HSP70/HSC70 Antibody | StressMarq Biosciences SMC-104 product information

product summary

company name :

StressMarq Biosciences

product type :

antibody

product name :

HSP70/HSC70 Antibody

catalog :

SMC-104

quantity :

200 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

N27F3-4

reactivity :

hamsters, human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

StressMarq Biosciences product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; rat	Morshed S, Ma R, Latif R, Davies T. How one TSH receptor antibody induces thyrocyte proliferation while another induces apoptosis. J Autoimmun. 2013;47:17-24 pubmed publisher
western blot; human; 1:1500	Modrow J, Preusse Prange A, Meyer P, Harder M, Schwark T, von Wurmb Schwark N. Highly reliable quantification of proteins such as members of the HSP70 superfamily based on the grey scale index via immune detection stained bands on a Western blot. Forensic Sci Int. 2012;222:256-8 pubmed publisher
western blot; human	Sun L, Prince T, Manjarrez J, Scroggins B, Matts R. Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins. Biochim Biophys Acta. 2012;1823:1092-101 pubmed publisher
immunocytochemistry; hamsters; 1:500	Mutsvunguma L, Moetlhoa B, Edkins A, Luke G, Blatch G, Knox C. Theiler's murine encephalomyelitis virus infection induces a redistribution of heat shock proteins 70 and 90 in BHK-21 cells, and is inhibited by novobiocin and geldanamycin. Cell Stress Chaperones. 2011;16:505-15 pubmed publisher
	Carrettiero D, Almeida M, Longhini A, Rauch J, Han D, Zhang X, et al. Stress routes clients to the proteasome via a BAG2 ubiquitin-independent degradation condensate. Nat Commun. 2022;13:3074 pubmed publisher
	Mediani L, Antoniani F, Galli V, Vinet J, Carrá A, Bigi I, et al. Hsp90-mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling. EMBO Rep. 2021;22:e51740 pubmed publisher
	Pillarsetty N, Jhaveri K, Taldone T, Caldas Lopes E, Punzalan B, Joshi S, et al. Paradigms for Precision Medicine in Epichaperome Cancer Therapy. Cancer Cell. 2019;36:559-573.e7 pubmed publisher
	Kim Chiaw P, Hantouche C, Wong M, Matthes E, Robert R, Hanrahan J, et al. Hsp70 and DNAJA2 limit CFTR levels through degradation. PLoS ONE. 2019;14:e0220984 pubmed publisher
	Wang S, Kojima K, Mobley J, West A. Proteomic analysis of urinary extracellular vesicles reveal biomarkers for neurologic disease. EBioMedicine. 2019;: pubmed publisher
	Reeh H, Rudolph N, Billing U, Christen H, Streif S, Bullinger E, et al. Response to IL-6 trans- and IL-6 classic signalling is determined by the ratio of the IL-6 receptor α to gp130 expression: fusing experimental insights and dynamic modelling. Cell Commun Signal. 2019;17:46 pubmed publisher
	Meister Broekema M, Freilich R, Jagadeesan C, Rauch J, Bengoechea R, Motley W, et al. Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks. Nat Commun. 2018;9:5342 pubmed publisher
	Karras G, Yi S, Sahni N, Fischer M, Xie J, Vidal M, et al. HSP90 Shapes the Consequences of Human Genetic Variation. Cell. 2017;168:856-866.e12 pubmed publisher
	Preusse Prange A, Modrow J, Schwark T, von Wurmb Schwark N. Detection of constitutive and inducible HSP70 proteins in formalin fixed human brain tissue. Forensic Sci Int. 2014;235:62-7 pubmed publisher
	Chen Q, Prior M, Dargusch R, Roberts A, Riek R, Eichmann C, et al. A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease. PLoS ONE. 2011;6:e27865 pubmed publisher
	Olkku A, Leskinen J, Lammi M, Hynynen K, Mahonen A. Ultrasound-induced activation of Wnt signaling in human MG-63 osteoblastic cells. Bone. 2010;47:320-30 pubmed publisher

image

image 1 :

Immunohistochemistry analysis using Mouse Anti-Hsp70 Monoclonal Antibody, Clone N27F3-4 (SMC-104). Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Hsp70 Monoclonal Antibody (SMC-104) at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Epidermis.

product information

Parent Catalog No. :

SMC-104

Catalog No :

SMC-104

Product Name :

HSP70/HSC70 Antibody

Description :

Mouse Anti-Human HSP70/HSC70 Monoclonal IgG1

Target :

HSP70/HSC70

Conjugate :

Unconjugated

Size 1 :

200 µg

Size 2 :

50 µg

Research Area(s) :

Cell Signaling Protein Trafficking Chaperone Proteins Cancer Tumor Biomarkers Cancer Heat Shock

Alternative Name(s) :

HSP70 1 Antibody, HSP70 2 Antibody, HSP70.1 Antibody, HSP72 Antibody, HSPA1 Antibody, HSPA1A Antibody, HSPA1B Antibody

Product Type :

Monoclonal

Clone Number :

N27F3-4

Immunogen :

Human Recombinant HSP70/HSC70

Immunogen Species :

Human

Accession Number :

NP_005336.3

Swiss-Prot :

P0DMV8/P0DMV9

Applications :

WB IHC ICC/IF IP FCM IEM

Host Species :

Mouse

Isotype :

IgG1

Species Reactivity Medium :

Human Mouse Rat Bovine C. elegans Beluga Dog Chicken Drosophila Fish Guinea Pig Hamster Monkey Pig Plant Rabbit Sheep Xenopus

Purification :

Protein G Purified

Concentration :

1 mg/ml

Specificity :

Detects ~72 (HSP) and ~73kDa (HSC).

Cellular Localization :

Cytoplasm

Image Filenames :

SMC-104_Hsp70_Antibody_N27_WB_Human_Cell-lysates_1.png
SMC-104_Hsp70_Antibody_N27_IHC_Mouse_ba
ckskin_1.png

more info or order :

StressMarq Biosciences product webpage