product summary
Loading...
company name :
StressMarq Biosciences
product type :
antibody
product name :
HSP90 alpha Antibody
catalog :
SMC-108
quantity :
25 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Hyb-K41009
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; human
Xi C, Hu Y, Buckhaults P, Moskophidis D, Mivechi N. Heat shock factor Hsf1 cooperates with ErbB2 (Her2/Neu) protein to promote mammary tumorigenesis and metastasis. J Biol Chem. 2012;287:35646-57 pubmed publisher
  • immunoprecipitation; human; 1:50
Shipp C, Watson K, Jones G. Associations of HSP90 client proteins in human breast cancer. Anticancer Res. 2011;31:2095-101 pubmed
Sakata M, Katoh H, Otsuki N, Okamoto K, Nakatsu Y, Lim C, et al. Heat Shock Protein 90 Ensures the Integrity of Rubella Virus p150 Protein and Supports Viral Replication. J Virol. 2019;93: pubmed publisher
Koyama S, Narita E, Suzuki Y, Shiina T, Taki M, Shinohara N, et al. Long-term exposure to a 40-GHz electromagnetic field does not affect genotoxicity or heat shock protein expression in HCE-T or SRA01/04 cells. J Radiat Res. 2019;60:417-423 pubmed publisher
Katoh H, Sekizuka T, Nakatsu Y, Nakagawa R, Nao N, Sakata M, et al. The R2TP complex regulates paramyxovirus RNA synthesis. PLoS Pathog. 2019;15:e1007749 pubmed publisher
Katoh H, Kubota T, Nakatsu Y, Tahara M, Kidokoro M, Takeda M. Heat Shock Protein 90 Ensures Efficient Mumps Virus Replication by Assisting with Viral Polymerase Complex Formation. J Virol. 2017;91: pubmed publisher
Koyama S, Narita E, Shimizu Y, Shiina T, Taki M, Shinohara N, et al. Twenty Four-Hour Exposure to a 0.12 THz Electromagnetic Field Does Not Affect the Genotoxicity, Morphological Changes, or Expression of Heat Shock Protein in HCE-T Cells. Int J Environ Res Public Health. 2016;13: pubmed publisher
Koyama S, Narita E, Shimizu Y, Suzuki Y, Shiina T, Taki M, et al. Effects of Long-Term Exposure to 60 GHz Millimeter-Wavelength Radiation on the Genotoxicity and Heat Shock Protein (Hsp) Expression of Cells Derived from Human Eye. Int J Environ Res Public Health. 2016;13: pubmed publisher
Ishikawa Y, Sakurai H. Heat-induced expression of the immediate-early gene IER5 and its involvement in the proliferation of heat-shocked cells. FEBS J. 2015;282:332-40 pubmed publisher
Quanz M, Herbette A, Sayarath M, de Koning L, Dubois T, Sun J, et al. Heat shock protein 90? (Hsp90?) is phosphorylated in response to DNA damage and accumulates in repair foci. J Biol Chem. 2012;287:8803-15 pubmed publisher
image
image 1 :
StressMarq Biosciences SMC-108 image 1
Immunohistochemistry analysis using Mouse Anti-Hsp90 alpha Monoclonal Antibody, Clone K41009 (SMC-108). Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 alpha Monoclonal Antibody (SMC-108) at 1:5000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. This image was produced using an amplifying IHC wash buffer. The antibody has therefore been diluted more than is recommended for other applications.
product information
Catalog No :
SMC-108
Product Name :
HSP90 alpha Antibody
Description :
Mouse Anti-Human HSP90 alpha Monoclonal IgG2a
Target :
HSP90 alpha
Research Area(s) :
Cancer Heat Shock Cell Signaling Protein Trafficking Chaperone Proteins Cancer Tumor Biomarkers
Alternative Name(s) :
HSP86 Antibody, HSP89A Antibody, HSP90A Antibody, HSP90AA1 Antibody, HSP90Alpha Antibody, HSPC1 Antibody, HSPCA Antibody, HSPCAL3 Antibody
Category :
Antibodies
Product Type :
Monoclonal
Clone Number :
Hyb-K41009
Immunogen :
Recombinant human HSP90alpha; Specificity mapped to amino acids 604-731
Accession Number :
NP_001017963.2
Swiss-Prot :
P07900
Applications :
WB IHC ELISA
Host Species :
Mouse
Isotype :
IgG2a
Species Reactivity Medium :
Human Mouse Rat
Antibody Dilution :
WB (1:1000), IHC (1:5000); optimal dilutions for assays should be determined by the user.
Purification :
Protein G Purified
Specificity :
Detects 90kDa. This is an alpha-specific product.
Cellular Localization :
Cytoplasm Melanosome
Size 1 :
25 µg
Size 2 :
100 µg
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.