product summary
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company name :
StressMarq Biosciences
product type :
antibody
product name :
HSP60 Antibody
catalog :
SMC-110
quantity :
50 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
LK1
reactivity :
human, mouse, rat, dogs, chicken, bovine, soybeans
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, flow cytometry
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 6g
Richter F, Dennerlein S, Nikolov M, Jans D, Naumenko N, Aich A, et al. ROMO1 is a constituent of the human presequence translocase required for YME1L protease import. J Cell Biol. 2019;218:598-614 pubmed publisher
  • western blot; mouse
Doğan S, Pujol C, Maiti P, Kukat A, Wang S, Hermans S, et al. Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart. Cell Metab. 2014;19:458-69 pubmed publisher
  • western blot; soybeans
Ahsan N, Donnart T, Nouri M, Komatsu S. Tissue-specific defense and thermo-adaptive mechanisms of soybean seedlings under heat stress revealed by proteomic approach. J Proteome Res. 2010;9:4189-204 pubmed publisher
  • western blot; soybeans
Ahsan N, Komatsu S. Comparative analyses of the proteomes of leaves and flowers at various stages of development reveal organ-specific functional differentiation of proteins in soybean. Proteomics. 2009;9:4889-907 pubmed publisher
Yamada H, Nishida K, Iwasaki Y, Isota Y, Negishi L, Siomi M. Siwi cooperates with Par-1 kinase to resolve the autoinhibitory effect of Papi for Siwi-piRISC biogenesis. Nat Commun. 2022;13:1518 pubmed publisher
Yamashiro H, Negishi M, Kinoshita T, Ishizu H, Ohtani H, Siomi M. Armitage determines Piwi-piRISC processing from precursor formation and quality control to inter-organelle translocation. EMBO Rep. 2020;21:e48769 pubmed publisher
Dumas P, Naudin C, Martin Lannerée S, Izac B, Casetti L, Mansier O, et al. Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5- and hypoxia- dependent up-regulation of AXL. Haematologica. 2019;: pubmed publisher
Nishida K, Sakakibara K, Iwasaki Y, Yamada H, Murakami R, Murota Y, et al. Hierarchical roles of mitochondrial Papi and Zucchini in Bombyx germline piRNA biogenesis. Nature. 2018;555:260-264 pubmed publisher
Saita S, Tatsuta T, Lampe P, König T, Ohba Y, Langer T. PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. EMBO J. 2018;37: pubmed publisher
Nonaka K, Une S, Komatsu M, Yamaji R, Akiyama J. Heat stress prevents the decrease in succinate dehydrogenase activity in the extensor digitorum longus of streptozotocin-induced diabetic rats. Physiol Res. 2018;67:117-126 pubmed
Vukotic M, Nolte H, König T, Saita S, Ananjew M, Kruger M, et al. Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria. Mol Cell. 2017;67:471-483.e7 pubmed publisher
Saita S, Nolte H, Fiedler K, Kashkar H, Venne A, Zahedi R, et al. PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis. Nat Cell Biol. 2017;19:318-328 pubmed publisher
Seiferling D, Szczepanowska K, Becker C, Senft K, Hermans S, Maiti P, et al. Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt. EMBO Rep. 2016;17:953-64 pubmed publisher
image
image 1 :
StressMarq Biosciences SMC-110 image 1
Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-Hsp60 Monoclonal Antibody, Clone LK-1 (SMC-110). Tissue: HaCaT cells. Species: Human. Fixation: Cold 100% methanol at -20°C for 10 minutes. Primary Antibody: Mouse Anti-Hsp60 Monoclonal Antibody (SMC-110) at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Cytoplasmic Staining.
product information
Catalog No :
SMC-110
Product Name :
HSP60 Antibody
Description :
Mouse Anti-Human HSP60 Monoclonal IgG1
Target :
HSP60
Research Area(s) :
Cancer Heat Shock Cell Signaling Protein Trafficking Chaperone Proteins Tags and Cell Markers Organelle Markers
Alternative Name(s) :
CPN60 Antibody, GROEL Antibody, HLD4 Antibody, HSP 60 Antibody, HSP65 Antibody, HSPD1 Antibody, HuCHA60 Antibody, SPG 13 Antibody
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
LK1
Immunogen :
Recombinant human HSP60
Accession Number :
NP_002147.2
Swiss-Prot :
P10809
Applications :
WB IHC IP ELISA FCM
Host Species :
Mouse
Isotype :
IgG1
Species Reactivity Medium :
Human Mouse Rat Bovine Dog Chicken Drosophila Guinea Pig Hamster Monkey Pig Rabbit Sheep Xenopus Plant Silkworm
Antibody Dilution :
WB (1:20000), IHC (1:100), ICC/IF (1:100), IP (1:200); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Specificity :
Detects ~60kDa.
Cellular Localization :
Mitochondrion Mitochondrion Matrix
Size 1 :
50 µg
Size 2 :
200 µg
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.