| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; 1:3000; fig 2
- western blot; human; 1:3000; fig 1
| Chittoor Vinod V, Lee S, Judge S, Notterpek L. Inducible HSP70 is critical in preventing the aggregation and enhancing the processing of PMP22. ASN Neuro. 2015;7: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 6h, 2g, 6s1e
| Azkanaz M, Rodríguez López A, de Boer B, Huiting W, Angrand P, Vellenga E, et al. Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock. elife. 2019;8: pubmed publisher |
| Seguin S, Morelli F, Vinet J, Amore D, De Biasi S, Poletti A, et al. Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly. Cell Death Differ. 2014;21:1838-51 pubmed publisher |
- western blot; mouse; 1:1000
| Eroglu B, Kimbler D, Pang J, Choi J, Moskophidis D, Yanasak N, et al. Therapeutic inducers of the HSP70/HSP110 protect mice against traumatic brain injury. J Neurochem. 2014;130:626-41 pubmed publisher |
| Akkad H, Corpeno R, Larsson L. Masseter muscle myofibrillar protein synthesis and degradation in an experimental critical illness myopathy model. PLoS ONE. 2014;9:e92622 pubmed publisher |
- western blot; mouse; 1:3000
| Wijeratne E, Xu Y, Scherz Shouval R, Marron M, Rocha D, Liu M, et al. Structure-activity relationships for withanolides as inducers of the cellular heat-shock response. J Med Chem. 2014;57:2851-63 pubmed publisher |
| Sheppard P, Sun X, Khammash M, Giffard R. Overexpression of heat shock protein 72 attenuates NF-?B activation using a combination of regulatory mechanisms in microglia. PLoS Comput Biol. 2014;10:e1003471 pubmed publisher |
- western blot; human; 1:1000; fig 6
| Bauckman K, Haller E, Flores I, Nanjundan M. Iron modulates cell survival in a Ras- and MAPK-dependent manner in ovarian cells. Cell Death Dis. 2013;4:e592 pubmed publisher |
- western blot; Sus
- western blot; pigs
| Aare S, Radell P, Eriksson L, Akkad H, Chen Y, Hoffman E, et al. Effects of corticosteroids in the development of limb muscle weakness in a porcine intensive care unit model. Physiol Genomics. 2013;45:312-20 pubmed publisher |
| Larkins N, Murphy R, Lamb G. Influences of temperature, oxidative stress, and phosphorylation on binding of heat shock proteins in skeletal muscle fibers. Am J Physiol Cell Physiol. 2012;303:C654-65 pubmed publisher |
- western blot; human; 1:1000
| Abisambra J, Jinwal U, Suntharalingam A, Arulselvam K, Brady S, Cockman M, et al. DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau. J Mol Biol. 2012;421:653-61 pubmed publisher |
- western blot; human; 1:3000
| Santagata S, Xu Y, Wijeratne E, Kontnik R, Rooney C, Perley C, et al. Using the heat-shock response to discover anticancer compounds that target protein homeostasis. ACS Chem Biol. 2012;7:340-9 pubmed publisher |
- western blot; human; 1:5000
| Patterson K, Ward S, Combs B, Voss K, Kanaan N, Morfini G, et al. Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport. Biochemistry. 2011;50:10300-10 pubmed publisher |
- western blot; pigs
- western blot; Sus
| Aare S, Ochala J, Norman H, Radell P, Eriksson L, Göransson H, et al. Mechanisms underlying the sparing of masticatory versus limb muscle function in an experimental critical illness model. Physiol Genomics. 2011;43:1334-50 pubmed publisher |
| Larkins N, Murphy R, Lamb G. Absolute amounts and diffusibility of HSP72, HSP25, and ?B-crystallin in fast- and slow-twitch skeletal muscle fibers of rat. Am J Physiol Cell Physiol. 2012;302:C228-39 pubmed publisher |
- immunoprecipitation; human; 1:50
| Shipp C, Watson K, Jones G. Associations of HSP90 client proteins in human breast cancer. Anticancer Res. 2011;31:2095-101 pubmed |
- immunohistochemistry; human; 1:50
- western blot; human; 1:10,000
| Wood J, Pring M, Eveson J, Price N, Proby C, Hague A. Co-overexpression of Bag-1 and heat shock protein 70 in human epidermal squamous cell carcinoma: Bag-1-mediated resistance to 5-fluorouracil-induced apoptosis. Br J Cancer. 2011;104:1459-71 pubmed publisher |
| Ochala J, Gustafson A, Diez M, Renaud G, Li M, Aare S, et al. Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: underlying mechanisms. J Physiol. 2011;589:2007-26 pubmed publisher |
- western blot; human
- western blot; mouse
| Batista Nascimento L, Neef D, Liu P, Rodrigues Pousada C, Thiele D. Deciphering human heat shock transcription factor 1 regulation via post-translational modification in yeast. PLoS ONE. 2011;6:e15976 pubmed publisher |
- western blot; human; 1:10,000
| Mitsuhashi M, Yamaguchi M, Kojima T, Nakajima R, Kasai K. Effects of HSP70 on the compression force-induced TNF-? and RANKL expression in human periodontal ligament cells. Inflamm Res. 2011;60:187-94 pubmed publisher |
| Fernández Llama P, Khositseth S, Gonzales P, Star R, Pisitkun T, Knepper M. Tamm-Horsfall protein and urinary exosome isolation. Kidney Int. 2010;77:736-42 pubmed publisher |
- western blot; pigs
- western blot; Sus
| Banduseela V, Ochala J, Chen Y, Göransson H, Norman H, Radell P, et al. Gene expression and muscle fiber function in a porcine ICU model. Physiol Genomics. 2009;39:141-59 pubmed publisher |
| Zwang N, Hoffert J, Pisitkun T, Moeller H, Fenton R, Knepper M. Identification of phosphorylation-dependent binding partners of aquaporin-2 using protein mass spectrometry. J Proteome Res. 2009;8:1540-54 pubmed publisher |
| Xu Y, Marron M, Seddon E, McLaughlin S, Ray D, Whitesell L, et al. 2,3-Dihydrowithaferin A-3beta-O-sulfate, a new potential prodrug of withaferin A from aeroponically grown Withania somnifera. Bioorg Med Chem. 2009;17:2210-4 pubmed publisher |
| Okusha Y, Guerrero Gimenez M, Lang B, Borges T, Stevenson M, Truman A, et al. MicroRNA-570 targets the HSP chaperone network, increases proteotoxic stress and inhibits mammary tumor cell migration. Sci Rep. 2022;12:15582 pubmed publisher |
| Gao C, Gu J, Zhang H, Jiang K, Tang L, Liu R, et al. Hyperosmotic-stress-induced liquid-liquid phase separation of ALS-related proteins in the nucleus. Cell Rep. 2022;40:111086 pubmed publisher |
| Zhang Y, VanHecke G, Ahn Y, Proby C, Dinkova Kostova A. Sulfoxythiocarbamate S-4 inhibits HSP90 in human cutaneous squamous cell carcinoma cells. Eur J Pharmacol. 2020;889:173609 pubmed publisher |
| Fang C, Kuo H, Hsu S, Yih L. HSP70 regulates Eg5 distribution within the mitotic spindle and modulates the cytotoxicity of Eg5 inhibitors. Cell Death Dis. 2020;11:715 pubmed publisher |
| Kuta R, Larochelle N, Fernandez M, Pal A, Minotti S, Tibshirani M, et al. Depending on the stress, histone deacetylase inhibitors act as heat shock protein co-inducers in motor neurons and potentiate arimoclomol, exerting neuroprotection through multiple mechanisms in ALS models. Cell Stress Chaperones. 2020;25:173-191 pubmed publisher |
| von Horn C, Minor T. Transient hyperthermia during oxygenated rewarming of isolated rat livers. Transpl Int. 2020;33:272-278 pubmed publisher |
| Koyama S, Narita E, Suzuki Y, Shiina T, Taki M, Shinohara N, et al. Long-term exposure to a 40-GHz electromagnetic field does not affect genotoxicity or heat shock protein expression in HCE-T or SRA01/04 cells. J Radiat Res. 2019;60:417-423 pubmed publisher |
| Portillo J, Van Grol J, Saffo S, Lopez Corcino Y, Rodríguez M, Fox B, et al. CD40 in endothelial cells restricts neural tissue invasion by Toxoplasma gondii. Infect Immun. 2019;: pubmed publisher |
| Wadhwa R, Li L, Singh R, Wang J, Gao R, Nigam N, et al. Modulation of Diacylglycerol-Induced Melanogenesis in Human Melanoma and Primary Melanocytes: Role of Stress Chaperone Mortalin. Evid Based Complement Alternat Med. 2019;2019:9848969 pubmed publisher |
| Arnold F, Pluciennik A, Merry D. Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy. Sci Rep. 2019;9:119 pubmed publisher |
| Ueda T, Kohama Y, Sakurai H. IER family proteins are regulators of protein phosphatase PP2A and modulate the phosphorylation status of CDC25A. Cell Signal. 2019;55:81-89 pubmed publisher |
| Kitano S, Kondo T, Matsuyama R, Ono K, Goto R, Takaki Y, et al. Impact of hepatic HSP72 on insulin signaling. Am J Physiol Endocrinol Metab. 2019;316:E305-E318 pubmed publisher |
| Tian Z, Dong C, Fujita A, Fujita Y, Hashimoto K. Expression of heat shock protein HSP-70 in the retrosplenial cortex of rat brain after administration of (R,S)-ketamine and (S)-ketamine, but not (R)-ketamine. Pharmacol Biochem Behav. 2018;172:17-21 pubmed publisher |
| Jin X, Qiao A, Moskophidis D, Mivechi N. Modulation of Heat Shock Factor 1 Activity through Silencing of Ser303/Ser307 Phosphorylation Supports a Metabolic Program Leading to Age-Related Obesity and Insulin Resistance. Mol Cell Biol. 2018;38: pubmed publisher |
| Girard P, Peynot N, Lelièvre J. Differential correlations between changes to glutathione redox state, protein ubiquitination, and stress-inducible HSPA chaperone expression after different types of oxidative stress. Cell Stress Chaperones. 2018;23:985-1002 pubmed publisher |
| Yukawa H, Suzuki K, Aoki K, Arimoto T, Yasui T, Kaji N, et al. Imaging of angiogenesis of human umbilical vein endothelial cells by uptake of exosomes secreted from hepatocellular carcinoma cells. Sci Rep. 2018;8:6765 pubmed publisher |
| Muralidharan S, Lim A, Catalano D, Mandrekar P. Human Binge Alcohol Intake Inhibits TLR4-MyD88 and TLR4-TRIF Responses but Not the TLR3-TRIF Pathway: HspA1A and PP1 Play Selective Regulatory Roles. J Immunol. 2018;200:2291-2303 pubmed publisher |
| Bhattacharya K, Bernasconi L, Picard D. Luminescence resonance energy transfer between genetically encoded donor and acceptor for protein-protein interaction studies in the molecular chaperone HSP70/HSP90 complexes. Sci Rep. 2018;8:2801 pubmed publisher |
| Stangl S, Foulds G, Fellinger H, Pilkington G, Pockley A, Multhoff G. Immunohistochemical and Flow Cytometric Analysis of Intracellular and Membrane-Bound Hsp70, as a Putative Biomarker of Glioblastoma Multiforme, Using the cmHsp70.1 Monoclonal Antibody. Methods Mol Biol. 2018;1709:307-320 pubmed publisher |
| Jin X, Qiao A, Moskophidis D, Mivechi N. WITHDRAWN: Abrogation of heat shock factor 1 (Hsf1) phosphorylation deregulates its activity and lowers activation threshold, leading to obesity in mice. J Biol Chem. 2017;: pubmed publisher |
| Qiao A, Jin X, Pang J, Moskophidis D, Mivechi N. The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis. J Cell Biol. 2017;216:723-741 pubmed publisher |
| Katoh H, Kubota T, Nakatsu Y, Tahara M, Kidokoro M, Takeda M. Heat Shock Protein 90 Ensures Efficient Mumps Virus Replication by Assisting with Viral Polymerase Complex Formation. J Virol. 2017;91: pubmed publisher |
| Kawaguchi Y, Taoka M, Takekiyo T, Uekita T, Shoji I, Hachiya N, et al. TRIM32-Cytoplasmic-Body Formation Is an ATP-Consuming Process Stimulated by HSP70 in Cells. PLoS ONE. 2017;12:e0169436 pubmed publisher |
| Ogilvie H, Cacciani N, Akkad H, Larsson L. Targeting Heat Shock Proteins Mitigates Ventilator Induced Diaphragm Muscle Dysfunction in an Age-Dependent Manner. Front Physiol. 2016;7:417 pubmed |
| Koyama S, Narita E, Shimizu Y, Shiina T, Taki M, Shinohara N, et al. Twenty Four-Hour Exposure to a 0.12 THz Electromagnetic Field Does Not Affect the Genotoxicity, Morphological Changes, or Expression of Heat Shock Protein in HCE-T Cells. Int J Environ Res Public Health. 2016;13: pubmed publisher |
| Hu Y, Wang Y, Liang S, Yu X, Zhang L, Feng L, et al. Senkyunolide I attenuates oxygen-glucose deprivation/reoxygenation-induced inflammation in microglial cells. Brain Res. 2016;1649:123-131 pubmed publisher |
| Koyama S, Narita E, Shimizu Y, Suzuki Y, Shiina T, Taki M, et al. Effects of Long-Term Exposure to 60 GHz Millimeter-Wavelength Radiation on the Genotoxicity and Heat Shock Protein (Hsp) Expression of Cells Derived from Human Eye. Int J Environ Res Public Health. 2016;13: pubmed publisher |
| Kunihiro M, Fujii H, Miyagi T, Takahashi Y, Tanaka R, Fukushima T, et al. Heat Shock Enhances the Expression of the Human T Cell Leukemia Virus Type-I (HTLV-I) Trans-Activator (Tax) Antigen in Human HTLV-I Infected Primary and Cultured T Cells. Viruses. 2016;8: pubmed publisher |
| Dayalan Naidu S, Sutherland C, Zhang Y, Risco A, de La Vega L, Caunt C, et al. Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases. Mol Cell Biol. 2016;36:2403-17 pubmed publisher |
| Katoh H, Kubota T, Kita S, Nakatsu Y, Aoki N, Mori Y, et al. Heat shock protein 70 regulates degradation of the mumps virus phosphoprotein via the ubiquitin-proteasome pathway. J Virol. 2015;89:3188-99 pubmed publisher |
| Richter C, Viergutz T, Schwerin M, Weitzel J. Prostaglandin E synthase interacts with inducible heat shock protein 70 after heat stress in bovine primary dermal fibroblast cells. Cytometry A. 2015;87:61-7 pubmed publisher |
| Engels M, Bilgic E, Pinto A, Vásquez E, Wollschläger L, Steinbrenner H, et al. A cardiopulmonary bypass with deep hypothermic circulatory arrest rat model for the investigation of the systemic inflammation response and induced organ damage. J Inflamm (Lond). 2014;11:26 pubmed publisher |
| Dang V, Tanabe K, Tanaka Y, Tokumoto N, Misumi T, Saeki Y, et al. Fasting enhances TRAIL-mediated liver natural killer cell activity via HSP70 upregulation. PLoS ONE. 2014;9:e110748 pubmed publisher |
| Ishikawa Y, Sakurai H. Heat-induced expression of the immediate-early gene IER5 and its involvement in the proliferation of heat-shocked cells. FEBS J. 2015;282:332-40 pubmed publisher |
| Berger A, Ivanova E, Gareau C, Scherrer A, Mazroui R, Strub K. Direct binding of the Alu binding protein dimer SRP9/14 to 40S ribosomal subunits promotes stress granule formation and is regulated by Alu RNA. Nucleic Acids Res. 2014;42:11203-17 pubmed publisher |
| Kanegasaki S, Matsushima K, Shiraishi K, Nakagawa K, Tsuchiya T. Macrophage inflammatory protein derivative ECI301 enhances the alarmin-associated abscopal benefits of tumor radiotherapy. Cancer Res. 2014;74:5070-8 pubmed publisher |
| Muralidharan S, Ambade A, Fulham M, Deshpande J, Catalano D, Mandrekar P. Moderate alcohol induces stress proteins HSF1 and hsp70 and inhibits proinflammatory cytokines resulting in endotoxin tolerance. J Immunol. 2014;193:1975-87 pubmed publisher |
| Preusse Prange A, Modrow J, Schwark T, von Wurmb Schwark N. Detection of constitutive and inducible HSP70 proteins in formalin fixed human brain tissue. Forensic Sci Int. 2014;235:62-7 pubmed publisher |
| Chanoux R, Robay A, Shubin C, Kebler C, Suaud L, Rubenstein R. Hsp70 promotes epithelial sodium channel functional expression by increasing its association with coat complex II and its exit from endoplasmic reticulum. J Biol Chem. 2012;287:19255-65 pubmed publisher |
