This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
StressMarq Biosciences
product type :
chemical
product name :
Teprenone
catalog :
SIH-526-10MG
product information
Catalog No :
SIH-526-10MG
Product Name :
Teprenone
Description :
HSP70 Inducer
Research Area(s) :
Cancer Heat Shock Cell Signaling Neuroscience
Alternative Name(s) :
Geranylgeranylacetone, GGA, 6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one
Product Type :
Inducer
CAS No :
6809-52-5
MolecularFormula :
C23H38O
Molecular Weight :
330.6
Source :
Synthetic
Purity :
>95% (GC)
PubChem CID :
5282199
Scientific Background :
Teprenone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects) (1, 2). Reports indicate that Teprenone protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression (2). Other studies have shown that it induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice (3, 4).
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.