product summary
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company name :
StressMarq Biosciences
product type :
chemical
product name :
Nilotinib
catalog :
SIH-463
quantity :
5 mg
more info or order :
StressMarq Biosciences product webpage
citations: 1
Reference
Okumura D, Hagino M, Yamagishi A, Kaibori Y, Munira S, Saito Y, et al. Inhibitors of the VEGF Receptor Suppress HeLa S3 Cell Proliferation via Misalignment of Chromosomes and Rotation of the Mitotic Spindle, Causing a Delay in M-Phase Progression. Int J Mol Sci. 2018;19: pubmed publisher
image
image 1 :
StressMarq Biosciences SIH-463 image 1
Chemical structure of Nilotinib (SIH-463), a BCR-ABL kinase inhibitor. CAS #: 641571-10-0. Molecular Formula: C28H22F3N7O. Molecular Weight: 529.5 g/mol.
product information
Catalog No :
SIH-463
Product Name :
Nilotinib
Size :
5 mg
Description :
BCR-ABL kinase inhibitor
Research Area(s) :
Cell Signaling Cancer Apoptosis Cancer Growth Inhibitors Tyrosine Kinase Inhibitors
Alternative Name(s) :
4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
Category :
Small Molecules
Product Type :
Inhibitor
CAS No :
641571-10-0
Molecular Formula :
C28H22F3N7O
Molecular Weight :
529.5
Source :
Synthetic
Purity :
≥99%
SD File :
C28H22F3N7O APtclcactv07281415082D 0 0.00000 0.00000 61 65 0 0 0 0 0 0 0 0999 V2000 3.7321 3.3261 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 3.3261 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 1.8261 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4071 5.4139 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7891 5.4139 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 -0.6739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 0.8261 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 0.3261 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 -3.6739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 -2.6739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 -5.6739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 -5.6739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 -6.6739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 -7.1739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7942 -1.1739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6859 7.1739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.8671 2.1361 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5991 -2.4839 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 3.8261 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7321 2.3261 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 2.3261 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 0.3261 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 -1.1739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 -0.6739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.0981 6.3649 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 -2.6739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 -4.1739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 -5.1739 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 0.3261 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 0.8261 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 1.8261 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 1.3261 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 3.3660 0.9600 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 2.3660 2.6921 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 4.0981 6.3649 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 -3.6739 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 -2.1739 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 1.8261 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 -2.1739 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 -6.6739 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 4.8261 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 3.1951 3.6361 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0010 3.6361 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 1.2061 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9967 5.2223 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1994 5.2223 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6592 -0.9839 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 1.4461 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4651 0.6361 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9272 -3.9839 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9272 -2.3639 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4842 -1.7109 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3312 -1.4839 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1042 -0.6370 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.1875 6.8095 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0503 7.6755 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1843 7.5384 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7331 -5.3639 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9272 -5.3639 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.9272 -6.9839 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 -7.7939 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 32 38 1 0 0 0 0 33 38 1 0 0 0 0 34 38 1 0 0 0 0 29 30 2 0 0 0 0 19 41 1 0 0 0 0 4 41 1 0 0 0 0 5 41 1 0 0 0 0 21 31 1 0 0 0 0 30 31 1 0 0 0 0 23 39 1 0 0 0 0 26 39 1 0 0 0 0 5 35 2 0 0 0 0 25 35 1 0 0 0 0 26 36 2 0 0 0 0 27 36 1 0 0 0 0 26 37 1 0 0 0 0 10 37 2 0 0 0 0 11 40 1 0 0 0 0 14 40 2 0 0 0 0 1 19 2 0 0 0 0 2 19 1 0 0 0 0 20 38 1 0 0 0 0 1 20 1 0 0 0 0 3 20 2 0 0 0 0 2 21 2 0 0 0 0 3 21 1 0 0 0 0 22 30 1 0 0 0 0 6 22 2 0 0 0 0 7 22 1 0 0 0 0 6 23 1 0 0 0 0 23 24 2 0 0 0 0 4 25 2 0 0 0 0 8 24 1 0 0 0 0 15 24 1 0 0 0 0 16 25 1 0 0 0 0 7 8 2 0 0 0 0 27 28 1 0 0 0 0 9 27 2 0 0 0 0 11 28 2 0 0 0 0 12 28 1 0 0 0 0 9 10 1 0 0 0 0 12 13 2 0 0 0 0 13 14 1 0 0 0 0 17 31 1 0 0 0 0 18 39 1 0 0 0 0 1 42 1 0 0 0 0 2 43 1 0 0 0 0 3 44 1 0 0 0 0 4 45 1 0 0 0 0 5 46 1 0 0 0 0 6 47 1 0 0 0 0 7 48 1 0 0 0 0 8 49 1 0 0 0 0 9 50 1 0 0 0 0 10 51 1 0 0 0 0 15 52 1 0 0 0 0 15 53 1 0 0 0 0 15 54 1 0 0 0 0 16 55 1 0 0 0 0 16 56 1 0 0 0 0 16 57 1 0 0 0 0 11 58 1 0 0 0 0 12 59 1 0 0 0 0 13 60 1 0 0 0 0 14 61 1 0 0 0 0 M END $$$$
PubChem CID :
644241
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.