product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
HO-1 Antibody
catalog :
SMC-131
quantity :
25 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1F12-A6
reactivity :
human, mouse, rat, dogs, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; mouse
Al Rifai N, Rücker H, Amslinger S. Opening or closing the lock? When reactivity is the key to biological activity. Chemistry. 2013;19:15384-95 pubmed publisher
Taira J, Ogi T. Induction of Antioxidant Protein HO-1 Through Nrf2-ARE Signaling Due to Pteryxin in Peucedanum Japonicum Thunb in RAW264.7 Macrophage Cells. Antioxidants (Basel). 2019;8: pubmed publisher
Wang H, Zhang Y, Xia F, Zhang W, Chen P, Yang G. Protective effect of silencing Stat1 on high glucose-induced podocytes injury via Forkhead transcription factor O1-regulated the oxidative stress response. BMC Mol Cell Biol. 2019;20:27 pubmed publisher
Yamaguchi Y, Kanzaki H, Katsumata Y, Itohiya K, Fukaya S, Miyamoto Y, et al. Dimethyl fumarate inhibits osteoclasts via attenuation of reactive oxygen species signalling by augmented antioxidation. J Cell Mol Med. 2018;22:1138-1147 pubmed publisher
Kanzaki H, Shinohara F, Itohiya Kasuya K, Ishikawa M, Nakamura Y. Nrf2 activation attenuates both orthodontic tooth movement and relapse. J Dent Res. 2015;94:787-94 pubmed publisher
Kanzaki H, Shinohara F, Kajiya M, Fukaya S, Miyamoto Y, Nakamura Y. Nuclear Nrf2 induction by protein transduction attenuates osteoclastogenesis. Free Radic Biol Med. 2014;77:239-48 pubmed publisher
image
image 1 :
StressMarq Biosciences SMC-131 image 1
Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-HO-1 Monoclonal Antibody, Clone 1F12-A6 (SMC-131). Tissue: Cervical cancer cell line (HeLa). Species: Human. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Mouse Anti-HO-1 Monoclonal Antibody (SMC-131) at 1:100 for 12 hours at 4°C. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:200 for 2 hours at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 2 hours at RT. Localization: Microsome. Endoplasmic reticulum. Localizes to the nucleus upon hypoxia. Magnification: 100x. (A) DAPI (blue) nuclear stain. (B) Anti-HO-1 Antibody. (C) Composite.
product information
Catalog No :
SMC-131
Product Name :
HO-1 Antibody
Description :
Mouse Anti-Human HO-1 Monoclonal IgG1 Kappa
Target :
HO-1
Research Area(s) :
Cancer Oxidative Stress Neuroscience Neurodegeneration Alzheimer's Disease Cardiovascular System Blood Platelets Cell Signaling Epigenetics and Nuclear Signaling Nuclear Signaling Pathways NFkB Pathway Cardiovascular System Atherosclerosis Vascular Inflammation Inflammatory Mediators Cardiovascular System Vasculature Endothelium Cancer Cancer Metabolism Response to Hypoxia Cell Signaling Metabolism Metabolism processes Hypoxia
Alternative Name(s) :
HSP32 Antibody, HMOX1 Antibody, Heme oxygenase 1 Antibody, HO Antibody, HO1 Antibody, , 32 kD antibody, bK286B10 antibody, D8Wsu38e antibody, heat shock protein 32 kD antibody, heat shock protein 32kD antibody, Heat shock protein antibody, Heme oxygenase (decycling) 1 antibody, Heme oxygenase 1 antibody, Hemox antibody, HMOX 1 antibody, Hmox antibody, Hmox1 antibody, HMOX1_HUMAN antibody, HO 1 antibody, HO antibody, HO-1 antibody, HO1 antibody, Hsp32 antibody
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
1F12-A6
Immunogen :
Human HO-1 synthetic peptide, amino acids 1-30
Accession Number :
NP_002124.1
Swiss-Prot :
P09601
Applications :
WB IHC ICC/IF IP ELISA
Host Species :
Mouse
Isotype :
IgG1 Kappa
Species Reactivity Medium :
Human Mouse Rat Bovine Dog Guinea Pig Hamster Monkey Pig Rabbit
Antibody Dilution :
WB (1:1000), IHC (1:100), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Specificity :
Detects 32kDa. Does not cross-react with HO-2.
Cellular Localization :
Microsome Endoplasmic Reticulum
Size 1 :
25 µg
Size 2 :
100 µg
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.