product summary
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company name :
StressMarq Biosciences
product type :
chemical
product name :
Sorafenib
catalog :
SIH-476
quantity :
10 mg
more info or order :
StressMarq Biosciences product webpage
citations: 1
Reference
Okumura D, Hagino M, Yamagishi A, Kaibori Y, Munira S, Saito Y, et al. Inhibitors of the VEGF Receptor Suppress HeLa S3 Cell Proliferation via Misalignment of Chromosomes and Rotation of the Mitotic Spindle, Causing a Delay in M-Phase Progression. Int J Mol Sci. 2018;19: pubmed publisher
image
image 1 :
StressMarq Biosciences SIH-476 image 1
Chemical structure of Sorafenib (SIH-476), a Raf-1 inhibitor (and other kinases). CAS #: 2884461-73-0. Molecular Formula: C21H16ClF3N4O3. Molecular Weight: 464.8 g/mol.
product information
Catalog No :
SIH-476
Product Name :
Sorafenib
Size :
10 mg
Description :
Raf-1 kinase inhibitor
Research Area(s) :
Cell Signaling
Alternative Name(s) :
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide; 4-methylbenzenesulfonic acid
Category :
Small Molecules
Product Type :
Inhibitor
CAS No :
284461-73-0
Molecular Formula :
C21H16ClF3N4O3
Molecular Weight :
464.8
Source :
Synthetic
Purity :
>99%
SD File :
C28H24ClF3N4O6S APtclcactv07281415122D 0 0.00000 0.00000 67 69 0 0 0 0 0 0 0 0999 V2000 5.6719 11.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5380 10.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4040 12.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2700 7.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2700 6.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0021 6.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0021 7.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0021 3.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.7341 4.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8681 5.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 7.7750 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 6.1550 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8059 6.1550 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8059 7.7750 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 0.7830 4.9650 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.4030 4.3450 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.0230 4.9650 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7341 0.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8070 10.9300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6730 9.4300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2711 1.9300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5380 12.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6719 12.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4040 11.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1360 8.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1360 6.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.0021 4.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8681 3.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.4040 9.1200 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 10.0021 1.6200 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.2700 9.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.8681 2.1200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.1360 5.1200 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.5369 7.4650 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5369 6.4650 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2690 6.4650 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.2690 7.4650 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8059 12.6200 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0 1.4030 4.9650 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.2700 10.6200 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 9.1360 9.1200 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 11.7341 1.6200 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 6.5380 14.6200 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 7.5380 13.6200 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 5.5380 13.6200 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 1.4030 7.9650 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.4030 5.9650 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.5380 13.6200 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.9399 10.2750 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.4030 8.9650 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.4030 8.9650 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 1.4030 9.9650 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 11.7341 3.6200 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 1.4030 8.9650 0.0000 S 0 0 0 0 0 0 0 0 0 0 0 0 5.1350 10.8100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5380 10.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.9409 12.4300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7331 7.9300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7331 6.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5390 6.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.5390 7.9300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4651 3.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.2711 4.9300 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.8681 5.7400 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.1141 0.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.7341 0.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.3541 0.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 43 48 1 0 0 0 0 44 48 1 0 0 0 0 45 48 1 0 0 0 0 22 48 1 0 0 0 0 22 23 1 0 0 0 0 3 22 2 0 0 0 0 1 23 2 0 0 0 0 23 38 1 0 0 0 0 1 2 1 0 0 0 0 2 24 2 0 0 0 0 3 24 1 0 0 0 0 24 40 1 0 0 0 0 31 40 1 0 0 0 0 29 31 2 0 0 0 0 31 41 1 0 0 0 0 25 41 1 0 0 0 0 4 25 1 0 0 0 0 7 25 2 0 0 0 0 4 5 2 0 0 0 0 5 26 1 0 0 0 0 6 26 2 0 0 0 0 26 33 1 0 0 0 0 6 7 1 0 0 0 0 27 33 1 0 0 0 0 8 27 1 0 0 0 0 10 27 2 0 0 0 0 8 28 2 0 0 0 0 28 53 1 0 0 0 0 28 32 1 0 0 0 0 9 53 2 0 0 0 0 9 10 1 0 0 0 0 30 32 2 0 0 0 0 32 42 1 0 0 0 0 18 42 1 0 0 0 0 50 54 2 0 0 0 0 51 54 2 0 0 0 0 52 54 1 0 0 0 0 46 54 1 0 0 0 0 34 46 1 0 0 0 0 37 46 2 0 0 0 0 34 35 2 0 0 0 0 35 47 1 0 0 0 0 36 47 2 0 0 0 0 39 47 1 0 0 0 0 36 37 1 0 0 0 0 1 55 1 0 0 0 0 2 56 1 0 0 0 0 3 57 1 0 0 0 0 19 40 1 0 0 0 0 20 41 1 0 0 0 0 4 58 1 0 0 0 0 5 59 1 0 0 0 0 6 60 1 0 0 0 0 7 61 1 0 0 0 0 8 62 1 0 0 0 0 9 63 1 0 0 0 0 10 64 1 0 0 0 0 21 42 1 0 0 0 0 18 65 1 0 0 0 0 18 66 1 0 0 0 0 18 67 1 0 0 0 0 49 52 1 0 0 0 0 11 34 1 0 0 0 0 12 35 1 0 0 0 0 13 36 1 0 0 0 0 14 37 1 0 0 0 0 15 39 1 0 0 0 0 16 39 1 0 0 0 0 17 39 1 0 0 0 0 M END $$$$
PubChem CID :
216239
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.