product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
CD74 Antibody
catalog :
SMC-116
quantity :
25 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
PIN.1
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, FACS
more info or order :
StressMarq Biosciences product webpage
citations: 3
Published Application/Species/Sample/DilutionReference
  • western blot; human
Schneppenheim J, Hüttl S, Kruchen A, Fluhrer R, Müller I, Saftig P, et al. Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cells. Biochem Biophys Res Commun. 2014;451:48-53 pubmed publisher
  • western blot; human; 1:1000
Katsel P, Tan W, Haroutunian V. Gain in brain immunity in the oldest-old differentiates cognitively normal from demented individuals. PLoS ONE. 2009;4:e7642 pubmed publisher
Dheilly E, Battistello E, Katanayeva N, Sungalee S, Michaux J, Duns G, et al. Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma. Cancer Cell. 2020;37:674-689.e12 pubmed publisher
image
image 1 :
StressMarq Biosciences SMC-116 image 1
Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-CD74 Monoclonal Antibody, Clone PIN 1.1 (SMC-116). Tissue: Cervical cancer cell line (HeLa). Species: Human. Fixation: 2% Formaldehyde for 20 min at RT. Primary Antibody: Mouse Anti-CD74 Monoclonal Antibody (SMC-116) at 1:100 for 12 hours at 4°C. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:200 for 2 hours at RT. Counterstain: DAPI (blue) nuclear stain at 1:40000 for 2 hours at RT. Localization: Cell membrane. Endoplasmic reticulum membrane. Golgi apparatus. Endosome. Lysosome. Magnification: 100x. (A) DAPI (blue) nuclear stain. (B) Anti-CD74 Antibody. (C) Composite.
product information
Catalog No :
SMC-116
Product Name :
CD74 Antibody
Description :
Mouse Anti-Human CD74 Monoclonal IgG1
Target :
CD74
Research Area(s) :
Immunology Adaptive Immunity B Cells B Cell CD Markers
Alternative Name(s) :
DHLAG Antibody, HLA DR gamma Antibody, HLADG Antibody, p33 Antibody, p35 Antibody, Protein 41 Antibody, CD 74 antibody, CD74 antibody, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) antibody, CD74 antigen antibody, CD74 molecule antibody, CD74 molecule, major histocompatibility complex, class II invariant chain antibody, CLIP antibody, DHLAG antibody, Gamma chain of class II antigens antibody, HG2A_HUMAN antibody, HLA class II histocompatibility antigen gamma chain antibody, HLA DR antigens associated invariant chain antibody, HLA DR gamma antibody, HLA-DR antigens-associated invariant chain antibody, HLA-DR-gamma antibody, HLADG antibody, HLADR antigens associated invariant chain antibody Ia antigen associated invariant chain antibody, Ia antigen-associated invariant chain antibody, Ia associated invariant chain antibody, Ia gamma antibody, Ii antibody, Invariant polypeptide of major histocompatibility complex class II antigen associated antibody, la-gamma antibody, Major histocompatibility complex class II invariant chain antibody, MHC HLA DR gamma chain antibody, MHC HLA-DR gamma chain antibody, p33 antibody, p35 antibody, Protein 41 antibody
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
PIN.1
Immunogen :
Human CD74 invariant chain synthetic peptide
Accession Number :
NP_001020329.1
Swiss-Prot :
P04233
Applications :
WB IHC ICC/IF IP FCM FACS
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Medium :
Human Mouse
Antibody Dilution :
WB (1:1000), IHC (1:100), ICC/IF (1:50); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Specificity :
Detects ~33-35kDa protein doublet corresponding to the molecular mass of the p33 and p35 forms of human CD74.
Cellular Localization :
Cell Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Endosome Lysosome
Size 1 :
25 µg
Size 2 :
100 µg
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.