196:5130-7 pubmed publisher
Ortega L, Calvillo M, Luna F, Perez Severiano F, Rubio Osornio M, Guevara J, et al. 17-AAG improves cognitive process and increases heat shock protein response in a model lesion with A?25-35. Neuropeptides. 2014;48:221-32 pubmed publisher
image
image 1 :
StressMarq Biosciences SMC-147 image 1
Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone 2G5.G3 (SMC-147). Tissue: HaCaT cells. Species: Human. Fixation: Cold 100% methanol for 10 minutes at -20°C. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody (SMC-147) at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT.
product information
Catalog No :
SMC-147
Product Name :
HSP90 alpha Antibody
Description :
Mouse Anti-Human HSP90 alpha Monoclonal IgG1
Target :
HSP90 alpha
Research Area(s) :
Cancer Heat Shock Cell Signaling Protein Trafficking Chaperone Proteins Cancer Tumor Biomarkers
Alternative Name(s) :
HSP86 Antibody, HSP89A Antibody, HSP90AA1 Antibody, HSP90Alpha Antibody, HSPC1 Antibody, HSPCA Antibody, HSPCAL3 Antibody
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
2G5.G3
Immunogen :
Recombinant Full Length Human HSP90alpha Protein
Accession Number :
NP_001017963.2
Swiss-Prot :
P07900
Applications :
WB IHC ICC/IF IP ELISA
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Medium :
Human Mouse Rat
Antibody Dilution :
WB (1:2000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Specificity :
Detects ~90kDa. HSP90α-specific (>96% α-specific by ELISA)
Cellular Localization :
Cytoplasm Melanosome
Size 1 :
50 µg
Size 2 :
200 µg
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.